Molecular identification and antifungal susceptibility profiles of clinical strains of < i > Fonsecaea < /i > spp. isolated from patients with chromoblastomycosis in Rio de Janeiro, Brazil
Conclusions/SignificanceF.monophora, the second most frequentFonsecaea species in South America, predominated in patients raised and born in Rio de Janeiro, Brazil, without cerebral involvement in these cases. TRB, VRC, and the AMB/5FC combination should be further investigated as a treatment option for CBM. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - July 26, 2018 Category: Tropical Medicine Authors: Rowena Alves Coelho Source Type: research
Differential distribution patterns of Fonsecaea agents of chromoblastomycosis, exemplified by the first case due to F. monophora from Argentina
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Marcelo Label, Luciana C. Karayan, Sybren De Hoog, Javier Afeltra, Togo Bustamante, Roxana G. VitaleAbstractChromoblastomycosis is a mutilating infection of the skin and subcutaneous tissues caused by melanized fungi belonging to the order Chaetothyriales. Proven cases of the main agent, Fonsecaea pedrosoi are mainly limited to (sub)tropical, humid climates of Latin and Central America and the Caribbean. Fonsecaea monophora has a global distribution along the equator. Cases outside the (sub)tropics have thus far mostly been considered to ...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Mechanisms of copper and zinc homeostasis in pathogenic black fungi
Publication date: June 2018Source: Fungal Biology, Volume 122, Issue 6Author(s): Mirelle Garcia Silva-Bailão, Kassyo Lobato Potenciano da Silva, Laura Raniere Borges dos Anjos, Patrícia de Sousa Lima, Marcus de Melo Teixeira, Célia Maria de Almeida Soares, Alexandre Melo BailãoAbstractBlack fungi comprise a diverse group of melanized microorganisms, many of which are able to infect humans. One of the recognized diseases that arise with black fungi infection is chromoblastomycosis, a neglected implantation mycosis. Considering their ecology, black fungi may face conditions with distinct metal availability. Zinc and copp...
Source: Fungal Biology - July 11, 2018 Category: Biology Source Type: research
Differential distribution patterns of Fonsecaea agents of chromoblastomycosis, exemplified by the first case due to F. monophora from Argentina
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Marcelo Label, Luciana C. Karayan, Sybren De Hoog, Javier Afeltra, Togo Bustamante, Roxana G. VitaleAbstractChromoblastomycosis is a mutilating infection of the skin and subcutaneous tissues caused by melanized fungi belonging to the order Chaetothyriales. Proven cases of the main agent, Fonsecaea pedrosoi are mainly limited to (sub)tropical, humid climates of Latin and Central America and the Caribbean. Fonsecaea monophora has a global distribution along the equator. Cases outside the (sub)tropics have thus far mostly been considered to ...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research
Mechanisms of copper and zinc homeostasis in pathogenic black fungi
Publication date: June 2018Source: Fungal Biology, Volume 122, Issue 6Author(s): Mirelle Garcia Silva-Bailão, Kassyo Lobato Potenciano da Silva, Laura Raniere Borges dos Anjos, Patrícia de Sousa Lima, Marcus de Melo Teixeira, Célia Maria de Almeida Soares, Alexandre Melo BailãoAbstractBlack fungi comprise a diverse group of melanized microorganisms, many of which are able to infect humans. One of the recognized diseases that arise with black fungi infection is chromoblastomycosis, a neglected implantation mycosis. Considering their ecology, black fungi may face conditions with distinct metal availability. Zinc and copp...
Source: Fungal Biology - July 5, 2018 Category: Biology Source Type: research
Melanin particles isolated from the fungus Fonsecaea pedrosoi activates the human complement system.
CONCLUSION: Fonsecaea pedrosoi melanin particles and fungal cell ghosts activated the complement system mainly through an alternative pathway.
PMID: 29947713 [PubMed - in process] (Source: Memorias do Instituto Oswaldo Cruz)
Source: Memorias do Instituto Oswaldo Cruz - June 25, 2018 Category: Infectious Diseases Authors: Pinto L, Granja LFZ, Almeida MA, Alviano DS, Silva MHD, Ejzemberg R, Rozental S, Alviano CS Tags: Mem Inst Oswaldo Cruz Source Type: research
Chromoblastomycosis due to Cladosporium langeronii. Molecular diagnosis of an agent previously diagnosed as Fonsecaea pedrosoi
The objective of this study was to evaluate the susceptibility of emerging fungi to fluconazole, itraconazole and amphotericin B by disk diffusion method. In 2015, 82 emerging fungi were evaluated in IPB-LACEN/RS and 13 (15.8%) were resistant: 10/52 were from superficial mycoses and 3/30 from systemic mycoses. The data from the study point to the need for permanent vigilance regarding the careful evaluation in the prescription and clinical and laboratory follow-up of patients affected by fungal infections. (Source: Anais Brasileiros de Dermatologia)
Source: Anais Brasileiros de Dermatologia - June 18, 2018 Category: Dermatology Source Type: research
First case of chronic cutaneous chromoblastomycosis by Rhinocladiella similis aquired in Europe
Clinical and Experimental Dermatology, EarlyView. (Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - June 9, 2018 Category: Dermatology Authors: N. A. Richarz
,
A. Jaka
,
G. Fern ández‐Rivas
,
J. Bassas
,
I. Bielsa
,
C. Ferrándiz Source Type: research
Case Report: Successful Treatment of Chromoblastomycosis Caused by Fonsecaea monophora in a Patient with Psoriasis Using Itraconazole and Acitretin.
Abstract
Chromoblastomycosis is a worldwide chronic subcutaneous infection caused by dematiaceous fungi and clinically characterized by verrucous lesions. Herein, we report a rare case of chromoblastomycosis caused by Fonsecaea monophora in a 60-year-old male carpenter with a 40-year history of psoriasis from Shandong in northern China. A fungal infection coexisting with psoriasis presents a management dilemma. Our patient responded well to combined itraconazole and acitretin therapy and the lesions resolved completely after 1 month of treatment.
PMID: 29785921 [PubMed - as supplied by publisher] (...
Source: The American Journal of Tropical Medicine and Hygiene - May 21, 2018 Category: Tropical Medicine Authors: Bao F, Wang Q, Yu C, Shang P, Sun L, Zhou G, Wu M, Zhang F Tags: Am J Trop Med Hyg Source Type: research
[Extensive cutaneous chromomycosis: Efficacy of combined terbinafine and cryotherapy].
CONCLUSION: This combined treatment would constitute an excellent therapeutic alternative because of its efficiency, feasibility, low cost, method of administration and aesthetic result.
PMID: 29779858 [PubMed - as supplied by publisher] (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - May 17, 2018 Category: Dermatology Authors: Elkhachine Y, Elbenaye J, Er-Rami M, Sakkah A, Jakar A, Elhaouri M Tags: Ann Dermatol Venereol Source Type: research
From phaeohyphomycosis to disseminated chromoblastomycosis: A retrospective study of infections caused by dematiaceous fungi.
CONCLUSION: Infections caused by dematiaceous fungi are rare. Medullary and brain localizations are extremely rare, especially for chromoblastomycosis. Cutaneous manifestations of phaeohyphomycosis are varied; diagnosis is thus more difficult. It is therefore important, when confronted with a chronic tumor-like lesion in endemic areas, to perform a biopsy for pathology and fungal culture. While surgical excision is not always sufficient, medical treatment of these infections is not standardized, but relies on an azole, which can be associated with another antifungal agent.
PMID: 29656841 [PubMed - as supplied by pu...
Source: Medecine et Maladies Infectieuses - April 17, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Cutaneous chromomycosis caused by Arthrinium arundinis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView. (Source: JDDG)
Source: JDDG - April 17, 2018 Category: Dermatology Authors: SalimGreven
,
FriederikeEgberts
,
MatthiasBuchner
,
VeraBeck ‐Jendroschek
,
KarenVoss
,
JochenBrasch Source Type: research
Endobronchial Topical Amphotericin B Instillation for Pulmonary Chromomycosis After Lung Transplantation: A Case Report
We report a very rare case of pulmonary chromomycosis caused by Scedosporium prolificans that developed after lung transplantation and was successfully treated with endobronchial topical amphotericin B instillation. The subject was a woman in her 50s with a history of bilateral lobar lung transplantation from living donors for idiopathic pulmonary hypertension. Eight years after the lung transplantation, chest radiography X-ray and computed tomography showed an abnormal shadow in the right lung. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - April 1, 2018 Category: Transplant Surgery Authors: H. Mitomo, A. Sakurada, Y. Matsuda, H. Notsuda, T. Watanabe, H. Oishi, H. Niikawa, S. Maeda, M. Noda, T. Sado, T. Amemiya, Y. Yoshida, T. Kikuchi, K. Kamei, Y. Okada Tags: Original Contributions: Case Reports Source Type: research
Combination of amphotericin B and terbinafine against melanized fungi associated with chromoblastomycosis.
Abstract
Our in vitro studies showed that combination of amphotericin B and terbinafine had synergistic effects against the majority of melanized fungi associated with chromoblastomycosis (CBM) and similar infections, including Cladophialophora carrionii, C. arxii, Exophiala dermatitidis, E. spinifera, Fonsecaea monophora, F. nubica, F. pedrosoi, and Phialophora verrucosa. This combination could provide an option for treatment of severe or unresponsive cases of CBM, particularly in cases due to species of Fonsecaea and Cladophialophora.
PMID: 29581111 [PubMed - as supplied by publisher] (Source: An...
Source: Antimicrobial Agents and Chemotherapy - March 26, 2018 Category: Microbiology Authors: Deng S, Lei W, de Hoog GS, Yang L, Vitale RG, Rafati H, Seyedmousavi M, Tolooe A, van der Lee H, Liao W, Verweij PE, Seyedmousavi S Tags: Antimicrob Agents Chemother Source Type: research
