Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Perinatal Mental Health Support for Parents of Color: Interview with Lauren Elliott, Founder of Candlelit Therapy
Perinatal mood and anxiety disorders are very common, and can cause significant suffering and distress for many new parents. Black women and women of color are often at higher risk of such disorders. Despite this, there has been a lack of culturally relevant mental health supports for such parents. Candlelit Therapy, a company based in New York City, aims to change this by providing access to mental health supports that are specifically designed for new or expecting parents who are black, indigenous, and people of color (BIPOC). The services provided by Candlelit Therapy include Candlelit Care, a point-of-care digital t...
Source: Medgadget - April 29, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Ob/Gyn Pediatrics Reproductive Medicine Society Source Type: blogs

45 Never Force Anyone to Talk To You Quotes
You can’t really force someone to do something. Sure, you may wish that you could sometimes. But trying to do that only tends to drive them away and push you further from what you want. So in this post I’d like to reinforce that and mention more helpful and healthy alternatives by sharing the best 45 never force anyone to talk to you quotes. I hope this post will help you see how futile it is to try to force something and what you can do instead. And, perhaps even more importantly, what you can do when someone else is trying to force something – words, actions, thoughts – upon you. And if you want even mor...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - April 28, 2022 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs

Collaborative neuroimaging initiative BrainChart helps chart how brains change across the lifespan
This article was originally published on The Conversation. The post Collaborative neuroimaging initiative BrainChart helps chart how brains change across the lifespan appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - April 26, 2022 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Technology & Innovation ageing brain changes brain charts brain scans brain-development computerised tomography lifespan magnetic resonance imaging mental illness neuroimaging Source Type: blogs

Empowering Trainees to be Leaders and Change Agents
We described several wellness initiatives that were done at individual campuses. The University of Illinois where I attend, we had a wellness committee that we formed led by students. We were able to partner with local companies to bring in more healthy food options. We were able to set up a counseling center dedicated specifically towards medical trainees. Joe Geraghty: And so that’s at the institutional level, but then in our local community, we had several letters from places like the University of Chicago. We had a medical student who wrote about how they were developing kind of like easy to digest infograp...
Source: Academic Medicine Blog - April 25, 2022 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Annual Call for Trainee-Authored Letters to the Editor ATLAS Trainee Perspective leadership medical education scholarship medical students residents scholarly publishing trainee engagement Source Type: blogs