Screen and Treat Implementation for HAT Control
Conditions:   Sleeping Sickness;   Trypanosomiasis, African Intervention:   Other: Screen&treat Sponsors:   Institute of Tropical Medicine, Belgium;   Ministry of Public Health, Democratic Republic of the Congo;   Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo;   SANRU Asbl, Soins de Santé Primaires en Milieu Rural, République Démocratique du Congo;   Drugs for Neglected Diseases Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2022 Category: Research Source Type: clinical trials

Comparison of intermittent screening (using ultra-sensitive malaria rapid diagnostic test) and treatment (using a newly registered antimalarial pyronaridine-artesunate —PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas: ULTRAPYRAPREG
This study aims to compare the non-inferiority of ISTp using us-RDTs and Pyramax ® versus IPTp-SP on malaria in pregnancy through a randomized clinical trial performed in Kisenso, Kinshasa, the Democratic Republic of the Congo, a malaria perennial transmission area.DiscussionThe results will be essential for the National Malaria Control Program to update the malaria prevention policy in pregnant women in the Democratic Republic of the Congo.Trial registrationClinicalTrials.gov NCT04783051 (Source: Trials)
Source: Trials - November 28, 2022 Category: Research Source Type: clinical trials

Rotavirus vaccine clinical trials: a cross-sectional analysis of clinical trials registries
ConclusionsMapping rotavirus vaccine clinical trial activity using data from the WHO ICTRP beneficial provides valuable information on planned, ongoing, or completed trials for researchers, funders, and healthcare decision-makers. Despite the high rotavirus disease burden in low- and middle-income countries, including Africa, there is minimal clinical trial activity related to the condition on the continent. The clinical trial registries as a valuable tool to share interim results of the trials. (Source: Trials)
Source: Trials - November 17, 2022 Category: Research Source Type: clinical trials