Prenatally Diagnosed Large Lung Lesions: Timing of Resection and Perinatal Outcomes

Fetuses with large lung lesions including congenital cystic adenomatoid malformations (CCAMs) are at risk for cardiopulmonary compromise. Prenatal maternal betamethasone and cyst drainage for micro- and macrocystic lesions respectively have improved outcomes yet some lesions remain large and require resection before birth (open fetal surgery, OFS), at delivery via an Ex Utero Intrapartum Treatment (EXIT), or immediately post cesarean section (section-to-resection, STR). We sought to compare prenatal characteristics and outcomes in fetuses undergoing OFS, EXIT, or STR to inform decision-making and prenatal counseling.

Source: Journal of Pediatric Surgery - September 8, 2023 Category: Surgery Authors: Sourav K. Bose, John D. Stratigis, Nicholas Ahn, Jennifer Pogoriler, Holly L. Hedrick, Natalie E. Rintoul, Emily A. Partridge, Alan W. Flake, Nahla Khalek, Julianna Gebb, Christina Paidas Teefey, Shelly Soni, Ryoko Hamaguchi, Julie Moldenhauer, N. Scott A Source Type: research