Andrographolide and bone destruction
This study shows that andrographolide inhibits the development of osteoclasts ( = the cells that chew away at our bones, which is fine in a healthy situation, not fine in cancer where everything goes nutso), while increasing the presence of osteoblasts (bone builders). The researchers say that the current therapies used to treat osteolytic diseases have many unwanted side effects. And they’re not just referring to bisphosphonates (which can cause osteonecrosis of the jaw) but also to new treatments such as the monoclonal antibody denosumab, Denosumab can cause low calcium levels, weakness, constipation, back/arm/leg pa...
Source: Margaret's Corner - February 21, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll Source Type: blogs

Expert advice on how to quit smoking
Okay, everyone knows smoking is bad for you, the number one cause of preventable death in the US and the world, a direct cause of lung and heart disease and cancer… et cetera. So let’s get right down to the nitty-gritty: quitting smoking is tough. What can people do to quit? To answer this question, I spoke with my colleague Nancy Rigotti, MD. Dr. Rigotti is director of the Massachusetts General Hospital Tobacco Research and Treatment Center. She has extensively researched nicotine and tobacco, evaluated public policies on tobacco, contributed to US Surgeon General’s Reports, and authored clinical guidelines on smoki...
Source: Harvard Health Blog - February 8, 2018 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Health Heart Health Lung disease Prevention Smoking cessation Source Type: blogs

A drug problem in rural Georgia
Meet Johnathan, a 34-year-old male from rural Georgia we recently treated for back pain as a result of some extra contractor work he took on over the holidays.  We see patients like him every 11 minutes, which doesn’t leave much time to get beyond Johnathan’s chief complaint.  He leaves with his first prescription for opioids. *** Of the 91 Americans taken each day, Georgia now claims four, or more than twice our share.  Deaths from prescription opioid overdoses increased tenfold between 1999 and 2015, compared to fourfold nationally, putting us among the nation’s top 10 states with the most deaths from opioid ove...
Source: Kevin, M.D. - Medical Weblog - February 5, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/ashish-advani" rel="tag" > Ashish Advani, PharmD < /a > Tags: Meds Pain Management Primary Care Source Type: blogs

Be ketotic . . . but only sometime
Achieving ketosis by engaging in a very low-carbohydrate, high-fat lifestyle is an effective means of losing weight, breaking insulin and leptin resistance, reversing type 2 diabetes and fatty liver, reducing blood pressure, reversing the inflammation of visceral fat, and may even cause partial or total remission of selected cancers. So what’s the problem? The problem comes when people remain ketotic for extended periods. We know with confidence that long-term ketosis poses substantial risk for health complications because thousands of children have followed ketogenic diets over the years as a means of suppressing in...
Source: Wheat Belly Blog - February 2, 2018 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle Source Type: blogs

The Quest for Safer Opioid Drugs | The Scientist Magazine
Opioid drugs are well-established double-edged swords. Extremely effective at analgesia, they cause an array of harmful side effects throughout the body, including itching, constipation, and respiratory depression —the slowed breathing that ultimately causes death in overdose cases. What's more, the body's interaction with opioids is dynamic: our receptors for these compounds become desensitized to the drugs' activity over time, requiring ever larger doses to suppress pain and eventually provoking severe dependence and protracted withdrawal.In the past few years, these side effects have plagued growing number...
Source: Psychology of Pain - January 22, 2018 Category: Anesthesiology Source Type: blogs

Lactbacillus reuteri: Key to youthfulness?
Microbial species in the genus Lactobacillus, found in the human intestine as well as in fermented foods like yogurt and kefir, are known to provide health benefits to us. A number of important health benefits have been associated with increased populations of intestinal Lactobacillus, such as protection from fungal/Candidal overgrowth and vaginitis, reduction of the dysbiosis of irritable bowel syndrome/small intestinal bacterial overgrowth, and reduced unhealthy oral bacteria (e.g., Streptococcus mutans) that cause cavities. Of the nearly 200 known species of Lactobacillus, however, one species is beginning to stand out:...
Source: Wheat Belly Blog - January 3, 2018 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle anti-aging bowel flora Dr. Davis grain-free grains health healthcare reuteri testosterone Source Type: blogs

Lactobacillus reuteri: Key to youthfulness?
Microbial species in the genus Lactobacillus, found in the human intestine as well as in fermented foods like yogurt and kefir, are known to provide health benefits to us. A number of important health benefits have been associated with increased populations of intestinal Lactobacillus, such as protection from fungal/Candidal overgrowth and vaginitis, reduction of the dysbiosis of irritable bowel syndrome/small intestinal bacterial overgrowth, and reduced unhealthy oral bacteria (e.g., Streptococcus mutans) that cause cavities. Of the nearly 200 known species of Lactobacillus, however, one species is beginning to stand out:...
Source: Wheat Belly Blog - January 3, 2018 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle anti-aging bowel flora Dr. Davis grain-free grains health healthcare reuteri testosterone Source Type: blogs

How Do You Get an Alzheimer's Patient to Cooperate
One of the biggest problems we face as caregivers is How to get an Alzheimer's Patient to cooperate.By Bob DeMarcoAlzheimer's Reading RoomIn order to get an Alzheimer's Patient to cooperate you need to make some changes in the way you communicate. If you continue to try and explain why you want cooperation you are usually using too many words.Trying to convince a person living with dementia rarely works.Instead of convincing you need to learn how to use fewer words; and,how to guide your loved one.Here are 7 good articles that should help you accomplish this mission.7 Ways to Get an Alzheimer's Patient to CooperateSub...
Source: Alzheimer's Reading Room, The - January 2, 2018 Category: Neurology Tags: alzheimer's care home alzheimer's cooperation care of dementia patient dementia care how to get cooperation Source Type: blogs

Alzheimer's Care and the Dreaded Constipation Problem
This article is about implementing a solution to a problem - bowel movements, constipation, and Alzheimer's disease.Subscribe to the Alzheimer's Reading - This is a Free Service - Join NowI knew the solution to the dreaded bowel movement problem for years. I just couldn't get my mother tocooperate. When she wouldn't cooperate, I would give up. At least three or four times over a two year period.I was finally able to implement my solution for one simple reason --I was learning new and better techniques as an Alzheimer's caregiver over time.Learning How to Communicate with Someone Living with Alzheimer'sIn this case, I marri...
Source: Alzheimer's Reading Room, The - December 18, 2017 Category: Neurology Tags: alzheimer's bowel movement alzheimer's care bowel movement problems in elderly care of dementia patients at home dementia care dementia constipation help alzheimer's Source Type: blogs

They Call Me Doctor Poop
One of the biggest dementia care problems we face is problems with bowel movements and constipation.By Bob DeMarcoAlzheimer's Reading RoomYesterday was a crappy day. More succinctly, a poop agita day.It started with Dotty repeatedly telling me she had to poop.A few minutes after I got Dotty out of bed she kept saying, I want to get back in bed. Why? She had to poop and couldn't do it. Six times in a little over an hour up down - no poop.Coping with DementiaKeep in mind this entails:getting Dotty out of bed and into the wheelchair, out of the wheelchair and on to the toilet, off the toilet and into the wheelchair, out of th...
Source: Alzheimer's Reading Room, The - December 18, 2017 Category: Neurology Tags: Alzheimer's Communication alzheimer's constipation alzheimers bowel movement alzheimers care dementia care help alzheimer's help with dementia care how to communicate with dementia patients Source Type: blogs

To this physician, thankfulness is his lifeline
The complaint was constipation. In the exam room, a quiet girl stood in a too big johnny, her eyes staring down at the floor. The 13-year-old was here with her “aunt.” Like over 50,000 children before her, she’d made the fifteen hundred mile plus journey from El Salvador to escape the violence of government and gang fighting, perhaps not knowing Mara Salvatrucha and the other gangs hung out only a few blocks away from the health center. Her heart and lungs sounded fine, and her abdomen was soft with good bowel sounds. An inspection of her backside revealed sheets of condyloma cascading over her perineum and obstructi...
Source: Kevin, M.D. - Medical Weblog - December 17, 2017 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/jeffrey-collins" rel="tag" > Jeffrey Collins, MD < /a > Tags: Physician Emergency Medicine Pediatrics Source Type: blogs

The Most Natural Treatment for Constipation
In the middle of an otherwise complicated visit, an older woman reminded me of a very basic treatment for constipation that she discovered 40 years prior.  It involves no medication, no special diet, and no unpleasant bowel regimen.  It does, however, require a certain maturity of character.  This technique demands assertiveness, social bravery, and a […] The post The Most Natural Treatment for Constipation appeared first on The Examining Room of Dr. Charles. (Source: The Examining Room of Dr. Charles)
Source: The Examining Room of Dr. Charles - December 14, 2017 Category: Primary Care Authors: drcharles Tags: Uncategorized Source Type: blogs

Health Care Needs Its Rosa Parks Moment
BY SHANNON BROWNLEE On Wednesday, October 25, 2017 I was at the inaugural Society for Participatory Medicine conference. It was a fantastic day and the ending keynote was the superb Shannon Brownlee. It was great to catch up with her and I’m grateful that she agreed to let THCB publish her speech. Settle back with a cup of coffee (or as it’s Thanksgiving, perhaps something stronger), and enjoy–Matthew Holt George Burns once said, the secret to a good sermon is to have a good beginning and a good ending—and to have the two as close together as possible. I think the same is true of final keynotes after a...
Source: The Health Care Blog - November 22, 2017 Category: Consumer Health News Authors: Matthew Holt Tags: OP-ED Patients Physicians Lown Institute Overtreatment Right Choice Alliance Shannon Brownlee Society for Participatory Medicine Source Type: blogs