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citalopram, Celexa
Title: citalopram, CelexaCategory: MedicationsCreated: 2/2/1999 12:00:00 AMLast Editorial Review: 8/29/2017 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - August 29, 2017 Category: Psychiatry Source Type: news

Serotonergic 5HTTLPR/rs25531 s-allele homozygosity associates with violent suicides in male citalopram users - Rahikainen AL, Majaharju S, Haukka J, Palo JU, Sajantila A.
Depressive disorders are involved as a background factor in over 50% of suicide cases. The most widely used antidepressants today are serotonin selective reuptake inhibitors (SSRIs). However, not all users benefit from SSRI medication. Although the overall... (Source: SafetyLit)
Source: SafetyLit - June 15, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

OCD pills could be a weapon in the war on obesity
A series of trials, researchers found that when people took citalopram, prescribed for depression and obsessive compulsive disorder they were more likely to pick healthy food. (Source: the Mail online | Health)
Source: the Mail online | Health - April 1, 2017 Category: Consumer Health News Source Type: news

Not Just for Attention: Stop Teen Suicide
The subject of depression and suicide, especially in the case of children and teens, is a tremendous concern. Unfortunately, many cases go missed not necessarily because those surrounding these young people don’t care or pay enough attention to them, but more because they aren’t aware of what to look out for. I am a suicide survivor. I also grew up with a suicidal mother and witnessed a peer successfully commit suicide, ironically, when I was in the emergency room beside her being treated for the same thing. I was saved, while her family still mourns for her. These experiences, including the fact that my twelve...
Source: Psych Central - March 29, 2017 Category: Psychiatry Authors: Chynna Laird Tags: Antidepressants Children and Teens Depression Medications Personal Stories Self-Esteem Stress Suicide Therapists Spill Treatment Anxiety Coping Skills Depression Mood Depressive Episode Major Depressive Disorder Monoamine Oxi Source Type: news

Single Dose of SSRI Prompted Healthy Food Choices During Test
Citalopram increased choices of more versus fewer healthy foods relative to placebo (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - March 23, 2017 Category: Psychiatry Tags: Neurology, Psychiatry, Journal, Source Type: news

Celexa (Citalopram Hydrobromide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

The 6 Medications You Should Never Take When Driving
It’s a given that safe driving needs concentration, alertness and an ability to react in a coordinated and timely fashion. But what may not occur to you is that the medications you’re taking can seriously impact all of these things. And it’s not just prescription medications, but over-the-counter products as well. “While laws differ from state to state, you can be charged with a DUI if caught driving hazardously while taking prescription or OTC meds, even if your doctor wrote you that prescription,” adds C. Michael White, Pharm.D., FCP, FCCP, Professor and Head of the Department of Pharmacy Pr...
Source: Healthy Living - The Huffington Post - October 4, 2016 Category: Consumer Health News Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl ...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Pharmacogenetics of citalopram-related side effects in children with depression and/or anxiety disorders - Amitai M, Kronenberg S, Carmel M, Michaelovsky E, Frisch A, Brent D, Apter A, Chen A, Weizman A, Fennig S.
Pharmacogenetic approach to antidepressant (AD) response is a promising avenue toward individualizing AD treatment. This is particularly relevant in pediatric populations because of concerns about the suicide risk of serotonin selective reuptake inhibitors... (Source: SafetyLit)
Source: SafetyLit - June 26, 2016 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Unintended Consequences: FDA Drug Safety Warning BackfiresUnintended Consequences: FDA Drug Safety Warning Backfires
FDA warnings to reduce the daily dosage of citalopram to 40 mg or less to avoid the possibility of cardiac arrhythmias not only failed to do so but also resulted in poor mental health outcomes. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - June 13, 2016 Category: Psychiatry Tags: Psychiatry News Source Type: news

Clinical trial examines treatment of complicated grief
A new study reports on the results of a randomized clinical trial that looked at whether the antidepressant citalopram would enhance complicated grief treatment psychotherapy, and if citalopram would be efficacious without it. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 8, 2016 Category: Science Source Type: news

Your NEJM Group Today: CABG Review, Citalopram Dose Reductions, Florida Primary Care/ID Opportunity (FREE)
By the Editors NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today:NEJM Clinical Practice Center: Review article: Coronary-artery … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 22, 2016 Category: Primary Care Source Type: news

Antidepressants and pregnancy: More research needed
Follow me at @Drmoniquetello For many women, pregnancy and the arrival of a new baby is a joyous time — but not for every woman. Recently, postpartum depression — extreme feelings of sadness and anxiety following the birth of a child — has come out from the shadows. But what about depression during pregnancy? It’s more common than you think: as many as 14% to 23% of pregnant women will experience symptoms of depression. It’s of sufficient public health concern that the U.S. Preventive Services Task Force recommends screening all pregnant women and new moms for depression. However, treatin...
Source: New Harvard Health Information - May 19, 2016 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Anxiety and Depression Behavioral Health Drugs and Supplements Family Planning and Pregnancy Source Type: news

SSRI May Help Alzheimer's Agitation, but Caveats AboundSSRI May Help Alzheimer's Agitation, but Caveats Abound
The selective serotonin reuptake inhibitor citalopram may reduce agitation in patients with Alzheimer's disease, but only at high doses, which are not recommended by the FDA. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - April 12, 2016 Category: Psychiatry Tags: Psychiatry News Source Type: news

Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
Researchers have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 6, 2016 Category: Science Source Type: news

Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
(Oregon Health & Science University) Researchers at Oregon Health & Science University's Vollum Institute have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study, published online today in the journal Nature, provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 6, 2016 Category: Biology Source Type: news

FDA Drug Safety Communication: Abnormal heart rhythms associated with high doses of Celexa (citalopram hydrobromide)
[8-24-2011] The U.S. Food and Drug Administration (FDA) is informing healthcare professionals and patients that the antidepressant Celexa (citalopram hydrobromide; also marketed as generics) should no longer be used at doses greater than 40 mg per day because it can cause abnormal changes in the electrical activity of the heart. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 14, 2016 Category: Drugs & Pharmacology Source Type: news

Comunicado de la FDA sobre la seguridad de los medicamentos: Ritmos cardíacos anormales asociados con dosis altas de Celexa (bromhidrato de citalopram)
El 24 de agosto de 2011 la Administración de Alimentos y Medicamentos de los EE. UU. (FDA) informó a los profesionales de la salud y los pacientes que el antidepresivo Celexa (bromhidrato de citalopram, también comercializado como genérico) ya no debe utilizarse en dosis superiores a 40 mg por día ya que puede causar cambios anormales en la actividad eléctrica del corazón. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 29, 2016 Category: Drugs & Pharmacology Source Type: news

What I Learn on the Orange Couch: Creating Boundaries for the First Time
(Stitching by Alisa Burke) His shoes are almost always brown. Sometimes, like last week, his socks match his bright green jacket, which I think is worn on days with rain. But I can't be sure; my evidence is sketchy, inconsistent, and random. I sit across from him, on a nubby burnt orange sofa that feels sturdy and new-ish and is so dark it is almost red; it is long enough for a family of four, depending on the capacity of that family for closeness. Which, perhaps, is the point in his line of work. In May of last year, I started seeing a psychiatrist; it is time for us to shed the stigma that rides alongside mental health ...
Source: Healthy Living - The Huffington Post - February 19, 2016 Category: Consumer Health News Source Type: news

Antidepressants have been a lifesaver for me
Medicated depressives may kill themselves - but the unmedicated ones are far more likely to do so. It's dangerous to just dismiss these drugs (Source: Telegraph Health)
Source: Telegraph Health - January 28, 2016 Category: Consumer Health News Tags: antidepressants depression prescription clinical trials citalopram rates suicide side effects studies overprescription Britain Source Type: news

Comunicado de la FDA sobre la seguridad de los medicamentos: Recomendaciones modificadas para Celexa (citalopram bromhidrato) relacionadas con el riesgo potencial de ritmo cardiaco anormal con dosis altas
El 28 de marzo del 2012, la Administración de Alimentos y Medicamentos de Estados Unidos (FDA por sus siglas en inglés) clarificó recomendaciones sobre dosis y advertencias para el antidepresivo Celexa (citalopram bromhidrato; también disponible como medicamento genérico). (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 19, 2016 Category: Drugs & Pharmacology Source Type: news

Talking therapy 'as effective as antidepressants' study finds
ConclusionPrevious research has shown that both second generation antidepressants and CBT can be helpful for people with depression. This study found that they seem to work about as well as each other.The study has many strengths, including the fact it is a systematic review, and includes information from RCTs involving more than 1,500 people. However, the studies don't give us much information about adverse effects of treatments, or who responds best to which type of treatment. This is important, because what works for one person may not work as well for another. Some doctors think people with severe depression need to be...
Source: NHS News Feed - December 10, 2015 Category: Consumer Health News Tags: Mental health Medical practice Source Type: news

Cortisol supplement combined with psychotherapy and citalopram improves depression outcomes in patients with hypocortisolism after traumatic brain injury - Luo L, Chai Y, Jiang R, Chen X, Yan T.
Depression is one of the most prevalent psychiatric disorders in people with Traumatic brain injury (TBI). Depression after TBI is closely related with social and psychological factors and hypothalamic-pituitary -adrenal (HPA) axis dysfunction. However, th... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - December 4, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Antidepressant paroxetine study 'under-reported data on harms'
ConclusionThis study stands as a warning about how supposedly neutral scientific research papers may mislead readers by presenting findings in a certain way.The differences between the independent analysis published in the BMJ and the 2001 research paper are stark. They cannot both be right. The "authors" of the 2001 paper appear to have picked outcome measures to suit their results, in the way they present evidence of effectiveness. It has subsequently come to light that the first draft paper was not actually written by the 22 academics named on the paper, but by a "ghostwriter" paid by GSK.The st...
Source: NHS News Feed - September 17, 2015 Category: Consumer Health News Tags: Medical practice Medication Mental health Pregnancy/child Source Type: news

Case report: veno-venous ECMO as a bridge to lung transplantation in paraquat poisoning
3 out of 5 stars Successful extracorporeal membrane oxygenation therapy as a bridge to sequential bilateral lung transplantation for a patient after severe paraquat poisoning. Tang X et al.  Clin Toxicol 2015 Aug 28 [Epub ahead of print] Abstract Conceptually, extracorporeal membrane oxygenation (ECMO) seems a perfect technique for treating some of the sickest toxicology patients,  buying time until failing vital functions can recover. With severe cardiotoxins — for example, calcium channel blockers, beta blockers or bupropion — veno-arterial ECMO can provide complete cardiopulmonary bypass, replacin...
Source: The Poison Review - September 9, 2015 Category: Toxicology Authors: Leon Tags: Medical ECMO extracorporeal membrane oxygenation lung transplantation paraquat poisoning Source Type: news

Living with Panic Attacks
You’re sitting in your car trying to will yourself to walk into the grocery store. Anxiety washes over you. You’re cold and hot at the same time with sweat trickling down your back, hair standing on your arms. You finally get out of your car. But as you enter the store, you feel wobbly and like you’re going to pass out. The fluorescent lighting seems especially stifling. The wide aisles, oddly enough, feel claustrophobic. Your breath feels finite, like a balloon floating up to the sky, which you can’t catch. In fact, at times you feel like you’re floating along with the balloon. At times you f...
Source: Psych Central - September 3, 2015 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Anxiety Cognitive-Behavioral Disorders General Psychotherapy Relaxation and Meditation Self-Esteem Self-Help Stress Academy of Cognitive Therapy Agoraphobia Antidepressant Anxiety Disorder Association for Behavioral and Cognitive Source Type: news

Vortioxetine in depression: No hint of added benefit
A review of the drug Vortioxetine has concluded that there is no suitable data for acute treatment or for relapse prevention. The evidence was only partly considered for the indirect comparison with citalopram. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 11, 2015 Category: Science Source Type: news

Seven years on, I still can't get off my antidepressants
Doctors failed to warn Clare Marks of possible withdrawal effects when they prescribed her the drugs (Source: Telegraph Health)
Source: Telegraph Health - August 3, 2015 Category: Consumer Health News Tags: antidepressant depression withdrawal effects health citalopram drugs symptoms Cherrill Hicks adiction doctor Source Type: news

Seven years on, I still can't get off my antidepressants
Doctors failed to warn Clare Marks of possible withdrawal effects when they prescribed her the drugs (Source: The Telegraph : Health Advice)
Source: The Telegraph : Health Advice - August 3, 2015 Category: Consumer Health News Tags: antidepressant depression withdrawal effects health citalopram drugs symptoms Cherrill Hicks adiction doctor Source Type: news

How do common medications influence moral decisions?
A recent study shows that medications used to treat depression and Parkinson’s disease can alter moral decision-making in healthy people. Lead author Molly Crockett discusses what we can and cannot conclude from these findings.Can drugs change our morals? My colleagues and I recently addressed this question in a study carried out at University College London. We gave healthy people the opportunity to earn money by delivering painful electric shocks to either themselves or others, and investigated how common medications influence these moral decisions. One group of volunteers received either the serotonin-enhancing an...
Source: Guardian Unlimited Science - July 13, 2015 Category: Science Authors: Molly Crockett Tags: Science Psychology Neuroscience Source Type: news

New Study Sheds Light On The Link Between Antidepressants And Birth Defects
A new study from the Centers for Disease Control and Prevention finds that pregnant women who take certain drugs that are part of a class of antidepressants known as SSRIs (selective serotonin reuptake inhibitors) are at slightly increased risk for having a baby with birth defects.  While this sounds frightening, the absolute risk for birth defects is still very low, cautioned study authors. For instance, women who took Paxil (paroxetine) would increase their risk for giving birth to a baby with anencephaly (a serious and often fatal brain and skull defect) from two per 10,000 to seven per 10,000. For a certain heart ...
Source: Science - The Huffington Post - July 10, 2015 Category: Science Source Type: news

Study links Prozac, Paxil use with birth defects
(Reuters) - A sweeping government study of thousands of women has found links between the older antidepressants Prozac and Paxil and birth defects, but has cleared other popular treatments in the class, including Celexa, Lexapro and Pfizer's Zoloft, which is the subject of a major lawsuit over birth defect claims. (Source: Reuters: Health)
Source: Reuters: Health - July 10, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Is your medication affecting your MORALS? Antidepressants make people behave selflessly, while Parkinson’s drugs make you selfish, study claims
Researchers at University College London found that citalopram-takers were willing to pay almost twice as much to prevent harm to others than those given placebo drugs in an experiment. (Source: the Mail online | Health)
Source: the Mail online | Health - July 9, 2015 Category: Consumer Health News Source Type: news

Medical News Today: How do antidepressants affect moral decision-making?
The effects on moral decision-making of citalopram and levodopa - commonly prescribed drugs that affect the brain's levels of serotonin and dopamine - are compared in a new study. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 3, 2015 Category: Consumer Health News Tags: Psychology / Psychiatry Source Type: news

Commonly prescribed drugs affect decisions to harm oneself and others
Healthy people given the serotonin-enhancing antidepressant citalopram were willing to pay almost twice as much to prevent harm to themselves or others than those given placebo drugs in a moral decision-making experiment. In contrast, the dopamine-boosting Parkinson's drug levodopa made healthy people more selfish, eliminating an altruistic tendency to prefer harming themselves over others. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 2, 2015 Category: Science Source Type: news

Commonly prescribed drugs affect decisions to harm oneself and others
(University College London) Healthy people given the serotonin-enhancing antidepressant citalopram were willing to pay almost twice as much to prevent harm to themselves or others than those given placebo drugs in a moral decision-making experiment at UCL. In contrast, the dopamine-boosting Parkinson's drug levodopa made healthy people more selfish, eliminating an altruistic tendency to prefer harming themselves over others. The study was a double-blind randomized controlled trial and the results are published in Current Biology. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 2, 2015 Category: Global & Universal Source Type: news

Common Antidepressants Linked to Higher Fracture Odds in Menopausal Women
Drugs like Celexa, Prozac could undermine bone, research suggests (Source: WebMD Health)
Source: WebMD Health - June 26, 2015 Category: Consumer Health News Source Type: news

Common Antidepressants Linked to Higher Fracture Odds in Menopausal Women
Drugs like Celexa, Prozac could undermine bone, research suggests Source: HealthDay Related MedlinePlus Pages: Antidepressants, Fractures, Menopause (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - June 26, 2015 Category: Consumer Health News Source Type: news

Is It Bedtime for Benzos?
“Bernard also laughed; after two grams of soma the joke seemed, for some reason, good. Laughed and then, almost immediately, dropped off to sleep.” — Aldous Huxley, Brave New World It’s been a tough few years for benzodiazepines, the pharmaceutical industry’s top-selling family of prescription drugs. Tough in every way, that is, except sales: Xanax remains the world’s most popular pill, and U.S. prescriptions for it and other benzos grow by 12 percent every year. It’s their reputation, long enjoyed, as harmless and effective medicines that’s taking a flurry of hits — so...
Source: Science - The Huffington Post - June 25, 2015 Category: Science Source Type: news

A Troubling Potential Link Between Sleep Aids And Mental Illness
In today's "always on," high-stress world, it has become commonplace to turn to over-the-counter sleep aids for a little help with drifting off into dreamland at night. However, that habit, if made a consistent one, could lead to potentially serious damage when it comes to ones mental health. A new study zeroing in on anticholinergic drugs -- a category that includes common non-prescription sleeping aids and antihistamines like Benadryl -- found that the long-term use of such medications in higher doses can lead to an increased risk of developing dementia, including Alzheimer's disease, in the future. It's the f...
Source: Science - The Huffington Post - April 7, 2015 Category: Science Source Type: news

Medication and Anxiety
Medication can be an effective approach for managing various types of anxiety such as panic, hyperarousal, and constant worry. However, contrary to popular belief and subtle messages from pharmaceutical companies, medication is far from a cure. In fact, when it comes to “cures” for most psychiatric conditions, the data tends to support psychotherapy. For example, post-traumatic stress disorder (PTSD) responds very well to psychotherapy, whereas the positive effects of medication are somewhat limited. The same is true for panic disorder. Although certain types of medication are very good at relieving panic sympt...
Source: Psych Central - March 11, 2015 Category: Psychiatry Authors: Bret Moore, PsyD Tags: Anti-anxiety Antidepressants Benzodiazepines Disorders General Medications Panic Disorder anti-anxiety medications Drug Dependency Fear Hyperarousal Sedatives Selective Serotonin Reuptake Inhibitor snri Ssri Substance Abuse Source Type: news

Stimulant May Speed Antidepressant Response Time in ElderlyStimulant May Speed Antidepressant Response Time in Elderly
Methylphenidate combined with the antidepressant citalopram significantly reduced time to depression remission in elderly patients. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 4, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

Excellent review of lipid rescue therapy
3.5 out of 5 stars Intravenous Lipid Emulsion in the Emergency Department: A Systematic Review of Recent Literature. Cao D et al. J Emerg Med 2014 Dec 19 [Epub ahead of print] Abstract This excellent comprehensive review of lipid rescue therapy (LRT) is vitiated only by the unavoidable fact that available clinical evidence  is so inconclusive. As the authors point out, published literature consists mostly of case reports and small case series. The vast majority of these reported cases have good outcomes and reflect positive effects from ILE, but the evidence is marred by multiple confounding variables (such ...
Source: The Poison Review - February 25, 2015 Category: Toxicology Authors: Leon Tags: Medical intralipid lipid emulsion lipid rescue therapy lipid sink Review Source Type: news

Study suggests combination drug therapy to treat depression in the elderly
FINDINGS This new study by researchers at UCLA found that the combination of Ritalin (methylphenidate) and Celexa (citalopram) can accelerate and improve the overall antidepressant effects of the medications in the elderly. Most patients who responded to the combination achieved remission in the first month. The researchers had also hoped to find that the combination would work more quickly and be tolerated better by this elderly population than either drug alone. They found that the combination was working faster, but the side effects and cognitive benefits did not differ between the groups. IMPACT Geriatric depression is...
Source: UCLA Newsroom: Health Sciences - February 24, 2015 Category: Universities & Medical Training Source Type: news

Gut Feelings: Diet, Depression and Bacteria
In another setback for the notion that depression is all in your head, recent research suggests it may be a gut reaction. Literally. Brain has always bested bowel in the body battles for executive organ status. However, the gastrointestinal tract is moving up in the world and recently was labeled the second brain. Laboratories all over the world have been mapping a bi-directional information highway between these two organs called the gut-brain axis. This connection has revealed the gut's influence on a wide range of things, from satiety and obesity to mood and anxiety. Even how we respond to stress is no longer the sole...
Source: Healthy Living - The Huffington Post - February 17, 2015 Category: Consumer Health News Source Type: news

Common anticholinergic drugs like Benadryl linked to increased dementia risk
This study is another reminder to periodically evaluate the all drugs you’re taking. Look at each one to determine if it’s really helping,” says Dr. Sarah Berry, a geriatrician and assistant professor of medicine at Harvard Medical School. “I’ve seen people who have been on anticholinergic medications for bladder control for years and they are completely incontinent. These drugs obviously aren’t helping.” Many drugs have a stronger effect on older people than younger people. With age, the kidneys and liver clear drugs more slowly, so drug levels in the blood remain higher for a lon...
Source: New Harvard Health Information - January 29, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Alzheimer's Disease Drugs and Supplements Mental Health anticholinergic drugs Source Type: news

Pain Research Pubs
2014 Is Already a Record YearI am pleased with the acceleration of publications by Pain Researchers using our Pain Research Markers and Gene Expression Analysis Tools.Here's a sampling of the most recent: Transfection Regent Publications: Lili Hou, Yanfeng Zhang, Yong Yang, Kai Xiang, Qindong Tan, Qulian Guo. Intrathecal siRNA Against GPNMB Attenuates Nociception in a Rat Model of Neuropathic Pain. Journal of Molecular Neuroscience. July 2014...Ten micrograms of siRNA1- GPNMB dissolved in 30 μl i-Fect transfection reagent (Neuromics, Edina, MN, USA) was administered intrathecally once daily for 7 days, starting from 1 d...
Source: Neuromics - August 7, 2014 Category: Neuroscience Tags: gene expression analysis Gene Silencing GPNMB Gene i-Fect pro-Dynorhin Antibody siRNA delivery in-vivo TRPV1 antibodies Source Type: news

Forest Pharmaceuticals failed to warn of fatal birth defects from antidepressant use, lawsuit claims
(NaturalNews) Forest Pharmaceuticals is under fire for causing fatal birth defects with its antidepressant drugs Lexapro [S-(+)-1-[3-(dimethyl-amino) propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile oxalate] and Celexa [-1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran... (Source: NaturalNews.com)
Source: NaturalNews.com - July 28, 2014 Category: Consumer Health News Source Type: news

What Medications Should Be Avoided with Long QT Syndrome?
Discussion Mycoplasma pneumoniae is a frequent cause of pharyngitis, pneumonia and acute bronchitis, but acute otitis media is uncommon. Symptoms are usually self-limited and variable and include cough (non-productive usually but later can be productive), fever, fatigue and occasionally headache. Coryza is rare. Cough can continue for 3 to 4 weeks and can be accompanied by wheezing. Radiographic changes include diffuse infiltrates or focal abnormalities but are variable. Long QT syndrome (LQTS) is a group of disorders that have a prolonged QT interval and a polymorphic ventricular tachycardia. Torsade de pointes (“t...
Source: PediatricEducation.org - July 14, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Citalopram increases the differentiation efficacy of BMSCs into neuronal-like cells
(Neural Regeneration Research) There is evidence that selective serotonin reuptake inhibitor antidepressants can promote neuronal cell proliferation and enhance neuroplasticity both in vitro and in vivo. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 10, 2014 Category: Global & Universal Source Type: news