Residual gallbladder stones after cholecystectomy: A literature review
Conclusion: Residual gallbladder stones following incomplete gallbladder removal is an important sequelae after cholecystectomy. Completion cholecystectomy (open or laparoscopic) is the most common treatment modality reported in the literature for the management of residual gallbladder stones. (Source: Journal of Minimal Access Surgery)
Source: Journal of Minimal Access Surgery - October 1, 2015 Category: Surgery Authors: Pradeep ChowbeyAnil SharmaAmit GoswamiYusuf AfaqueKhoobsurat NajmaManish BaijalVandana SoniRajesh Khullar Source Type: research

Rhesus rotavirus VP4 sequence-specific activation of mononuclear cells is associated with cholangiopathy in murine biliary atresia
In this study, we investigated how VP4 governs induction of murine BA. Newborn mice were injected with 16 strains of rotavirus and observed for clinical symptoms of BA and mortality. Cholangiograms were performed to confirm bile duct obstruction. Livers and bile ducts were harvested 7 days postinfection for virus titers and histology. Flow cytometry assessed mononuclear cell activation in harvested cell populations from the liver. Cytotoxic NK cell activity was determined by the ability of NK cells to kill noninfected cholangiocytes. Of the 16 strains investigated, the 6 with the highest homology to the RRV VP4 (>87%) w...
Source: AJP: Gastrointestinal and Liver Physiology - September 15, 2015 Category: Gastroenterology Authors: Walther, A., Mohanty, S. K., Donnelly, B., Coots, A., Lages, C. S., Lobeck, I., Dupree, P., Meller, J., McNeal, M., Sestak, K., Tiao, G. Tags: LIVER AND BILIARY TRACT PHYSIOLOGY/PATHOPHYSIOLOGY Source Type: research

Increasing the Safety of Cholecystectomy in the Rural Setting with Mandatory Intraoperative Cholangiogram
Common bile duct injury (CBD) is a catastrophic complication of cholecystectomy. There is literature that supports the use of an intraoperative cholangiogram (IOC) to decrease the incidence of CBD injury. From 2011-2013, there were 3 CBD injuries at our rural institution. Because both permanent and locum tenems perform surgery at our hospital, we implemented an IOC policy in hopes of decreasing our incidence of CBD injuries. (Source: Journal of the American College of Surgeons)
Source: Journal of the American College of Surgeons - September 14, 2015 Category: Surgery Authors: Melany C. Hughes, Gregory T. Jarrin, Brian A. Bucina Tags: General Surgery/Acute Care Surgery and Miscellaneous Source Type: research

Transgastric biliary brushing: a novel endoscopic technique
A 71-year-old woman with pancreatic adenocarcinoma status post-Whipple presented with obstructive jaundice due to suspected tumor recurrence. Single-balloon enteroscopy was unable to reach the hepaticojejunostomy. EUS with FNA was not feasible due to altered anatomy. The echoendoscope was advanced into the stomach, and the left intrahepatic duct was accessed. A cholangiogram revealed biliary dilation proximal to an anastomotic stricture. A guidewire was advanced into the left biliary system, but could not be advanced across the anastomosis into the jejunum. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 28, 2015 Category: Gastroenterology Authors: Yamel Flores Carmona, Amy Tyberg, Steven Zerbo, Reem Sharaiha, Michel Kahaleh Tags: VideoGIE Source Type: research

Endoscopic closure of iatrogenic duodenal perforation using dual over-the-scope clips
A 44-year-old woman was referred for ERCP after an intraoperative cholangiogram done during laparoscopic cholecystectomy showed common bile duct stones. A 1.5-cm full-thickness perforation was found in the anterior wall of the second portion of the duodenum immediately after insertion of the duodenoscope (Fig. 1). An over-the-scope clip (OTSC) 12/6 type gc was attached to the upper endoscope, and a twin grasper was used to grasp the edges of the perforation (Video 1, available online at www.giejournal.org). (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - August 15, 2015 Category: Gastroenterology Authors: Tejas Kirtane, Shashideep Singhal Tags: VideoGIE Source Type: research