Chromoblastomycosis and sporotrichosis, two endemic but neglected fungal infections in Madagascar
Publication date: Available online 25 August 2017 Source:Journal de Mycologie Médicale / Journal of Medical Mycology Author(s): T. Rasamoelina, O. Raharolahy, N. Rakotozandrindrainy, I. Ranaivo, M. Andrianarison, B. Rakotonirina, D. Maubon, F.A. Rakotomalala, M. Rakoto Andrianarivelo, A. Andriantsimahavandy, F. Rapelanoro Rabenja, L.S. Ramarozatovo, M. Cornet Chromoblastomycosis and sporotrichosis are endemic fungal infections of tropical and subtropical regions, including Madagascar. The causal fungi develop in the soil or on plants and infect humans through wounds, either directly (wounding by the plant, ...
Source: Journal of Medical Mycology - August 26, 2017 Category: Biology Source Type: research

Chromoblastomycosis in India: Review of 169 cases
by Reshu Agarwal, Gagandeep Singh, Arnab Ghosh, Kaushal Kumar Verma, Mragnayani Pandey, Immaculata Xess Chromoblastomycosis (CBM) is a chronic, progressive, cutaneous and subcutaneous fungal infection following the traumatic implantation of certain dematiaceous fungi. The disease has worldwide prevalence with predominant cases reported from humid tropical and subtropical regions of America, Asia, an d Africa. Diagnosis is often delayed or misdirected either due to poor degree of clinical suspicions or clinical simulation of dermatological conditions. The infection is not uncommon in India and several case reports from the...
Source: PLoS Neglected Tropical Diseases - August 3, 2017 Category: Tropical Medicine Authors: Reshu Agarwal Source Type: research

[Series] Neglected endemic mycoses
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease. After traumatic cutaneous inoculation, several fungi can cause neglected mycoses such as sporotrichosis, chromoblastomycosis, mycetoma, entomophthoramycosis, and lacaziosis. Most of these diseases have a subacute to chronic course and they can become recalcitrant to therapy and lead to physical disabilities, including inabili...
Source: The Lancet Infectious Diseases - July 31, 2017 Category: Infectious Diseases Authors: Flavio Queiroz-Telles, Ahmed Hassan Fahal, Diego R Falci, Diego H Caceres, Tom Chiller, Alessandro C Pasqualotto Tags: Series Source Type: research

Study on the organization of cellular elements in the granulomatous lesion caused by chromoblastomycosis
ConclusionsThe results indicated that the granuloma present in the cutaneous lesion of chromoblastomycosis is the mixed organized mycotic granuloma with high expression of the cellular components. (Source: Journal of Cutaneous Pathology)
Source: Journal of Cutaneous Pathology - July 28, 2017 Category: Pathology Authors: Renan Minotto, Maria Isabel Albano Edelweiss, Maria L úcia Scroferneker Tags: ORIGINAL ARTICLE Source Type: research

Subcutaneous mycoses in Peru: a systematic review and meta ‐analysis for the burden of disease
ConclusionsSporotrichosis is the most common subcutaneous mycosis in Peru, with a high disease burden in Apurimac. Chromoblastomycosis, lobomycosis, and subcutaneous phaeohyphomycosis are rare mycoses in Peru. (Source: International Journal of Dermatology)
Source: International Journal of Dermatology - July 1, 2017 Category: Dermatology Authors: Max Carlos Ram írez Soto, German Malaga Tags: Tropical Medicine Rounds Source Type: research

Chromoblastomycosis caused by Cladophialophora carrionii
Jiaoqing Tang, Kaiwen Zhuang, Xin Ran, Yaling Dai, Yuping RanIndian Journal of Dermatology, Venereology, and Leprology 2017 83(4):482-485 (Source: Indian Journal of Dermatology, Venereology and Leprology)
Source: Indian Journal of Dermatology, Venereology and Leprology - June 5, 2017 Category: Dermatology Authors: Jiaoqing Tang Kaiwen Zhuang Xin Ran Yaling Dai Yuping Ran Source Type: research

Counterfeit Pennies: Distinguishing Chromoblastomycosis From Phaeohyphomycotic Infections
No abstract available (Source: The American Journal of Dermatopathology)
Source: The American Journal of Dermatopathology - May 20, 2017 Category: Pathology Tags: Letters to the Editor Source Type: research

GSE84257 Modulation of the inflammatory response by dematiaceous fungal morphotypes and its impact on inflammatory response chronicity
Conclusions: Our findings reveal two different fungal-host interaction strategies according to fungal form, highlighting fungal dimorphism as an important key in understanding the bipolar nature of inflammatory response in fungal infections (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - May 1, 2017 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

Squamous cell carcinoma in long-standing chromoblastomycosis
Prasenjeet Mohanty, K Vivekanandh, Liza Mohapatra, Gaurav DashIndian Journal of Dermatology, Venereology, and Leprology 2017 83(3):363-365 (Source: Indian Journal of Dermatology, Venereology and Leprology)
Source: Indian Journal of Dermatology, Venereology and Leprology - April 24, 2017 Category: Dermatology Authors: Prasenjeet Mohanty K Vivekanandh Liza Mohapatra Gaurav Dash Source Type: research

Unique case report of a chromomycosis and Listeria in soft tissue and cerebellar abscesses after kidney transplantation
Chromomycosis is a rare mycotic infection encountered in tropical and subtropical regions. The disease presents as a slowly-evolving nodule that can become infected with bacteria. Here, we describe a unique as... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 20, 2017 Category: Infectious Diseases Authors: J. Tourret, N. Benabdellah, S. Drouin, F. Charlotte, J. Rottembourg, N. Arzouk, A. Fekkar and B. Barrou Source Type: research

Chromoblastomycosis caused by Rhinocladiella similis: case report
This report presents R. similis as a new agent of chromoblastomycosis and raises the hypothesis that this species could be more resistant to some antifungals than R. aquaspersa. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - April 11, 2017 Category: Biology Source Type: research

[Chromomycosis acquired in a non-tropical area: A case report].
DISCUSSION: The possibility of acquiring chromomycosis other than in a tropical zone is slight but has nevertheless been described, particularly in Eastern Europe. In our patient, the exact source of contamination is unknown, although it may have been acquired through frequent horse-riding or use of saunas. This case confirms the efficacy of combined itraconazole and terbinafine against this condition, which is usually difficult to treat. PMID: 28396061 [PubMed - as supplied by publisher] (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - April 7, 2017 Category: Dermatology Authors: Ouédraogo MS, Vignon-Pennamen MD, Battistella M, Levy A, Feuilhade de Chauvin M, Petit A Tags: Ann Dermatol Venereol Source Type: research

Chromomycosis, an unusual cause of cicatricial ectropion: a case report
We report the case of a 50-year-old male patient who was a rural worker and had been treated without success for three decades. Facial lesions progressed and caused severe cicatricial retraction. As the infection evolved, the left upper eyelid developed cicatricial ectropion. The surgical treatment was performed using skin obtained from the patient's own abdomen. Patient has developed a good postoperative appearanceRESUMO A cromomicose é uma infecção fúngica que afeta a epiderme, derme e tecido subcutâneo. A infecção é causada por espécies de fungo dematiáceos que se coram em preto. Nós relatamos o caso de um ho...
Source: Arquivos Brasileiros de Oftalmologia - March 30, 2017 Category: Opthalmology Source Type: research

Modulation of the immune response by < i > Fonsecaea pedrosoi < /i > morphotypes in the course of experimental chromoblastomycosis and their role on inflammatory response chronicity
In this study we show that hyphae and muriform cells are able to establish a murine CBM with skin lesions and histopathological aspects similar to that found in humans, with muriform cells being the most persistent fungal form, whereas mice infected with conidia do not reach the chronic phase of the disease. Moreover, in injured tissue the presence of hyphae and especially muriform cells, but not conidia, is correlated with intense production of pro-inflammatory cytokinesin vivo. High-throughput RNA sequencing analysis (RNA-Seq) performed at early time points showed a strong up-regulation of genes related to fungal recogni...
Source: PLoS Neglected Tropical Diseases - March 29, 2017 Category: Tropical Medicine Authors: Isaque Medeiros Siqueira Source Type: research

Exploring the genomic diversity of black yeasts and relatives (Chaetothyriales, Ascomycota).
lmayr H, Moussa TA, Gorbushina A, Felipe MS, Cuomo CA, de Hoog GS Abstract The order Chaetothyriales (Pezizomycotina, Ascomycetes) harbours obligatorily melanised fungi and includes numerous etiologic agents of chromoblastomycosis, phaeohyphomycosis and other diseases of vertebrate hosts. Diseases range from mild cutaneous to fatal cerebral or disseminated infections and affect humans and cold-blooded animals globally. In addition, Chaetothyriales comprise species with aquatic, rock-inhabiting, ant-associated, and mycoparasitic life-styles, as well as species that tolerate toxic compounds, suggesting a high...
Source: Studies in Mycology - March 1, 2017 Category: Biology Authors: Teixeira MM, Moreno LF, Stielow BJ, Muszewska A, Hainaut M, Gonzaga L, Abouelleil A, Patané JS, Priest M, Souza R, Young S, Ferreira KS, Zeng Q, da Cunha MM, Gladki A, Barker B, Vicente VA, de Souza EM, Almeida S, Henrissat B, Vasconcelos AT, Deng S, Vog Tags: Stud Mycol Source Type: research