Immune response in human chromoblastomycosis and eumycetoma – focusing on human interleukin‐17A, interferon‐gamma, tumour necrosis factor‐alpha, interleukin‐1 beta and human beta‐defensin‐2
This study demonstrated IL‐17A expression in human eumycetoma and HBD‐2 expression in human chromoblastomycosis for the first time. However, their role in immune response remains to be elucidated. (Source: Mycoses)
Source: Mycoses - June 30, 2016 Category: Research Authors: Charussri Leeyaphan, Carren Hau, Shintaro Takeoka, Yayoi Tada, Sumanas Bunyaratavej, Penvadee Pattanaprichakul, Panitta Sitthinamsuwan, Angkana Chaiprasert, Yuko Sasajima, Koichi Makimura, Shinichi Watanabe Tags: Original Article Source Type: research
A case of chromoblastomycosis by Fonsecaea nubica indicating a possible insect route of transmission
Summary
A first auricular case of chromoblastomycosis due to Fonsecaea nubica is reported in a 42‐year‐old Chinese male. He presented a slightly verrucous, erythematous plaque on his right auricle which had gradually extended over a 10‐year period, and the patient reported a history of dog flea sting before onset of the lesions. Diagnosis was based on histopathological and mycological examination of clinical samples, which revealed muriform cells. Identification of the aetiological agent was assessed by morphological characteristics and confirmed at species level by sequencing of the rDNA internal transcribed spacer ...
Source: Mycoses - June 21, 2016 Category: Research Authors: Yingdan Chen, Songchao Yin, Meirong Li, Rongzhang Chen, Ling Wei, Han Ma, Shuwen Deng, Gert Sybren de Hoog, Wei Lai, Chun Lu, Peiying Feng Tags: Case Report Source Type: research
Chromoblastomycosis and sporotrichosis in Madagascar : Epidemiology, molecular diagnostic and perspectives
Conclusion These results confirmed that CBM and SP persist at a high frequency in Madagascar. The availability of a reliable PCR tool in routine and the clinical expertise gained during this study will help the national authorities to set up a proper control and prevention program. An environmental survey is planned to describe the spread of the causative agents in the environment in an attempt to prevent the contamination. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 17, 2016 Category: Biology Source Type: research
Chromoblastomycosis and sporotrichosis in Madagascar : Epidemiology, molecular diagnostic and perspectives
Conclusion These results confirmed that CBM and SP persist at a high frequency in Madagascar. The availability of a reliable PCR tool in routine and the clinical expertise gained during this study will help the national authorities to set up a proper control and prevention program. An environmental survey is planned to describe the spread of the causative agents in the environment in an attempt to prevent the contamination. (Source: Journal of Medical Mycology)
Source: Journal of Medical Mycology - June 14, 2016 Category: Biology Source Type: research
Two cases of axillary chromoblastomycosis
Sowmyashree Krishna, Manjunath M Shenoy, Malcolm Pinto, Varsha SaxenaIndian Journal of Dermatology, Venereology, and Leprology 2016 82(4):455-456 (Source: Indian Journal of Dermatology, Venereology and Leprology)
Source: Indian Journal of Dermatology, Venereology and Leprology - June 5, 2016 Category: Dermatology Authors: Sowmyashree KrishnaManjunath M ShenoyMalcolm PintoVarsha Saxena Source Type: research
Chromoblastomycosis associated with bone and central nervous involvement system in an immunocompetent child caused by exophiala spinifera
We report a 12-year-old immunocompetent male child diagnosed with chromoblastomycosis on the lower leg, who in a span of few months developed osteomyelitis and left hemiparesis. Fungal culture showed growth of Exophiala spinifera. Child showed good improvement with voriconazole and itraconazole after 1 year of treatment. Skin lesions healed with minimal scarring and his power improved. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - May 12, 2016 Category: Dermatology Authors: Sahana M SrinivasVykuntaraju K GowdaS MahanteshRajeshwari MannapurSanjay K Shivappa Source Type: research
Corrigendum to “First case of chromoblastomycosis from Bangladesh” [Med. Mycol. Case Rep. 10 (2015) 1–3]
Publication date: March 2016 Source:Medical Mycology Case Reports, Volume 11 Author(s): Sophie Brun, Coralie Zumelzu, Mai Ba Hoanganh, Annie Levy, Dea Garcia-Hermoso, Liliane Laroche, Arezki Izri (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - May 10, 2016 Category: Biology Source Type: research
Chromoblastomycosis due to Fonsecaea monophora misdiagnosed as sporotrichosis and cutaneous tuberculosis in a pulmonary tuberculosis patient
We report a case of chromoblastomycosis in a pulmonary tuberculosis patient without known history of trauma. The lesions were initially diagnosed as sporotrichosis and skin tuberculosis. Histopathology of scales and skin biopsy specimen revealed sclerotic bodies, the hallmark of chromoblastomycosis. The causative organism was identified as Fonsecaea monophora by rDNA ITS sequencing. The lesions recovered markedly after two month treatment with oral terbinafine 250mg daily according to drug sensitive test in vitro in combination with local thermotherapy (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - May 10, 2016 Category: Biology Source Type: research
Disseminated phaeohyphomycosis presenting as chromoblastomycosis in an immunocompetent host: A rare manifestation
We report a case of disseminated phaeohyphomycosis caused by E.spinifera in a 52-year-old woman without evidence of immunodeficiency presenting with clinical features of chromoblastomycosis. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - March 29, 2016 Category: Infectious Diseases Authors: L.G. Jessani, M. Thirunarayan, A. Chakrabarti, D. Sureshkumar, A. Parameswaran, R. Gopalakrishnan Tags: Type: Poster Presentation Source Type: research
Chromoblastomycosis.
Authors: Krzyściak PM, Pindycka-Piaszczyńska M, Piaszczyński M
Abstract
Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissue. The infection usually results from a traumatic injury and inoculation of microorganism from a specific group of dematiaceous fungi (usually Fonsecaea pedrosoi, Phialophora verrucosa, Cladophialophora carrionii). In the tissues fungi produce characteristic sclerotic cells or muriform cells. Dermal lesions can range from small nodules to large papillary-like eruptions. The disease has been described worldwide but the prevalence is higher in rural po...
Source: Advances in Dermatology and Allergology - December 11, 2015 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Chromoblastomycosis caused by Cladophialophora carrionii in a skin graft recipient
Publication date: Available online 17 October 2015 Source:Medical Journal Armed Forces India Author(s): Partha Roy, S. Prasanna, Dudhat Vaibhav Laxmikant, C.N. Chaudhari (Source: Medical Journal Armed Forces India)
Source: Medical Journal Armed Forces India - November 7, 2015 Category: Journals (General) Source Type: research
Global Spread of Human Chromoblastomycosis Is Driven by Recombinant Cladophialophora carrionii and Predominantly Clonal Fonsecaea Species
by Shuwen Deng, Clement K. M. Tsui, A. H. G. Gerrits van den Ende, Liyue Yang, Mohammad Javad Najafzadeh, Hamid Badali, Ruoyu Li, Ferry Hagen, Jacques F. Meis, Jiufeng Sun, Somayeh Dolatabadi, Bernard Papierok, Weihua Pan, G. S. de Hoog, Wanqing Liao
Global distribution patterns of Cladophialophora carrionii, agent of human chromoblastomycosis in arid climates of Africa, Asia, Australia, Central-and South-America, were compared with similar data of the vicarious Fonsecaea spp., agents of the disease in tropical rain forests. Population diversities among 73 C. carrionii strains and 60 strains of three Fonsecaea species wer...
Source: PLoS Neglected Tropical Diseases - October 23, 2015 Category: Tropical Medicine Authors: Shuwen Deng et al. Source Type: research
Posaconazole: Use in the Prophylaxis and Treatment of Fungal Infections
Semin Respir Crit Care Med 2015; 36: 767-785DOI: 10.1055/s-0035-1562902Posaconazole, a fluorinated triazole antifungal drug, is approved by the U.S. Food and Drug Administration (FDA) for (1) prophylaxis against Aspergillus and Candida infections in immunocompromised patients at high risk for these infections and (2) oropharyngeal candidiasis (OPC), including cases refractory to fluconazole and/or itraconazole. The European Medicines Agency (EMA) has approved posaconazole for (1) treatment of aspergillosis, fusariosis, chromoblastomycosis, and coccidioidomycosis in patients who are refractory to or intolerant of other azol...
Source: Seminars in Respiratory and Critical Care Medicine - September 23, 2015 Category: Respiratory Medicine Authors: Clark, Nina M.Grim, Shellee A.Lynch, Joseph P. Source Type: research
First case of chromoblastomycosis from Bangladesh
Publication date: Available online 2 September 2015 Source:Medical Mycology Case Reports Author(s): Sophie Brun, Coralie Zumelzu, Mai Ba Hoanganh, Annie Levy, Dea Garcia-Hermoso, Liliane Laroche, Arezki Izri Chromoblastomycosis is a rare and chronic cutaneous and subcutaneous infection caused by black fungi and mostly reported in tropical and subtropical areas. Here we report the first case of chromoblastomycosis from Bangladesh. Molecular biology permitted to identify Fonsecaea nubica, and the patient responded well to antifungal treatment alone. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 4, 2015 Category: Biology Source Type: research
Chromoblastomycosis: a neglected tropical disease.
CHROMOBLASTOMYCOSIS: A NEGLECTED TROPICAL DISEASE.
Rev Inst Med Trop Sao Paulo. 2015 Sep;57 Suppl 19:46-50
Authors: Queiroz-Telles F
Abstract
SUMMARYChromoblastomycosis (CMB) is a chronic fungal infection of the skin and the subcutaneous tissue caused by a transcutaneous traumatic inoculation of a specific group of dematiaceous fungi occurring mainly in tropical and subtropical zones worldwide. If not diagnosed at early stages, patients with CBM require long term therapy with systemic antifungals, sometimes associated with physical methods. Unlike other neglected endemic mycoses, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 1, 2015 Category: Tropical Medicine Authors: Queiroz-Telles F Tags: Rev Inst Med Trop Sao Paulo Source Type: research
