Impella Malrotation Adversely Impacts Hemodynamics in Cardiogenic Shock
We reported that Impella malrotation within the left ventricle (LV) is common among patients treated with this device for cardiogenic shock (CS). Malrotation was associated with higher rates of aortic and mitral regurgitation worsening during support, raising concern of suboptimal LV unloading in this circumstance. Therefore, we aimed to explore the association of Impella malrotation with the hemodynamic trajectory of CS patients supported with this device. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , D. Romagnolo, M. Festi, A. Beneduce, A.D. Frias, M. Gramegna, S. Sacchi, F. Calvo, V. Pazzanese, M. Pieri, S. Ajello, A. Scandroglio Source Type: research

Impact of Cumulative Vasopressor and Inotrope Medications on Outcomes in Cardiogenic Shock: A Cardiogenic Shock Working Group Report
Purpose: There is a paucity of data on the prognostic implication of vasoactive medications on mortality in cardiogenic shock (CS). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: S. Vallabhajosyula, A. Faugno, B. Li, S. Sinha, J. Hernandez Montfort, M. Kanwar, A.R. Garan, G. Hickey, J. Abraham, C. Mahr, P. Sangal, Q. Kong, A. Khalif, K. Walec, P. Zazzali, R. Kataria, M. Pahuja, V. Blumer, V. Ton, N. Harwani, D. Wencker, S. Nathan, Source Type: research

Temporal Trends of Vasopressor and Inotrope Use in Cardiogenic Shock: A Cardiogenic Shock Working Group Report
Purpose: There remains a paucity of the temporal use and total vasoactive medication requirements for cardiogenic shock (CS) patients in the contemporary era. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: S. Vallabhajosyula, A. Faugno, B. Li, S. Sinha, J. Hernandez Montfort, M. Kanwar, A.R. Garan, G. Hickey, J. Abraham, C. Mahr, P. Sangal, Q. Kong, A. Khalif, K. Walec, P. Zazzali, R. Kataria, M. Pahuja, V. Blumer, V. Ton, N. Harwani, D. Wencker, S. Nathan, Source Type: research

Regional Systems of Care in Cardiogenic Shock Can Improve Outcomes: Penn Medicine Shock Team and Community Relationships
Purpose: Outcomes in patients (PTs) with cardiogenic shock (CS) remain poor. Multidisciplinary approach to the care of PTs with CS can lead to early deployment of advanced care to improve outcomes. Current applications of shock care show unidirectional care from the community to advanced centers. The Penn Medicine Shock Team (PMST) was established in November 2019 with a philosophy of bidirectional communication that leads to strong relationships with community partners. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Parikh, W. Clay, A. Brown, A. Spelde, K. Hoenisch, S. Olia, J. Giri, D. Frankel, E. Gordon, M. Cevasco, C. Bermudez Source Type: research

Pre-Operative INTERMACS Profile as a Predictor of Outcomes in Durable LVAD Patients in the Modern Era
Purpose: Prior studies have demonstrated a link between a patient ’s Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) profile and predicting patient outcomes; however, more current analyses are required to ascertain its continued applicability. We aimed to reassess the prognostic value of the INTERMACS classification system as an in dicator of outcomes in patients presenting with cardiogenic shock utilizing a modern dataset. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A.M. Pico, A. Ramsay, K. Drezek, T. Winship, D. D'Alessandro, G. Lewis, V. Ton, E. Michel, E. Coglianese Source Type: research

Outcome of Implementation of a Cardiogenic Shock Program in a Large Quaternary Center
Purpose: Cardiogenic shock (c shock) is a complication of both acute MI and acute on chronic heart failure with mortality as high as 50-80% which has not changed significantly over the past two decades. A multidisciplinary approach with implementation of a c shock program for the care of these critically ill patients has been shown to significantly improve survival. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , D. Rinde-Hoffman, L. Schnell, M. Sevillano Source Type: research

Let Us Shock You! Multidisciplinary Team Approach to Cardiogenic Shock Improves Patient Outcomes and Reduces Complications
Purpose: Cardiogenic shock (CS) patients experience high mortality, complication rates, and require resource-intensive care. Modes of care delivery with proven benefit for these patients have become increasingly complex and reliant on temporary mechanical circulatory support (tMCS) devices. Our team felt it was critical to develop a quality scorecard to demonstrate meaningful improvements in survival to tMCS explant and discharge by enacting protocol-driven, physician-led, nurse coordinated care for CS patients [1]. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: J. Hajj, A. Kilic, B. Houston, A. Carnicelli, L. Witer, J.D. McMurray, L. Bunting, , M. Summer, J. Yourshaw Source Type: research

Heparin Free Zone: 100 Days of Impella 5.5 Support with Argatroban in a Patient with HIT
We describe a patient in acute cardiogenic shock with heparin induced thrombocytopenia (HIT) who was transitioned to an Impella 5.5 and supported for 100 days with argatroban and no heparin until heart transplantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: J.S. Newman, V. Demekhin, G.L. Piper, , O. Haddad, Z. Kon, C. Saikus Source Type: research

Pulmonary Arterial Pulsatility Index Predicts Mechanical Circulatory Support Following Heart Transplantation
Purpose: The incidence of MCS for early graft dysfunction (EGD) following heart transplantation varies from 2.3% - 28.2%. Low pulmonary pulsatility index (PAPi) is associated with higher mortality in advanced heart failure and cardiogenic shock. We hypothesised that a lower PAPi following heart transplantation is associated with MCS use for EGD. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: I. Yim, S. Pettit, S. Bhagra, M. Berman, N. Drury, Source Type: research

Low Flow Alarms in Disguise: Unraveling the Mystery of Extrinsic Outflow Graft Obstruction
Introduction: Left ventricular assist device (LVAD) pump thrombosis is a serious adverse event. Its clinical presentation is variable ranging from insidious onset of low flow alarms to cardiogenic shock. Although Heart Mate 3 (HM3) devices have significant lower rates of pump thrombosis, outflow graft obstruction should remain on the differential of low flow alarms. Here, we present a patient with a HM3 LVAD who presented with low flow alarms and was found to have outflow graft obstruction due to extrinsic compression. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , D. Jagasia, K. Sidhu, S.B. Prenner, M. Genuardi, V. Ferrari, H. Vidula, T. Wang Source Type: research

Impella 5.5 for Frailty and SCAI D-E Shock: Impact on Post-OHT Oucomes
We present a single-center retrospective cohort study investigating the use of Impella in patients deemed frail prior to transplantation. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: R. Barriola Rubarth, E. Margolin, M. Fortich, M. Woodham, N. Reddy, , H. Tran Source Type: research

Fulminant Lymphocytic Myocarditis with Acute Biventricular Failure: The Role of Mechanical Circulatory Support
Introduction: Fulminant lymphocytic myocarditis (FLM) frequently leads to severe outcomes, such as cardiogenic shock (CS), ventricular tachyarrhythmias, or bradyarrhythmias, which can have an acute and fatal course. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: A. Aijaz, S. Shoukat, R. Sharma, S. Farooq, H. Ashraf, B. Akkanti, I. Hussain, , S. Nathan, M. Patel, I. Gregoric, B. Kar Source Type: research

Massive Left Ventricular Pseudoaneurysm Presenting as Cardiogenic Shock Following Myocardial Infarction
Introduction: A patient with recent inferoposterior myocardial infarction (MI) developed cardiogenic shock (CS) from an LV pseudoaneurysm, successfully managed with surgical intervention. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , E. Flattery, R. Donnino, N. Narula, R.I. Goldberg, A. Galloway, S. Bernard Source Type: research

Prevalence of Advanced Heart Failure in the Obese Population: A Study From the National Inpatient Sample Database
Purpose: The prevalence for obesity and severe obesity are increasing in the United States and other countries around the world. Obesity is a risk factor for heart failure (HF), and advanced stages and progression of HF. Roughly 12.5% of HF is attributable to obesity. The purpose of this study is to evaluate the prevalence of advanced heart failure (AHF) and cardiogenic shock (CS) in hospitalized patients in the United States according to their body mass index (BMI). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: F.A. Napoli, R. Aleman, D.A. Baran, J.L. Navia, C.A. Sheffield, M.A. Velez, J.A. Estep, Source Type: research

Cardiogenic Shock Due to Culture Negative Mitral Valve Endocarditis
We present a case of culture negative endocarditis in a young patient who presented in cardiogenic shock (CS) and was bridged with temporary mechanical circulatory support (MCS) including veno-arterial extra corporeal membrane oxygenation (VA-ECMO) to mitral valve replacement (MVR) which was complicated by paravalvular abscess. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , I. Vavilin, E. Sarin, Q. Zhao, K. Kumaran, S. Sinha Source Type: research