Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol + water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol + water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol + water and fitted t...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: Arshin Nemati Homa Rezaei Kader Poturcu Jalal Hanaee Abolghasem Jouyban Hongkun Zhao Elaheh Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol + water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol + water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol + water and fitted t...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: Arshin Nemati Homa Rezaei Kader Poturcu Jalal Hanaee Abolghasem Jouyban Hongkun Zhao Elaheh Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Effect of temperature and propylene glycol as a cosolvent on dissolution of clotrimazole
Ann Pharm Fr. 2022 Oct 14:S0003-4509(22)00142-0. doi: 10.1016/j.pharma.2022.10.001. Online ahead of print.ABSTRACTHerein, the solubility study of clotrimazole was performed in a propylene glycol+water system. The solubility values were fitted to various cosolvency equations. The model accuracies were studied with the computation of the mean relative deviations. The thermodynamic behavior was investigated according to the van't Hoff and Gibbs equations for clotrimazole in the propylene glycol+water system. Furthermore, the density data for clotrimazole were determined in mixtures of propylene glycol+water and fitted to the ...
Source: Annales Pharmaceutiques Francaises - October 17, 2022 Category: Drugs & Pharmacology Authors: A Nemati H Rezaei K Poturcu J Hanaee A Jouyban H Zhao E Rahimpour Source Type: research

Trichomoniasis refractory to 5-nitroimidazole therapy in Trinidad
We present such a case which was eventually treated with a low-cost intravaginal combination of boric acid and clotrimazole cream.PMID:36214266 | DOI:10.1177/00494755221131370 (Source: Tropical Doctor)
Source: Tropical Doctor - October 10, 2022 Category: Tropical Medicine Authors: Robert Jeffrey Edwards Miriam Parboo Jonathan Edwards Gregory Boyce Source Type: research

Trichomoniasis refractory to 5-nitroimidazole therapy in Trinidad
We present such a case which was eventually treated with a low-cost intravaginal combination of boric acid and clotrimazole cream.PMID:36214266 | DOI:10.1177/00494755221131370 (Source: Tropical Doctor)
Source: Tropical Doctor - October 10, 2022 Category: Tropical Medicine Authors: Robert Jeffrey Edwards Miriam Parboo Jonathan Edwards Gregory Boyce Source Type: research

Trichomoniasis refractory to 5-nitroimidazole therapy in Trinidad
We present such a case which was eventually treated with a low-cost intravaginal combination of boric acid and clotrimazole cream.PMID:36214266 | DOI:10.1177/00494755221131370 (Source: Tropical Doctor)
Source: Tropical Doctor - October 10, 2022 Category: Tropical Medicine Authors: Robert Jeffrey Edwards Miriam Parboo Jonathan Edwards Gregory Boyce Source Type: research

High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections
Sci Data. 2022 Oct 8;9(1):610. doi: 10.1038/s41597-022-01733-4.ABSTRACTViruses are genetically and structurally diverse, and outnumber cells by orders of magnitude. They can cause acute and chronic infections, suppress, or exacerbate immunity, or dysregulate survival and growth of cells. To identify chemical agents with pro- or antiviral effects we conducted arrayed high-content image-based multi-cycle infection screens of 1,280 mainly FDA-approved compounds with three human viruses, rhinovirus (RV), influenza A virus (IAV), and herpes simplex virus (HSV) differing in genome organization, composition, presence of an envelo...
Source: Herpes - October 8, 2022 Category: Infectious Diseases Authors: Dominik Olszewski Fanny Georgi Luca Murer Vardan Andriasyan Fabien Kuttler Anthony Petkidis Robert Witte Artur Yakimovich Lucy Fischer Alina Rozanova Yohei Yamauchi Gerardo Turcatti Urs F Greber Source Type: research

Treatment of otomycosis with clotrimazole: results accordingly with the fungus isolated
CONCLUSIONS: Otomycosis was more frequently caused by Candida, and this type of otomycosis is treated faster with clotrimazole 10 mg/dL plus ear cleaning, when compared with otomycosis by Aspergillus.SIGNIFICANCE: If otomycosis causative agent is identified or suspected, a prediction of the time needed till the resolution of otomycosis can be made, when clotrimazole ear drops are used.PMID:36128634 | DOI:10.1080/00016489.2022.2117845 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - September 21, 2022 Category: ENT & OMF Authors: Joselina Antunes Nuno Mendes Cristina Ad ónis Filipe Freire Source Type: research