Prevalence of Advanced Heart Failure in the Obese Population: A Study From the National Inpatient Sample Database
Purpose: The prevalence for obesity and severe obesity are increasing in the United States and other countries around the world. Obesity is a risk factor for heart failure (HF), and advanced stages and progression of HF. Roughly 12.5% of HF is attributable to obesity. The purpose of this study is to evaluate the prevalence of advanced heart failure (AHF) and cardiogenic shock (CS) in hospitalized patients in the United States according to their body mass index (BMI). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: F.A. Napoli, R. Aleman, D.A. Baran, J.L. Navia, C.A. Sheffield, M.A. Velez, J.A. Estep, Source Type: research

Cardiogenic Shock Due to Culture Negative Mitral Valve Endocarditis
We present a case of culture negative endocarditis in a young patient who presented in cardiogenic shock (CS) and was bridged with temporary mechanical circulatory support (MCS) including veno-arterial extra corporeal membrane oxygenation (VA-ECMO) to mitral valve replacement (MVR) which was complicated by paravalvular abscess. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , I. Vavilin, E. Sarin, Q. Zhao, K. Kumaran, S. Sinha Source Type: research

Post-Transplant Outcome in Recipients on Veno-Arterial Extracorporeal Membrane Oxigenation
Purpose: when cardiogenic shock (CS) complicates heart failure (HF), early support is required to reverse hypoperfusion and organ damage. Bridging CS recipients with veno-arterial extracorporeal membrane oxygenation (ECMO) prioritizes list status. We retrospectively evaluated the outcome of patients (PT) transplanted on ECMO at our center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: G. Masciocco, , G. Olivieri, M. Varrenti, S. Ghidini, N. Conti, M. Palazzini, A. Verde, A. Garascia, M. Mondino, C. Russo Source Type: research

Role of Tmcs with Impella as Bridge to LVAD After AMI Related Cardiogenic Shock
Purpose: Implantation of durable left ventricular assist device (LVAD) in cardiogenic shock (CS) patients after acute myocardial infarction (AMI) presents specific challenges (small left ventricular size, acute infarct area, antithrombotic therapy, status INTERMACS 1 with impaired organ function and derangements in coagulation and inflammatory parameters.). The aim of this study was to analyzed feasibility, timing and outcomes of durable LVAD implantation after tMCS with Impella due to AMI CS. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: S. Ajello, M. Pieri, S. Dormio, L. Baldetti, S. Altizio, F. Consolo, P. Nardelli, A. Ortalda, Source Type: research

GDMT in Patients on Impella 5.0/5.5 Support: Feasibility and Trend Over Time
Purpose: Guideline-directed medical therapy (GDMT) for heart failure (HF), encompassing 4 medication classes, is recommended in acute HF patients during hospitalization after clinical stability is achieved. Data concerning timing and safety of administration of these drugs in patients on temporary mechanical (tMCS) circulatory support are lacking. We reviewed the experience with the use of GDMT in patients supported with Impella 5.0/5.5 for cardiogenic shock who experienced recovery of native heart. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M. Pieri, L. Baldetti, S. Altizio, P. Nardelli, A. Ortalda, E. Fominskiy, S. Ajello, Source Type: research

Cardiac Shock and ECMO: Does Etiology Matter?
This study aims to describe the 1 year outcome of VA-ECMO for cardiogenic shock with regards to etiology, as well as to try to identify predictors for mortality at our centre. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Westerlind, I. Lepore Lagerberg, G. Dellgren Source Type: research

Sublingual Microcirculation in Acute Mechanical Circulatory Support in Cardiogenic Shock
The objective of our study was to characterize the impact of different AMCS devices on the microcirculation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , C. Lee, J. Baranowska, C. Moeller, A. Fernandez Valledor, G. Rubinstein, D. Oren, T. Miller, D. Lotan, A. Rahman, Y. Kaku, J. Raikhelkar, K. Takeda, E. DeFilippis, M. Yuzefpolskaya, P. Colombo, D. Majure, K. Clerkin, D. Burkhoff, G. Sayer, N. Uriel, J. Source Type: research

Impact of Cardiogenic Shock Etiology on the Relationship Between Systemic Vascular Resistance and Mortality
Purpose: Cardiogenic shock (CS) pathophysiology may differ between patients with an acute myocardial infarction (AMI-CS) and those with decompensated heart failure (HF-CS). We sought to understand whether the relationship between low systemic vascular resistance (SVR) and CS mortality differs by AMI-CS vs HF-CS. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K. Wartgow, C. Mackenzie, M. Chavez, M. Scott, E. Sheffield, C. Kyriakopoulos, I. Taleb, E. Dranow, M. Goodwin, E. Maneta, R. Hamouche, J. Fang, S. Drakos, T. Hanff Source Type: research

Outcomes of Transport on Venoarterial Extracorporeal Life Support in Cardiogenic Shock Patients
Purpose: Venoarterial extracorporeal life support (VA-ECLS) can be utilized to transport cardiogenic shock patients from a regional to a tertiary center. The purpose of this study was to compare the outcomes of patients transferred to a tertiary center from regional centers on VA-ECLS with those who had VA-ECLS placed at the tertiary center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , I. Feng, A. Vinogradsky, J.R. Gower, M. Biscotti, M. Yuzefpolskaya, P. Colombo, G. Sayer, N. Uriel, Y. Kaku, J. Fried, K. Takeda Source Type: research

Short to Mid-Term Outcomes in Patients Bridged to Recovery Using Impella 5.5
Purpose: In the setting of cardiogenic shock, Impella 5.5 is increasingly utilized as a minimally invasive bridge to recovery, decision, durable left ventricular assist device, or heart transplantation. We studied our short to mid-term experience with patients weaned from Impella 5.5. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: E. Faridmoayer, G. Dardik, T.R. Powley, A.P. Lin, M. Biscotti, J.R. Gower, J.A. Fried, M. Yuzefpolskaya, P.C. Colombo, G.T. Sayer, N. Uriel, G. Ferrari, K. Takeda, Source Type: research

Practice Variation in Temporary MCS Device Choice in Cardiogenic Shock
This study aims to quantify the degree of initial MCS device choice variation in CS and identify associated factors. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Bahl, M. Kanwar, B. Li, S. Sinha, J. Hernandez Montfort, Q. Kong, P. Sangal, D. Burkhoff, C. Mahr, N. Kapur Source Type: research

Association of ECMO Flow Index and Mortality in Adults with Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation: An ELSO Registry Analysis
Purpose: The aim of the study was to determine whether the initial ECMO flow rate is associated with mortality in adults with cardiogenic shock (CS) receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) without concomitant left ventricular mechanical unloading (LVMU). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , L. Aguilar, K. Kennedy, J.A. Fried, K. Takeda, A.J. Kirtane, N.K. Kapur, J.E. Tonna, P. Quintero, M. Sabe, J.E. Ho, R. Sriwattanakomen, L. Labrada, A.S. Rali, A.R. Garan, E.W. Grandin Source Type: research

Clinical Outcomes and the Impact of SCAI Stage Among Protekduo Right Ventricular Assist Device Recipients with Cardiogenic Shock: A Report from the Cardiogenic Shock Working Group
Purpose: The ProtekDuo is a dual-lumen cannula used to provide mechanical circulatory support (MCS) for right heart failure (RHF) in patients with cardiogenic shock (CS). It can be used for primary RHF or in those with biventricular failure, concomitant with an LV support device. Real world data evaluating outcomes in patients supported with the ProtekDuo remain limited by small numbers and a lack of correlation with outcomes. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , M. Kanwar, A. Garan, S. Sinha, P. Sangal, Q. Kong, B. Li, K. Walec, P. Zazzali, D. Burkoff, N. Kapur Source Type: research

Methods and Preliminary Results of Implementation of Multi-Center Earlyimpella ® Support in Patients with St-Segment Elevation Myocardial Infarction Complicated by Cardiogenic Shock (RECOVER IV) Trial Under Exception from Informed Consent
Purpose: Cardiogenic shock (CS) is end-organ hypoperfusion due to reduced cardiac output (CO). ~50% of patients with CS and acute myocardial infarction die before discharge. Drugs or devices can improve CO. We do not know if temporary mechanical circulatory support (MCS) improves long-term survival. Few trials have enrolled patients with CS in the United States (US) in part due to difficulties obtaining informed consent. The prognosis of patients with CS who are able to consent for research differs from those who are not, so consent-based trials may bias estimates of treatment. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: G. Nichol, N. Dickert, K. Adams, D. Morse, S. Morse, C. Facemire, K. Shah, S. Dasari, J. Bodnar, , W. O'Neill, G.W. Stone Source Type: research

Relationship of Systemic Vascular Resistance with Mortality in Cardiogenic Shock
Purpose: Cardiogenic shock (CS) in-hospital mortality remains close to 40%. Loss of compensatory vasoconstriction in more severe CS may accelerate circulatory collapse and death, even when sepsis is excluded. We sought to investigate whether lower systemic vascular resistance in CS is associated with a higher Society for Cardiovascular Angiography& Interventions (SCAI) stage and increased risk of in-hospital mortality. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S. Monte, E. Sheffield, M. Anderson, B. Kogelachatz, J. Leon, I. Taleb, C. Kyriakopoulos, E. Dranow, M. Goodwin, E. Maneta, R. Hamouche, J. Fang, S. Drakos, T. Hanff Source Type: research