Network-based identification of key proteins and repositioning of drugs for non-small cell lung cancer
CONCLUSION: Hence, there is a possibility of repurposing these drugs for the treatment of non-small-cell lung cancer.PMID:38600056 | DOI:10.1002/cnr2.2031 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Oluwatosin Maryam Adeyemo Zainab Ashimiyu-Abdusalam Mary Adewunmi Temitope Ayanfunke Ayano Muhammad Sohaib Reem Abdel-Salam Source Type: research

Sertaconazole 300 mg versus clotrimazole 500 mg vaginal suppository for treating pregnant women with acute vaginal candidiasis: a double-blinded, randomized trial
Vaginal candidiasis (VC) commonly affects pregnant women. Traditionally, clotrimazole vaginal tablets (CLO) have been the cornerstone of management. However, sertaconazole ovules (SER) offer a novel topical an... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 4, 2024 Category: OBGYN Authors: Chenchit Chayachinda, Manopchai Thamkhantho, Thanapa Rekhawasin and Chanakarn Klerdklinhom Tags: Research Source Type: research

Colorimetric detection of clotrimazole environmental pollutant using a newly developed chemosensor; an experimental and theoretical study
. (Source: International Journal of Environmental Analytical Chemistry)
Source: International Journal of Environmental Analytical Chemistry - April 1, 2024 Category: Chemistry Authors: Hossein TavallaliSara FakhraeeMina Dashti DarvishzadehMohammad Ali KarimiEisa RahimiDepartment of Chemistry, Payame Noor University, Tehran, Iran Source Type: research

Efficacy of 1% Clotrimazole Powder Monotherapy for Treating Tinea Cruris: A Comparative Randomized Study
CONCLUSION: Monotherapy with 1% clotrimazole powder showed comparable efficacy to 1% clotrimazole cream. Furthermore, the powder treatment reduced sweat more effectively compared to the cream.PMID:38554260 | DOI:10.1093/milmed/usae105 (Source: Military Medicine)
Source: Military Medicine - March 30, 2024 Category: International Medicine & Public Health Authors: Punyawee Ongsri Nanchaya Na Bangchang Phuwakorn Saengthong-Aram Charussri Leeyaphan Penvadee Pattanaprichakul Sumanas Bunyaratavej Source Type: research

Anti-fungal effects of novel N-(tert-butyl)-2-(pyridin-2-yl)imidazo[1,2-a]pyridin-3-amine derivative and it's in-vitro, in-silico, and mode of action against Candida spp
In this study, two newly synthesized imidazo[1,2-a]pyridine derivative (Probe I and Probe II) molecules were investigated for its antimicrobial potency against of a panel of bacterial (Gram-positive and Gram-negative bacteria) and fungal pathogens. Among the different types of pathogens, we found that Probe II showed excellent antifungal activity against fungal pathogens, based on the preliminary screening the potent molecule further investigated against multidrug-resistance Candida sp. (n = 10) and compared with commercial molecules. In addition, in-silico molecular docking, its dynamics, absorption, distribution, metabol...
Source: Archives of Microbiology - March 21, 2024 Category: Microbiology Authors: Manivannan Nandhagopal Ramanjaneyulu Mala Kanagasabai Somarathinam Divya Dhakshinamurthy Mathivanan Narayanasamy Priyadharshni Vijayan Manimuthu Mani Shankar Source Type: research

Anti-fungal effects of novel N-(tert-butyl)-2-(pyridin-2-yl)imidazo[1,2-a]pyridin-3-amine derivative and it's in-vitro, in-silico, and mode of action against Candida spp
In this study, two newly synthesized imidazo[1,2-a]pyridine derivative (Probe I and Probe II) molecules were investigated for its antimicrobial potency against of a panel of bacterial (Gram-positive and Gram-negative bacteria) and fungal pathogens. Among the different types of pathogens, we found that Probe II showed excellent antifungal activity against fungal pathogens, based on the preliminary screening the potent molecule further investigated against multidrug-resistance Candida sp. (n = 10) and compared with commercial molecules. In addition, in-silico molecular docking, its dynamics, absorption, distribution, metabol...
Source: Archives of Microbiology - March 21, 2024 Category: Microbiology Authors: Manivannan Nandhagopal Ramanjaneyulu Mala Kanagasabai Somarathinam Divya Dhakshinamurthy Mathivanan Narayanasamy Priyadharshni Vijayan Manimuthu Mani Shankar Source Type: research

Effect of Clotrimazole Suppositories on Distribution of Pathogens in Vaginal Secretions and Oxidative Stress in Patients with Vaginitis
CONCLUSION: Clotrimazole suppositories have been shown to significantly enhance therapeutic outcomes for patients with vaginitis by alleviating inflammation, rebalancing vaginal microecology, regulating hormone secretion, and mitigating oxidative stress.PMID:38430151 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Jin Gao Source Type: research

Effect of Clotrimazole Suppositories on Distribution of Pathogens in Vaginal Secretions and Oxidative Stress in Patients with Vaginitis
CONCLUSION: Clotrimazole suppositories have been shown to significantly enhance therapeutic outcomes for patients with vaginitis by alleviating inflammation, rebalancing vaginal microecology, regulating hormone secretion, and mitigating oxidative stress.PMID:38430151 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Jin Gao Source Type: research

Effect of Clotrimazole Suppositories on Distribution of Pathogens in Vaginal Secretions and Oxidative Stress in Patients with Vaginitis
CONCLUSION: Clotrimazole suppositories have been shown to significantly enhance therapeutic outcomes for patients with vaginitis by alleviating inflammation, rebalancing vaginal microecology, regulating hormone secretion, and mitigating oxidative stress.PMID:38430151 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Jin Gao Source Type: research

Effect of Clotrimazole Suppositories on Distribution of Pathogens in Vaginal Secretions and Oxidative Stress in Patients with Vaginitis
CONCLUSION: Clotrimazole suppositories have been shown to significantly enhance therapeutic outcomes for patients with vaginitis by alleviating inflammation, rebalancing vaginal microecology, regulating hormone secretion, and mitigating oxidative stress.PMID:38430151 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Jin Gao Source Type: research

Effect of Clotrimazole Suppositories on Distribution of Pathogens in Vaginal Secretions and Oxidative Stress in Patients with Vaginitis
CONCLUSION: Clotrimazole suppositories have been shown to significantly enhance therapeutic outcomes for patients with vaginitis by alleviating inflammation, rebalancing vaginal microecology, regulating hormone secretion, and mitigating oxidative stress.PMID:38430151 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Jin Gao Source Type: research

Effect of Clotrimazole Suppositories on Distribution of Pathogens in Vaginal Secretions and Oxidative Stress in Patients with Vaginitis
CONCLUSION: Clotrimazole suppositories have been shown to significantly enhance therapeutic outcomes for patients with vaginitis by alleviating inflammation, rebalancing vaginal microecology, regulating hormone secretion, and mitigating oxidative stress.PMID:38430151 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 2, 2024 Category: Complementary Medicine Authors: Jin Gao Source Type: research