Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
The Risk of Crimean Congo Haemorrhagic Fever in India as a Growing Health Concern
This article includes all the cases of CCHF that have occurred in India from the year 2011, along with the fatality rates associated with this disease. Also this study discusses the need to explore some specific drugs for the management and prevention of such diseases. In addition, the pathogenesis of the disease progression, along with some protective measures suggested by the government has been described for prevention of CCHF. Subsequently, this article attempted to draw attention towards the risk that may be posed by CCHF in the coming scenario, emphasizing the importance of taking proactive measures in anticipation o...
Source: Infectious Disorders Drug Targets - March 19, 2024 Category: Infectious Diseases Authors: Gurisha Garg Sonakshi Garg Raj Kamal Balak Das Amandeep Singh Source Type: research
The role of the Flb protein family in the life cycle of Aspergillus niger
Antonie Van Leeuwenhoek. 2024 Mar 19;117(1):58. doi: 10.1007/s10482-024-01957-x.ABSTRACTGenes flbA-E are involved in sporulation and vegetative growth in Aspergillus nidulans. Inactivation of either of these genes results in a fluffy phenotype with delayed or even abolished sporulation. Previously, a non-sporulating phenotype was obtained by inactivating flbA in Aspergillus niger, which was accompanied by lysis, thinner cell walls, and an increased secretome complexity. Here, we further studied the role of the flb genes of A. niger. Strains ΔflbA, ΔflbB and ΔflbE showed increased biomass formation, while inactivation of...
Source: Antonie van Leeuwenhoek - March 19, 2024 Category: Microbiology Authors: Xiaoyi Chen Juan P Moran Torres Han A B W östen Source Type: research
The Risk of Crimean Congo Haemorrhagic Fever in India as a Growing Health Concern
This article includes all the cases of CCHF that have occurred in India from the year 2011, along with the fatality rates associated with this disease. Also this study discusses the need to explore some specific drugs for the management and prevention of such diseases. In addition, the pathogenesis of the disease progression, along with some protective measures suggested by the government has been described for prevention of CCHF. Subsequently, this article attempted to draw attention towards the risk that may be posed by CCHF in the coming scenario, emphasizing the importance of taking proactive measures in anticipation o...
Source: Infectious Disorders Drug Targets - March 19, 2024 Category: Infectious Diseases Authors: Gurisha Garg Sonakshi Garg Raj Kamal Balak Das Amandeep Singh Source Type: research
The role of the Flb protein family in the life cycle of Aspergillus niger
Antonie Van Leeuwenhoek. 2024 Mar 19;117(1):58. doi: 10.1007/s10482-024-01957-x.ABSTRACTGenes flbA-E are involved in sporulation and vegetative growth in Aspergillus nidulans. Inactivation of either of these genes results in a fluffy phenotype with delayed or even abolished sporulation. Previously, a non-sporulating phenotype was obtained by inactivating flbA in Aspergillus niger, which was accompanied by lysis, thinner cell walls, and an increased secretome complexity. Here, we further studied the role of the flb genes of A. niger. Strains ΔflbA, ΔflbB and ΔflbE showed increased biomass formation, while inactivation of...
Source: Antonie van Leeuwenhoek - March 19, 2024 Category: Microbiology Authors: Xiaoyi Chen Juan P Moran Torres Han A B W östen Source Type: research
