An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
We present an 18-year-old man with extensive verrucous plaques in one knee interpreted by clinic, epidemiology, and biopsy as verrucous cutaneous leishmaniasis. He was treated with Glucantime® for 20 days without improvement. A new biopsy was made that was also interpreted as cutaneous leishmaniasis. The revision of both biopsies showed inflammation with abscessed granulomas and asteroid sporotrichotic bodies at the center of the granulomas that led to the diagnosis of sporotrichosis later confirmed by the fungus culture. The patient responded to the treatment with itraconazole. As clinical and epidemiological findings of...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Paola Mac ías Juliana Ord óñez Claudia M Arenas Gerza ín Rodríguez Source Type: research
An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
We present an 18-year-old man with extensive verrucous plaques in one knee interpreted by clinic, epidemiology, and biopsy as verrucous cutaneous leishmaniasis. He was treated with Glucantime® for 20 days without improvement. A new biopsy was made that was also interpreted as cutaneous leishmaniasis. The revision of both biopsies showed inflammation with abscessed granulomas and asteroid sporotrichotic bodies at the center of the granulomas that led to the diagnosis of sporotrichosis later confirmed by the fungus culture. The patient responded to the treatment with itraconazole. As clinical and epidemiological findings of...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Paola Mac ías Juliana Ord óñez Claudia M Arenas Gerza ín Rodríguez Source Type: research
An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
We present an 18-year-old man with extensive verrucous plaques in one knee interpreted by clinic, epidemiology, and biopsy as verrucous cutaneous leishmaniasis. He was treated with Glucantime® for 20 days without improvement. A new biopsy was made that was also interpreted as cutaneous leishmaniasis. The revision of both biopsies showed inflammation with abscessed granulomas and asteroid sporotrichotic bodies at the center of the granulomas that led to the diagnosis of sporotrichosis later confirmed by the fungus culture. The patient responded to the treatment with itraconazole. As clinical and epidemiological findings of...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Paola Mac ías Juliana Ord óñez Claudia M Arenas Gerza ín Rodríguez Source Type: research
An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
We present an 18-year-old man with extensive verrucous plaques in one knee interpreted by clinic, epidemiology, and biopsy as verrucous cutaneous leishmaniasis. He was treated with Glucantime® for 20 days without improvement. A new biopsy was made that was also interpreted as cutaneous leishmaniasis. The revision of both biopsies showed inflammation with abscessed granulomas and asteroid sporotrichotic bodies at the center of the granulomas that led to the diagnosis of sporotrichosis later confirmed by the fungus culture. The patient responded to the treatment with itraconazole. As clinical and epidemiological findings of...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Paola Mac ías Juliana Ord óñez Claudia M Arenas Gerza ín Rodríguez Source Type: research
Effect of melanin biosynthesis inhibition in the antifungal susceptibility of chromoblastomycosis agents
Antimicrob Agents Chemother. 2021 May 10:AAC.00546-21. doi: 10.1128/AAC.00546-21. Online ahead of print.ABSTRACTChromoblastomycosis (CBM) is a chronic subcutaneous infection caused by genera of melanized fungi: Fonsecaea, Cladophialophora, Phialophora, Exophiala and Rhinocladiella Melanin is a virulence factor known to influence antifungal susceptibility. A specific inhibitor of melanin biosynthesis is tricyclazole. The aim of this study was to evaluate the effect of melanin inhibition on antifungal susceptibility of chromoblastomycosis agents and describe the susceptibility profile of some unusual CBM agents. Seventy-six ...
Source: Antimicrobial Agents and Chemotherapy - May 11, 2021 Category: Microbiology Authors: Daiane Heidrich Danielle Machado Pagani Alessandra Koehler Karine de Oliveira Alves Maria L úcia Scroferneker Source Type: research
Effect of melanin biosynthesis inhibition in the antifungal susceptibility of chromoblastomycosis agents
Antimicrob Agents Chemother. 2021 May 10:AAC.00546-21. doi: 10.1128/AAC.00546-21. Online ahead of print.ABSTRACTChromoblastomycosis (CBM) is a chronic subcutaneous infection caused by genera of melanized fungi: Fonsecaea, Cladophialophora, Phialophora, Exophiala and Rhinocladiella Melanin is a virulence factor known to influence antifungal susceptibility. A specific inhibitor of melanin biosynthesis is tricyclazole. The aim of this study was to evaluate the effect of melanin inhibition on antifungal susceptibility of chromoblastomycosis agents and describe the susceptibility profile of some unusual CBM agents. Seventy-six ...
Source: Antimicrobial Agents and Chemotherapy - May 11, 2021 Category: Microbiology Authors: Daiane Heidrich Danielle Machado Pagani Alessandra Koehler Karine de Oliveira Alves Maria L úcia Scroferneker Source Type: research
