Use of Rectus Flaps in Reconstructive Surgery for Gynecologic Cancer
In conclusion, pelvic reconstruction with RAM/RAMP flaps, at the time of radical surgery for gynecologic cancer, is an uncommon procedure. In our case series, we had a significant complication rate with the most common being infection and necrosis. The development of a team approach, with input from services including Gynecologic Oncology and Plastic Surgery should be developed to decrease post-operative complications and improve patient outcomes.PMID:38248111 | PMC:PMC10814897 | DOI:10.3390/curroncol31010026 (Source: Current Oncology)
Source: Current Oncology - January 22, 2024 Category: Cancer & Oncology Authors: Oleksandra Dzyubak Lina Salman Allan Covens Source Type: research
Giant Ulcer with Necrosis on Right Vulva, Groin, and Thigh-- A Case of Necrotizing Fasciitis Associated with Erythematous Pemphigus
We report a case of a 72-year female with erythematous pemphigus who developed erythema, swelling and ulceration on right vulva, groin, and thigh. The early clinical manifestations of the patient were nonspecific and easily misdiagnosed as cellulitis. However, upon the occurrence of ulceration and necrosis, deep fungal infection, pyoderma gangrenosum or lymphoproliferative disorders were considered. The pathology suggested IgG4-related diseases, plasmacytoma et al. But at last, surgical exploration and postoperative pathology confirmed the diagnosis of necrotizing fasciitis. The patient recovered after multiple aggressive ...
Source: Clinical, Cosmetic and Investigational Dermatology - January 18, 2024 Category: Dermatology Authors: Miao Wan Xiangrong Xu Xiaojiao Zhao Xia You Guiying Zhang Hai Long Ping He Jian Long Jianjian Zhu Source Type: research
A Novel Integrated Clinical –Biochemical–Radiological and Sonographic Classification of Necrotizing Enterocolitis
Conclusion In this cohort, a combination of specific IUS markers and clinical signs of instability, abdominal wall cellulitis, plus laboratory markers were diagnostic of NEC requiring interventions.
Key Points
[...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - January 11, 2024 Category: Perinatology & Neonatology Authors: Elsayed, Yasser Louis, Deepak Hinton, Martha Seshia, Mary Alvaro, Ruben Dakshinamurti, Shyamala Tags: Original Article Source Type: research
Management of breast cancer —related lymphedema using free medial sural artery perforator (MSAP) flap: a VLVT approach
We describe the use of the free medial sural artery perforator (MSAP) flap in the management of breast cancer-related lymphedema (BCRL). Patients with BCRL undergoing free MSAP flaps from 2020 to 2021 were identified. Patient characteristics, postoperative outcome, and quality of life were evaluated. Three patients underwent free MSAP flap. Average age and BMI were 41 years and 32.5 kg/m2, respectively. The three flaps survived completely. No donor site lymphedema was observed. No cellulitis infections developed. The three patients had a noticeable improvement in the diameter of the limb and reported a high satisfactio...
Source: European Journal of Plastic Surgery - January 10, 2024 Category: Cosmetic Surgery Source Type: research
Haemolysin Ahh1 secreted from Aeromonas dhakensis activates the NLRP3 inflammasome in macrophages and mediates severe soft tissue infection
Int Immunopharmacol. 2024 Jan 4;128:111478. doi: 10.1016/j.intimp.2023.111478. Online ahead of print.ABSTRACTSevere soft tissue infections caused by Aeromonas dhakensis, such as necrotizing fasciitis or cellulitis, are prevalent in southern Taiwan and around the world. However, the mechanism by which A. dhakensis causes tissue damage remains unclear. Here, we found that the haemolysin Ahh1, which is the major virulence factor of A. dhakensis, causes cellular damage and activates the NLR family pyrin domain containing 3 (NLRP3) inflammasome signalling pathway. Deletion of ahh1 significantly downregulated caspase-1, the proi...
Source: International Immunopharmacology - January 6, 2024 Category: Allergy & Immunology Authors: Yu-Cheng Su Ching-Chun Wang Yi-Wei Chen Sin-Tian Wang Cing-Ying Shu Pei-Jane Tsai Wen-Chien Ko Chang-Shi Chen Po-Lin Chen Source Type: research
Haemolysin Ahh1 secreted from Aeromonas dhakensis activates the NLRP3 inflammasome in macrophages and mediates severe soft tissue infection
Int Immunopharmacol. 2024 Jan 4;128:111478. doi: 10.1016/j.intimp.2023.111478. Online ahead of print.ABSTRACTSevere soft tissue infections caused by Aeromonas dhakensis, such as necrotizing fasciitis or cellulitis, are prevalent in southern Taiwan and around the world. However, the mechanism by which A. dhakensis causes tissue damage remains unclear. Here, we found that the haemolysin Ahh1, which is the major virulence factor of A. dhakensis, causes cellular damage and activates the NLR family pyrin domain containing 3 (NLRP3) inflammasome signalling pathway. Deletion of ahh1 significantly downregulated caspase-1, the proi...
Source: International Immunopharmacology - January 6, 2024 Category: Allergy & Immunology Authors: Yu-Cheng Su Ching-Chun Wang Yi-Wei Chen Sin-Tian Wang Cing-Ying Shu Pei-Jane Tsai Wen-Chien Ko Chang-Shi Chen Po-Lin Chen Source Type: research
Pediatric preseptal and orbital cellulitis - a 6 year experience from a London tertiary centre
CONCLUSIONS: We recommend all patients with superior SPA be treated at a centre with both ENT and orbital surgeons as these may not be amenable to drainage by ENT alone.PMID:38165256 | DOI:10.1080/01676830.2023.2296563 (Source: Orbit)
Source: Orbit - January 2, 2024 Category: Opthalmology Authors: Allan Z Nghiem Blanca Sanz-Magallon Reem Farwana Sarah F Osborne Source Type: research
Pediatric preseptal and orbital cellulitis - a 6 year experience from a London tertiary centre
CONCLUSIONS: We recommend all patients with superior SPA be treated at a centre with both ENT and orbital surgeons as these may not be amenable to drainage by ENT alone.PMID:38165256 | DOI:10.1080/01676830.2023.2296563 (Source: Orbit)
Source: Orbit - January 2, 2024 Category: Opthalmology Authors: Allan Z Nghiem Blanca Sanz-Magallon Reem Farwana Sarah F Osborne Source Type: research
