Immediate inflammatory response to mechanical circulatory support in a porcine model of severe cardiogenic shock
In selected cases of cardiogenic shock, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is combined with trans valvular micro axial flow pumps (ECMELLA). Observational studies indicate that ECMELL... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 22, 2024 Category: Surgery Authors: Emilie Gregers, Peter H. Frederiksen, Nanna L. J. Udesen, Louise Linde, Ann Banke, Amalie L. Povlsen, Jeppe P. Larsen, Christian Hassager, Lisette O. Jensen, Jens F. Lassen, Henrik Schmidt, Hanne B. Ravn, Peter M. H. Heegaard and Jacob E. M øller Tags: Research Articles Source Type: research
The Case | Acute kidney injury in a patient with systemic necrotizing lesions
A 41-year-old male patient, who had been experiencing joint pain and weakness for the past 3 weeks, was admitted to the intensive care unit because of vasoplegic and cardiogenic shock, accompanied by multiorgan failure. Before the rapid deterioration of his clinical condition, his kidney function was normal (serum creatinine level, 89 μmol/l), with no proteinuria or hematuria. (Source: Kidney International)
Source: Kidney International - April 18, 2024 Category: Urology & Nephrology Authors: S ébastien Kissling, Samuel Rotman, Fadi Fakhouri Tags: Make Your Diagnosis Source Type: research
Extracorporeal membrane oxygenation (ECMO) during aplasia: A bridge towards myopericarditis recovery after autologous hematopoietic stem cell transplant for systemic sclerosis and recent Coronarovirus disease (COVID-19) vaccination
This report illustrates, for the first time to our knowledge, that ECMO can be indicated despite aplasia during aHSCT and successfully used as a bridge towards heart function recovery in highly selected and fragile AD patients. We review the factors that may contribute to endothelial and myocardial stunning and acute reversible cardiac failure in SSc and aggravate intrinsic endothelial injury during the aHSCT procedure. These classically include: cyclophosphamide drug toxicity, viral infections and autoimmune activation with disease flair per se. In the COVID-19 pandemic times, acute myocarditis due to recent viral infecti...
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Carlotta Cacciatore Mathilde Baudet Estelle Jean Simona Presente Marylou Para Romain Sonneville Dimitri Arangalage Nassim Ait Abdallah Flore Sicre de Fontbrune Pedro Henrique Prata Benjamin Crichi Baptiste Hervier Nathalie Parquet Gilles Soulat Elie Mouss Source Type: research
Prediction of cardiac worsening through to cardiogenic shock in patients with acute heart failure
ConclusionsHalf of patients admitted with AHF experience WHF or new-onset CS. Chronic kidney disease, tricuspid valve regurgitation, and elevated pro-adrenomedullin concentrations predict these events. They could potentially serve as early warning signs for further deterioration in AHF patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 18, 2024 Category: Cardiology Authors: Benedikt N. Beer,
Caroline Kellner,
Jonas Sundermeyer,
Lisa Besch,
Angela Dettling,
Paulus Kirchhof,
Stefan Blankenberg,
Christina Magnussen,
Benedikt Schrage Tags: Original Article Source Type: research
Feasibility and safety of transcaval venoarterial extracorporeal membrane oxygenation in severe cardiogenic shock
EuroIntervention. 2024 Apr 15;20(8):e511-e513. doi: 10.4244/EIJ-D-23-01046.NO ABSTRACTPMID:38629421 | DOI:10.4244/EIJ-D-23-01046 (Source: EuroIntervention)
Source: EuroIntervention - April 17, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Gennaro Giustino Brian P O'Neill Dee Dee Wang Tiberio Frisoli Jonathan X Fang Pedro Engel-Gonzalez James Lee Raef Fadel William W O'Neill Pedro A Villablanca Source Type: research
Feasibility and safety of transcaval venoarterial extracorporeal membrane oxygenation in severe cardiogenic shock
EuroIntervention. 2024 Apr 15;20(8):e511-e513. doi: 10.4244/EIJ-D-23-01046.NO ABSTRACTPMID:38629421 | PMC:PMC11017219 | DOI:10.4244/EIJ-D-23-01046 (Source: EuroIntervention)
Source: EuroIntervention - April 17, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Gennaro Giustino Brian P O'Neill Dee Dee Wang Tiberio Frisoli Jonathan X Fang Pedro Engel-Gonzalez James Lee Raef Fadel William W O'Neill Pedro A Villablanca Source Type: research
Acute Heart Valve Emergencies
Within the cardiac intensive care unit, prompt recognition of severe acute valvular lesions is essential because hemodynamic collapse can occur rapidly, especially when cardiac chambers have not had time for compensatory remodeling. Within this context, optimal medical management, considerations for temporary mechanical circulatory support and decisive treatments strategies are addressed. Fundamental concepts include an appreciation for how sudden changes in flow and pressure gradients between cardiac chambers can impact hemodynamic and echocardiographic findings differently compared to similarly severe chronic lesions, as...
Source: Cardiology Clinics - April 16, 2024 Category: Cardiology Authors: Ryan R. Keane, Venu Menon, Paul C. Cremer Source Type: research
Mechanical Circulatory Support in Cardiogenic Shock
Cardiogenic shock is a lethal condition with significant morbidity, characterized by myocardial insults leading to low cardiac output and ensuing systemic hypoperfusion. While mortality rates remain high, we have improved upon our recognition and definition of cardiogenic shock, now with an emphasis on defining stages of shock to help guide effective treatment strategies with either pharmacologic or mechanical circulatory support. In this review, the authors summarize these stages as well as discuss indications, function, selection, and troubleshooting of the various temporary mechanical circulatory support devices. (Sourc...
Source: Cardiology Clinics - April 16, 2024 Category: Cardiology Authors: Ian Persits, Ran Lee Source Type: research
Intravenous antiplatelet therapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
AbstractThe use of intravenous antiplatelet therapy during primary percutaneous coronary intervention (PPCI) is not fully standardized. The aim is to evaluate the effectiveness and safety of periprocedural intravenous administration of cangrelor or tirofiban in a contemporary ST-segment elevation myocardial infarction (STEMI) population undergoing PPCI. This was a multicenter prospective cohort study including consecutive STEMI patients who received cangrelor or tirofiban during PPCI at seven Italian centers. The primary effectiveness measure was the angiographic evidence of thrombolysis in myocardial infarction (TIMI) flo...
Source: Journal of Thrombosis and Thrombolysis - April 13, 2024 Category: Hematology Source Type: research
ECMO for drug ‐refractory electrical storm without a reversible trigger: a retrospective multicentric observational study
ConclusionsVA-ECMO bridged drug-refractory ES without a reversible trigger with a high success rate. This required prolonged hospital stays and coordination between the ECMO centre, the electrophysiology laboratory, and the heart transplant programme. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 12, 2024 Category: Cardiology Authors: Isabel Dur ães‐Campos,
Catarina Costa,
Ana Rita Ferreira,
Carla Basílio,
Pau Torrella,
Aida Neves,
Ana Margarida Lebreiro,
Gonçalo Pestana,
Luís Adão,
José Pinheiro‐Torres,
Miguel Solla‐Buceta,
Jordi Riera,
Juan Ignacio Chico‐Car Tags: Original Article Source Type: research
A Case of Myocardial Infarction with Non-obstructive Coronary Arteries Complicated by a Ventricular Septal Rupture: The Challenge of Achieving Hemodynamic Stability Using Impella Devices
In this report, we focused on the pathophysiology of MINOCA-related VSR and discussed the effectiveness of Impella devices as a bridge to surgical repair and circulatory backup during the perioperative period.PMID:38599873 | DOI:10.2169/internalmedicine.2945-23 (Source: Internal Medicine)
Source: Internal Medicine - April 10, 2024 Category: Internal Medicine Authors: Masashi Yokoi Tsuyoshi Ito Yu Kawada Junki Yamamoto Toshiyuki Yamada Shohei Kikuchi Shuichi Kitada Toshihiko Goto Hideo Hattori Hisao Suda Yoshihiro Seo Source Type: research
Oxygenation management during veno-arterial ECMO support for cardiogenic shock: a multicentric retrospective cohort study
Hyperoxemia is common and associated with poor outcome during veno-arterial extracorporeal membrane oxygenation (VA ECMO) support for cardiogenic shock. However, little is known about practical daily managemen... (Source: Annals of Intensive Care)
Source: Annals of Intensive Care - April 10, 2024 Category: Intensive Care Authors: Hadrien Winiszewski, Thibault Vieille, Pierre-Gr égoire Guinot, Nicolas Nesseler, Mael Le Berre, Laure Crognier, Anne-Claude Roche, Jean-Luc Fellahi, Nicolas D’Ostrevy, Zied Ltaief, Juliette Didier, Osama Abou Arab, Simon Meslin, Vincent Scherrer, Guil Tags: Research Source Type: research
Cardiogenic shock and chronic kidney disease: Dangerous liaisons
CONCLUSIONS: Cardiogenic shock and CKD are frequent "cross-talking" conditions with limited therapeutic options, resulting in higher rates of death at 1month and 1year. RRT is a strong predictor of death, regardless of preexisting CKD. Multidisciplinary teams involving cardiac and kidney physicians are required to provide integrated care for patients with failure of both organs.PMID:38594150 | DOI:10.1016/j.acvd.2024.01.006 (Source: Archives of Cardiovascular Diseases)
Source: Archives of Cardiovascular Diseases - April 9, 2024 Category: Cardiology Authors: Miloud Cherbi Eric Bonnefoy Etienne Puymirat Nicolas Lamblin Edouard Gerbaud Laurent Bonello Bruno Levy Pascal Lim Laura Muller Hamid Merdji Gr égoire Range Emile Ferrari Meyer Elbaz Hadi Khachab Jeremy Bourenne Marie-France Seronde Nans Florens Guillaum Source Type: research
