Congenital Cystic Adenomatous Malformation (CCAM) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Prenatally Diagnosed Large Lung Lesions: Timing of Resection and Perinatal Outcomes
Fetuses with large lung lesions including congenital cystic adenomatoid malformations (CCAMs) are at risk for cardiopulmonary compromise. Prenatal maternal betamethasone and cyst drainage for micro- and macrocystic lesions respectively have improved outcomes yet some lesions remain large and require resection before birth (open fetal surgery, OFS), at delivery via an Ex Utero Intrapartum Treatment (EXIT), or immediately post cesarean section (section-to-resection, STR). We sought to compare prenatal characteristics and outcomes in fetuses undergoing OFS, EXIT, or STR to inform decision-making and prenatal counseling. (Sour...
Source: Journal of Pediatric Surgery - September 8, 2023 Category: Surgery Authors: Sourav K. Bose, John D. Stratigis, Nicholas Ahn, Jennifer Pogoriler, Holly L. Hedrick, Natalie E. Rintoul, Emily A. Partridge, Alan W. Flake, Nahla Khalek, Julianna Gebb, Christina Paidas Teefey, Shelly Soni, Ryoko Hamaguchi, Julie Moldenhauer, N. Scott A Source Type: research

Respiratory and Musculoskeletal Long-Term Outcomes after Surgical Resection of Congenital Cystic Adenomatoid Malformation of the Lung in Newborns, Infants, and Toddlers
Conclusions Patients operated for CCAML had good overall outcomes despite pulmonary symptoms and musculoskeletal sequelae. Even though these issues are frequently paucisymptomatic, trying to use less-invasive procedures (such as minimally axillary open “muscle-sparing” thoracotomy or thoracoscopy) may reduce this burden. A structured multidisciplinary FU is required. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 8, 2023 Category: Surgery Authors: Busti, Matteo Zarfati, Angelo Valfre, Laura Conforti, Andrea Bagolan, Pietro Tags: Original Article Source Type: research

Congenital pulmonary airway malformation in a 5 month old boy, complicated by pneumonia
AbstractCongenital cystic lesions of the lung are rare. The most common congenital anomaly among them, involving the lower respiratory tract, is congenital cystic adenomatoid malformation (CCAM), currently referred to as congenital pulmonary airway malformation (CPAM). They may be incidentally detected on prenatal or postnatal imaging. They usually present within two years of life, rarely in adults. CPAMs may be asymptomatic at birth. Some may opt for observation alone due to lack of evidence on the incidence of long-term complications. However, rarely has a CPAM remained asymptomatic throughout life and complications even...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - July 3, 2023 Category: Cardiovascular & Thoracic Surgery Source Type: research

Congenital cystic adenomatoid malformation of lung in adults: A report of 7 cases
Conclusion: Congenital cystic adenomatoid malformation is uncommon in adults. However, it must be included in the differential diagnoses of patients presenting with recurrent lung infections. In view of the malignant potential, surgical resection is recommended. (Source: European Respiratory Journal)
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Boubaker, N., Abdennadher, M., Zribi, H., Abdelkabir, A., Bouacida, I., Zairi, S., Ayadi, A., Ouerghi, S., Marghli, A., abdelkbir, A. Tags: 08.01 - Thoracic surgery Source Type: research

Management of Congenital Lung Malformations
This article will focus on the following malformations: congenital pulmonary airway malformations, formally known as congenital cystic adenomatoid malformations, bronchopulmonary sequestration, congenital lobar emphysema, and bronchogenic cyst. Each of these malformations will be defined and examined from an embryologic, pathophysiologic, and clinical management perspective unique to that specific lesion. A review of current recommendations in both medical and surgical management of these lesions will be discussed as well as widely accepted treatment algorithms. (Source: Clinics in Perinatology)
Source: Clinics in Perinatology - November 1, 2022 Category: Perinatology & Neonatology Authors: Brittany N. Hegde, KuoJen Tsao, Shinjiro Hirose Source Type: research

The long-term outcome following thoraco-amniotic shunting for congenital lung malformations
Congenital lung malformation (CLM) is an umbrella term used for a heterogenous group including congenital pulmonary airway malformations (CPAMs) (formerly congenital cystic adenomatoid malformation) [1], bronchopulmonary sequestrations (BPS), hybrid lesions, congenital pulmonary emphysema, segmental emphysema [2] and bronchogenic cysts. The current classification of CPAM, developed by Stocker [1], is based on resected surgical specimens and histological features. Therefore, it has obvious limitations when trying to apply it antenatally. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - October 23, 2022 Category: Surgery Authors: Ancuta Muntean, Ramona Cazacu, Niyi Ade-Ajayi, Shailesh B Patel, Kypros Nicolaides, Mark Davenport Source Type: research

Chest Wall Deformities and Congenital Lung Lesions: What the General/Thoracic Surgeon Should Know
Surg Clin North Am. 2022 Oct;102(5):883-911. doi: 10.1016/j.suc.2022.07.017. Epub 2022 Sep 13.ABSTRACTPectus excavatum, carinatum, and arcuatum are 3 developmental chest wall deformities that may evolve during childhood and cause cardiac and/or pulmonary compression. Evaluation may include nonsurgical subspecialty consultations and imaging studies. Treatment may be nonoperative or surgical. Long-term follow-up studies have identified rare complications of traditional open repair. Routine in utero ultrasonography has led to increasing identification of congenital lung anomalies, including congenital cystic adenomatoid malfo...
Source: The Surgical Clinics of North America - October 9, 2022 Category: Surgery Authors: J Duncan Phillips John David Hoover Source Type: research

Chest Wall Deformities and Congenital Lung Lesions
Pectus excavatum, carinatum, and arcuatum are 3 developmental chest wall deformities that may evolve during childhood and cause cardiac and/or pulmonary compression. Evaluation may include nonsurgical subspecialty consultations and imaging studies. Treatment may be nonoperative or surgical. Long-term follow-up studies have identified rare complications of traditional open repair. Routine in utero ultrasonography has led to increasing identification of congenital lung anomalies, including congenital cystic adenomatoid malformations, pulmonary sequestrations, and bronchogenic cysts. Short-term follow-up studies have suggeste...
Source: Surgical Clinics of North America - September 12, 2022 Category: Surgery Authors: J. Duncan Phillips, John David Hoover Source Type: research

Lambdoid Craniosynostosis in an Infant With Congenital Cystic Adenomatoid Malformation (CCAM)
Abstract: Both congenital cystic adenomatoid malformation (CCAM) and lambdoid craniosynostosis are exceedingly rare, with estimated incidences of around 1 in 30,000 live births for each. Herein, we present a case of a patient with prenatally diagnosed CCAM requiring 4 doses of prenatal steroids and ultimately thoracotomy with right lower lobectomy. The operation was uncomplicated, and genome-wide analysis of SNPs revealed no pathologic abnormalities. Development was normal until head shape changes were noted at 5 months of age at which point evaluation by a craniofacial surgeon and 3D CT imaging revealed left-sided lam...
Source: Journal of Craniofacial Surgery - July 1, 2022 Category: Surgery Tags: Clinical Studies Source Type: research

Congenital Cystic Adenomatoid Malformation in an Adult
Am J Med Sci. 2022 Apr 29:S0002-9629(22)00212-9. doi: 10.1016/j.amjms.2022.04.031. Online ahead of print.NO ABSTRACTPMID:35500662 | DOI:10.1016/j.amjms.2022.04.031 (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 2, 2022 Category: General Medicine Authors: Yanhua Sun Qinghua Cao Jun Li Source Type: research

Delivery planning for Congenital Lung Malformations: A CVR based perinatal care algorithm
Congenital lung malformations (CLM) represent a broad range of pathologies, including congenital cystic adenomatoid malformations, bronchopulmonary sequestrations, bronchial atresia, congenital lobar emphysema, and bronchogenic cysts. These lesions are increasingly detected in the prenatal period due to advances in ultrasound technology with an estimated incidence of approximately 4 per 10,000 live births.[1] After detection of a CLM, expectant mothers are monitored closely due to the variable nature of lesion growth. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - January 8, 2022 Category: Surgery Authors: Steven C. Mehl, Walker D. Short, Austin Kinley, Tim C. Lee, Raphael C. Sun, Michael A. Belfort, Alireza A. Shamshirsaz, Jimmy Espinoza, Roopali Donepudi, Magdalena Sanz-Cortes, Ahmed A. Nassr, Amy R. Mehollin-Ray, Sundeep G. Keswani, Alice King Source Type: research