Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)
Conditions: Human African Trypanosomiasis Interventions: Drug: Treatment of seropositive individuals (positive serology test, but parasitology not confirmed) Sponsors: Drugs for Neglected Diseases; Institute of Tropical Medicine, Belgium; Institut de Recherche pour le Developpement; Institut National de Recherche Biom édicale. Kinshasa, République Démocratique du Congo; Ministry of Public Health, Democratic Republic of the Congo Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Azithromycin Reduction to Reach Elimination of Trachoma B
Conditions: Trachoma Interventions: Drug: Azithromycin Sponsors: University of California, San Francisco; Institut National de Recherche Biom édicale. Kinshasa, République Démocratique du Congo; National Eye Institute (NEI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
A 3- to 5-day Clinical Trial of Levamisole in Loiasis Infected Subjects
Conditions: Loiasis Interventions: Drug: Levamisole 3 days; Drug: Levamisole 5 days; Drug: Placebo Sponsors: Programme National de Lutte contre l ' Onchocercose, Republic of the Congo; Institut de Recherche pour le Developpement Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials
Evaluating the effect of a behavioural intervention bundle on antibiotic use, quality of care, and household transmission of resistant Enterobacteriaceae in intervention versus control clusters in rural Burkina Faso and DR Congo (CABU-EICO)
DiscussionMost existing interventions aimed at improving antibiotic use focus on health care use, but in resource-limited settings, community use is highly prevalent. Previous studies targeting only providers failed to show an effect on antibiotic use. Evaluation will be done with before-after epidemiological measurements of actual prescriptions and use. If effective in reducing (Watch) antibiotic use, this would be an empowering methodology for communities, which has significant promise for long-term impact.Trial registrationClinicalTrials.govNCT05378880. 13 May 2022. (Source: Trials)
Source: Trials - January 27, 2024 Category: Research Source Type: clinical trials
Understanding context of violence against healthcare through citizen science and evaluating the effectiveness of a co-designed code of conduct and of a tailored de-escalation of violence training in Eastern Democratic Republic of Congo and Iraq: a study protocol for a stepped wedge randomized controlled trial
This study aims therefore to compare the effectiveness and cost-effectiveness of different interventions to reduce violence against HCWs in two post-crisis settings, providing valuable evidence for future efforts to address this issue.Trial registrationClinicalTrial.gov Identifier NCT05419687. Prospectively registered on June 15, 2022. (Source: Trials)
Source: Trials - December 19, 2023 Category: Research Source Type: clinical trials
Monkeypox, Biology, Outcome, Transmission and Epidemiology -Prospective Follow-up of High-risk Contacts
Conditions: Mpox Sponsors: Institute of Tropical Medicine, Belgium; Institut National de Recherche Biom édicale. Kinshasa, République Démocratique du Congo; National Institute of Allergy and Infectious Diseases (NIAID); Leidos Biomedical Research, Inc.; Alliance for International Medical Action; University of California, Los Angeles; Institut de Recherche pour le Developpement; University of Manito ba Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 16, 2023 Category: Research Source Type: clinical trials
Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo
Conditions: Uncomplicated Plasmodium Falciparum Malaria Interventions: Drug: Artesunate-amodiaquine; Drug: Artemether-lumefantrine Sponsors: Ministry of Public Health, Democratic Republic of the Congo; Centers for Disease Control and Prevention; Global Fund Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 10, 2023 Category: Research Source Type: clinical trials
Impact Study of Cholera Vaccination in Endemic Areas - Seroprevalence
Condition: Cholera Intervention: Sponsors: Epicentre; Wellcome Trust; Institut Pasteur; Institut National de Recherche Biomédicale. Goma, République Démocratique du Congo; Ministry of Public Health, Democratic Republic of the Congo; Medecins Sans Frontieres, France Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 26, 2023 Category: Research Source Type: clinical trials
