Chromoblastomycosis presenting with sporotrichoid distribution and bony destruction: A rare presentation
Angoori Gnaneshwar Rao, Naresh Marepally, V SVN Sindhu, Sreeja Vangala, Sindhuja Bujagouni, Pranaya Boppireddy, Shireesha Koolla, Anmisha Bandaru, Srujana Ankam, Bhavita BadeIndian Journal of Dermatology 2023 68(4):450-454
Chromoblastomycosis (CBM) presenting with linear distribution and with underlying bony destruction is rare. Herein, we report such a presentation in a farmer who presented with ulcerated nodules over the right leg and swelling of the right foot. Potassium hydroxide (KOH) preparation and histopathological examination of biopsy from nodule revealed characteristic sclerotic bodies on Gomori methenamine sil...
Source: Indian Journal of Dermatology - August 31, 2023 Category: Dermatology Authors: Angoori Gnaneshwar Rao Naresh Marepally V SVN Sindhu Sreeja Vangala Sindhuja Bujagouni Pranaya Boppireddy Shireesha Koolla Anmisha Bandaru Srujana Ankam Bhavita Bade Source Type: research
Scientific literature on neglected tropical diseases: a bibliometric analysis
Pathog Glob Health. 2023 Aug 22:1-8. doi: 10.1080/20477724.2023.2250619. Online ahead of print.ABSTRACTNeglected tropical diseases (NTDs) are a group of diseases mainly affecting people in low- and middle-income Countries. The aim of this study was to perform a bibliometric analysis of the scientific literature on NTDs. Using the MeSH database, we quantified the number of publications on MEDLINE targeting each NTD, which were published from 1 January 1999 to 31 January 2019. In order to weight the number of publications targeting a given NTD according to the total number of publications/year, we calculated a Yearly Publica...
Source: Pathogens and Global Health - August 22, 2023 Category: International Medicine & Public Health Authors: Gianpiero Tebano Elisa Vanino Paolo Muratori Francesco Cristini Source Type: research
Diagnostic capacities and treatment practices on implantation mycoses: Results from the 2022 WHO global online survey
by Barbara Milani, Daniel Argaw Dagne, Hye Lynn Choi, Marco Schito, Heather Anne Stone
Between January and March 2022, WHO conducted a global online survey to collect data on diagnostic capacities and treatment practices in different settings for four implantation mycoses: eumycetoma, actinomycetoma, cutaneous sporotrichosis and chromoblastomycosis. The survey investigated the type of diagnostic methods available in countries at various health system levels (tertiary, secondary, primary level) and the medicines used to treat implantation mycoses, with a view to understanding the level of drug repurposing for treatment of ...
Source: PLoS Neglected Tropical Diseases - June 28, 2023 Category: Tropical Medicine Authors: Barbara Milani Source Type: research
Subcutaneous phaeohyphomycosis caused by Alternaria section Alternaria
The dematiaceous fungal infection may cause a variety of clinical diseases. Once fungal organisms are introduced into the dermis, the clinical presentation may change based on the patient's immunity status [1]. Some dematiaceous fungi transition from their native filamentous and hyphal form to become rounded, septate, and pigmented spores that are known as sclerotic cells. This results in a chronic condition that is called chromoblastomycosis, which is usually observed in immunocompetent people. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - May 31, 2023 Category: Infectious Diseases Authors: Xiujiao Xia, Zehu Liu, Hong Shen Source Type: research
Bacterial, fungal and parasitic co-infections in leprosy: A scoping review
ConclusionWe observed a male-dominated pattern of co-infections among working-age individuals with multibacillary leprosy. Unlike prior studies reporting increased leprosy reactions in chronic viral co-infections, our findings did not indicate any increase among bacterial, fungal, or parasitic co-infections. Rather, co-infections with tuberculosis and leishmaniasis appeared to reduce leprosy reactions. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - May 22, 2023 Category: Tropical Medicine Authors: Luis Alberto Ribeiro Fr óes Jr Source Type: research
An Experimental Model of Chromoblastomycosis Caused by Fonsecaea sp. Species
Methods Mol Biol. 2023;2667:129-138. doi: 10.1007/978-1-0716-3199-7_10.ABSTRACTThe experimental rodent models for the fungal disease are a handy tool for understanding host-fungus interactions. To Fonsecaea sp., one of the causative agents of chromoblastomycosis, there is an extra challenge because the animals preferably used show a spontaneous cure; so until now, there is no model to reproduce the long-term disease similar to human chronic disease. In this chapter, we described an experimental model using rats and mice with a subcutaneous route, with the checkpoints of acute-like and chronic-like lesion analysis comparabl...
Source: Mol Biol Cell - May 5, 2023 Category: Molecular Biology Authors: Anamelia L Bocca Isaque Medeiros Siqueira Source Type: research
An Experimental Model of Chromoblastomycosis Caused by Fonsecaea sp. Species
Methods Mol Biol. 2023;2667:129-138. doi: 10.1007/978-1-0716-3199-7_10.ABSTRACTThe experimental rodent models for the fungal disease are a handy tool for understanding host-fungus interactions. To Fonsecaea sp., one of the causative agents of chromoblastomycosis, there is an extra challenge because the animals preferably used show a spontaneous cure; so until now, there is no model to reproduce the long-term disease similar to human chronic disease. In this chapter, we described an experimental model using rats and mice with a subcutaneous route, with the checkpoints of acute-like and chronic-like lesion analysis comparabl...
Source: Mol Biol Cell - May 5, 2023 Category: Molecular Biology Authors: Anamelia L Bocca Isaque Medeiros Siqueira Source Type: research
Chromoblastomycosis: delayed diagnosis with extensive cutaneous lesions
Chromoblastomycosis (CBM) is a chronic cutaneous mycosis caused by the implantation of brown-pigmented fungi, primarily Fonsecaea species. It is a neglected tropical disease affecting impoverished populations in the tropics [1,2]. The clinical appearance of CBM is often polymorphic, with at least five different forms: nodular, tumoral, verrucous, plaque, and scarified; resulting in misdiagnosis or delayed diagnosis. A delayed diagnosis leads to chronic lymphedema, ankylosis, antifungal resistance, and in rare cases transformation into squamous cell carcinoma [3,4]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - March 25, 2023 Category: Infectious Diseases Authors: Wubshet Assefa, Rahel Sinatayehu, Mathias Amare Sendeku, Melaku Dires Tags: Medical Imagery Source Type: research
Chromoblastomycosis:Delayed diagnosis with an extensive cutaneous lesions
Chromoblastomycosis (CBM) is a chronic cutaneous mycosis caused by an implantation of brown-pigmented fungi, primarily Fonsecaea species. It is a Neglected Tropical Disease affecting impoverished populations in the tropics [1, 2]. The clinical appearance of CBM is often polymorphic, with at least five different forms: nodular, tumoral, verrucous, plaque, and scarified; resulting in misdiagnosis or delayed diagnosis. When a diagnosis is delayed, leads to chronic lymphedema, ankylosis, antifungal resistance, and in rare cases transformation into squamous cell carcinoma [3, 4].Thus early identification of the pathogens throug...
Source: International Journal of Infectious Diseases - March 25, 2023 Category: Infectious Diseases Authors: Wubshet Assefa, Rahel Sinatayehu, Mathias Amare Sendeku, Melaku Dires Tags: Medical Imagery Source Type: research
A rare case of chromoblastomycosis presenting as a primary ulcer
Subhra Dhar, Divya Gupta, Rajib Malakar, Sandipan DharIndian Journal of Dermatology 2022 67(5):560-562 (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - December 29, 2022 Category: Dermatology Authors: Subhra Dhar Divya Gupta Rajib Malakar Sandipan Dhar Source Type: research
A Variety of Fungal Species on the Green Frogs' Skin (Pelophylax esculentus complex) in South Banat
Microb Ecol. 2022 Nov 2. doi: 10.1007/s00248-022-02135-0. Online ahead of print.ABSTRACTIn the last several decades, amphibian populations have been declining worldwide. Many factors have been linked to global amphibian decline, including habitat destruction, pollution, introduced species, global environmental changes, and emerging infectious diseases. Recent studies of amphibian skin infections were mainly focused on the presence of chytridiomycosis, neglecting other members of the frogs' skin communities. The diversity pattern of fungal dwellers on the skin of green frogs (Pelophylax esculentus complex) was investigated....
Source: Microbial Ecology - November 2, 2022 Category: Microbiology Authors: Milo š Stupar Željko Savković Katarina Breka Sr đan Stamenković Imre Krizmani ć Jelena Vukojevi ć Milica Ljaljevi ć Grbić Source Type: research
