Methods and Preliminary Results of Implementation of Multi-Center Earlyimpella ® Support in Patients with St-Segment Elevation Myocardial Infarction Complicated by Cardiogenic Shock (RECOVER IV) Trial Under Exception from Informed Consent

Purpose: Cardiogenic shock (CS) is end-organ hypoperfusion due to reduced cardiac output (CO). ~50% of patients with CS and acute myocardial infarction die before discharge. Drugs or devices can improve CO. We do not know if temporary mechanical circulatory support (MCS) improves long-term survival. Few trials have enrolled patients with CS in the United States (US) in part due to difficulties obtaining informed consent. The prognosis of patients with CS who are able to consent for research differs from those who are not, so consent-based trials may bias estimates of treatment.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research