Exposure to psychotropic drugs and breast cancer risk in patients with bipolar disorder and major depressive disorder: a nested case-control study
This study aimed to assess such risk among women with major depressive disorder (MDD) and bipolar disorder (BD). A nested case-control study design was used with data obtained from the Taiwan National Health Insurance Research Database. Logistic regression analysis with adjustments for demographic characteristics, medical and mental comorbidities, and all-cause clinical visits was performed to estimate the risk of breast cancer according to the cumulative defined daily dose (cDDD) of psychotropic drugs. The study included 1564 women with MDD or BD who had breast cancer, and 15,540 women with MDD or BD who did not have brea...
Source: Clinical Breast Cancer - March 30, 2024 Category: Cancer & Oncology Authors: Dian-Jeng Li Shih-Jen Tsai Tzeng-Ji Chen Chih-Sung Liang Mu-Hong Chen Source Type: research
Exposure to psychotropic drugs and breast cancer risk in patients with bipolar disorder and major depressive disorder: a nested case-control study
This study aimed to assess such risk among women with major depressive disorder (MDD) and bipolar disorder (BD). A nested case-control study design was used with data obtained from the Taiwan National Health Insurance Research Database. Logistic regression analysis with adjustments for demographic characteristics, medical and mental comorbidities, and all-cause clinical visits was performed to estimate the risk of breast cancer according to the cumulative defined daily dose (cDDD) of psychotropic drugs. The study included 1564 women with MDD or BD who had breast cancer, and 15,540 women with MDD or BD who did not have brea...
Source: Clinical Genitourinary Cancer - March 30, 2024 Category: Cancer & Oncology Authors: Dian-Jeng Li Shih-Jen Tsai Tzeng-Ji Chen Chih-Sung Liang Mu-Hong Chen Source Type: research
Exposure to psychotropic drugs and breast cancer risk in patients with bipolar disorder and major depressive disorder: a nested case-control study
This study aimed to assess such risk among women with major depressive disorder (MDD) and bipolar disorder (BD). A nested case-control study design was used with data obtained from the Taiwan National Health Insurance Research Database. Logistic regression analysis with adjustments for demographic characteristics, medical and mental comorbidities, and all-cause clinical visits was performed to estimate the risk of breast cancer according to the cumulative defined daily dose (cDDD) of psychotropic drugs. The study included 1564 women with MDD or BD who had breast cancer, and 15,540 women with MDD or BD who did not have brea...
Source: Cancer Control - March 30, 2024 Category: Cancer & Oncology Authors: Dian-Jeng Li Shih-Jen Tsai Tzeng-Ji Chen Chih-Sung Liang Mu-Hong Chen Source Type: research
Exposure to psychotropic drugs and breast cancer risk in patients with bipolar disorder and major depressive disorder: a nested case-control study
This study aimed to assess such risk among women with major depressive disorder (MDD) and bipolar disorder (BD). A nested case-control study design was used with data obtained from the Taiwan National Health Insurance Research Database. Logistic regression analysis with adjustments for demographic characteristics, medical and mental comorbidities, and all-cause clinical visits was performed to estimate the risk of breast cancer according to the cumulative defined daily dose (cDDD) of psychotropic drugs. The study included 1564 women with MDD or BD who had breast cancer, and 15,540 women with MDD or BD who did not have brea...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 30, 2024 Category: Psychiatry Authors: Dian-Jeng Li Shih-Jen Tsai Tzeng-Ji Chen Chih-Sung Liang Mu-Hong Chen Source Type: research
Exposure to psychotropic drugs and breast cancer risk in patients with bipolar disorder and major depressive disorder: a nested case-control study
This study aimed to assess such risk among women with major depressive disorder (MDD) and bipolar disorder (BD). A nested case-control study design was used with data obtained from the Taiwan National Health Insurance Research Database. Logistic regression analysis with adjustments for demographic characteristics, medical and mental comorbidities, and all-cause clinical visits was performed to estimate the risk of breast cancer according to the cumulative defined daily dose (cDDD) of psychotropic drugs. The study included 1564 women with MDD or BD who had breast cancer, and 15,540 women with MDD or BD who did not have brea...
Source: Clinical Genitourinary Cancer - March 30, 2024 Category: Cancer & Oncology Authors: Dian-Jeng Li Shih-Jen Tsai Tzeng-Ji Chen Chih-Sung Liang Mu-Hong Chen Source Type: research
Exposure to psychotropic drugs and breast cancer risk in patients with bipolar disorder and major depressive disorder: a nested case-control study
This study aimed to assess such risk among women with major depressive disorder (MDD) and bipolar disorder (BD). A nested case-control study design was used with data obtained from the Taiwan National Health Insurance Research Database. Logistic regression analysis with adjustments for demographic characteristics, medical and mental comorbidities, and all-cause clinical visits was performed to estimate the risk of breast cancer according to the cumulative defined daily dose (cDDD) of psychotropic drugs. The study included 1564 women with MDD or BD who had breast cancer, and 15,540 women with MDD or BD who did not have brea...
Source: Clinical Breast Cancer - March 30, 2024 Category: Cancer & Oncology Authors: Dian-Jeng Li Shih-Jen Tsai Tzeng-Ji Chen Chih-Sung Liang Mu-Hong Chen Source Type: research
Exposure to psychotropic drugs and breast cancer risk in patients with bipolar disorder and major depressive disorder: a nested case –control study
This study aimed to assess such risk among women with major depressive disorder (MDD) and bipolar disorder (BD). A nested case –control study design was used with data obtained from the Taiwan National Health Insurance Research Database. Logistic regression analysis with adjustments for demographic characteristics, medical and mental comorbidities, and all-cause clinical visits was performed to estimate the risk of breast cancer according to the cumulative defined daily dose (cDDD) of psychotropic drugs. The study included 1564 women with MDD or BD who had breast cancer, and 15,540 women with MDD or BD who did not have b...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 30, 2024 Category: Neuroscience Source Type: research
Combining SSRIs With Oral Anticoagulants Found to Increase Risk of Major Bleeding
People who take serotonin reuptake inhibitors (SSRIs) and oral anticoagulants have an increased risk of multiple types of major bleeding compared with people who take only oral anticoagulants, astudy inJAMA Network Open has found. The study findings also showed that bleeding risk differs depending on the type of anticoagulant.Christel Renoux, M.D., Ph.D., of Jewish General Hospital in Montreal and colleagues examined data from 331,305 patients in the United Kingdom aged 60 years or older who had atrial fibrillation and began taking oral anticoagulants between January 2, 1998, and March 29, 2021. The researchers included an...
Source: Psychiatr News - March 26, 2024 Category: Psychiatry Tags: adverse event anticoagulant bleeding blood thinner JAMA Network Open risk factor selective serotonin reuptake inhibitor SSRI warfarin Source Type: research
Current Understanding of Compulsive Sexual Behavior Disorder and Co-occurring Conditions: What Clinicians Should Know about Pharmacological Options
AbstractCompulsive sexual behavior disorder (CSBD) has recently been recognized as a psychiatric disorder. Pharmacological treatments for CSBD have received little study and thus have limited empirical support. The main objective of the present work is to review existing literature on the efficacy of different drugs on the symptomatology of CSBD, including the subtype of problematic pornography use (PPU). The main pharmacological approaches to treating CSBD have included opioid antagonists (naltrexone and nalmefene), selective serotonin reuptake inhibitors (paroxetine, citalopram, fluoxetine, and sertraline), mood stabiliz...
Source: CNS Drugs - March 14, 2024 Category: Neurology Source Type: research
Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi-computational investigation
Comput Biol Chem. 2024 Feb 29;110:108039. doi: 10.1016/j.compbiolchem.2024.108039. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) persists to be one of the most devastating and deadliest malignancies globally. Recent research into the molecular signaling networks entailed in many malignancies has given some prominent insights that can be leveraged to create molecular therapeutics for combating HCC. Therefore, in the current communication, an in-silico drug repurposing approach has been employed to target the function of PTP4A3/PRL-3 protein in HCC using antidepressants: Fluoxetine hydrochloride, Citalopram, A...
Source: Computational Biology and Chemistry - March 12, 2024 Category: Bioinformatics Authors: Ishfaq Hassan Mir Kankipati Teja Shyam Susmida Seni Balakrishnan Muthuvel Suresh Kumar Thiyagarajan Ramesh Chinnasamy Thirunavukkarasu Source Type: research
Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi-computational investigation
Comput Biol Chem. 2024 Feb 29;110:108039. doi: 10.1016/j.compbiolchem.2024.108039. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) persists to be one of the most devastating and deadliest malignancies globally. Recent research into the molecular signaling networks entailed in many malignancies has given some prominent insights that can be leveraged to create molecular therapeutics for combating HCC. Therefore, in the current communication, an in-silico drug repurposing approach has been employed to target the function of PTP4A3/PRL-3 protein in HCC using antidepressants: Fluoxetine hydrochloride, Citalopram, A...
Source: Computational Biology and Chemistry - March 12, 2024 Category: Bioinformatics Authors: Ishfaq Hassan Mir Kankipati Teja Shyam Susmida Seni Balakrishnan Muthuvel Suresh Kumar Thiyagarajan Ramesh Chinnasamy Thirunavukkarasu Source Type: research
Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi-computational investigation
Comput Biol Chem. 2024 Feb 29;110:108039. doi: 10.1016/j.compbiolchem.2024.108039. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) persists to be one of the most devastating and deadliest malignancies globally. Recent research into the molecular signaling networks entailed in many malignancies has given some prominent insights that can be leveraged to create molecular therapeutics for combating HCC. Therefore, in the current communication, an in-silico drug repurposing approach has been employed to target the function of PTP4A3/PRL-3 protein in HCC using antidepressants: Fluoxetine hydrochloride, Citalopram, A...
Source: Computational Biology and Chemistry - March 12, 2024 Category: Bioinformatics Authors: Ishfaq Hassan Mir Kankipati Teja Shyam Susmida Seni Balakrishnan Muthuvel Suresh Kumar Thiyagarajan Ramesh Chinnasamy Thirunavukkarasu Source Type: research
Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting
CONCLUSION: New associations between commonly prescribed antepartum medications and orofacial clefting were found. These findings should be confirmed as causality is not assessed in this report. Practitioners should be aware of the potential increased risk associated with these medications.PMID:38449319 | DOI:10.1177/10556656241237679 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - March 7, 2024 Category: ENT & OMF Authors: Matteo Laspro Hilliard T Brydges Alexandra N Verzella Jill Schechter Andre Alcon Ashley S Roman Roberto L Flores Source Type: research
Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting
CONCLUSION: New associations between commonly prescribed antepartum medications and orofacial clefting were found. These findings should be confirmed as causality is not assessed in this report. Practitioners should be aware of the potential increased risk associated with these medications.PMID:38449319 | DOI:10.1177/10556656241237679 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - March 7, 2024 Category: ENT & OMF Authors: Matteo Laspro Hilliard T Brydges Alexandra N Verzella Jill Schechter Andre Alcon Ashley S Roman Roberto L Flores Source Type: research
