Borderline Endometrioid Tumor Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

ASO Visual Abstract: Endometrioid Borderline Ovarian Tumor-Clinical Characteristics, Prognosis, and Management
Ann Surg Oncol. 2022 May 30. doi: 10.1245/s10434-022-11928-z. Online ahead of print.NO ABSTRACTPMID:35637325 | DOI:10.1245/s10434-022-11928-z (Source: Ann Oncol)
Source: Ann Oncol - May 31, 2022 Category: Cancer & Oncology Authors: Giulio Ricotta Amandine Maulard Massimo Candiani Stephanie Scherrier Catherine Genestie Patricia Pautier Alexandra Leary Cyrus Chargari Giorgia Mangili Philippe Morice S ébastien Gouy Source Type: research

Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements
CONCLUSIONS: Peritoneal restaging surgery should be performed if not realized initially, because 5% of EBOTS are diagnosed at stage II-III. Fertility-sparing surgery seems a safe option in selected patients. Because synchronous endometrial diseases, including endometrial carcinoma are frequent, systematic hysterectomy (or endometrial sampling in case of fertility-sparing surgery) is mandatory. Prognosis is generally excellent. Recurrence is a rare event (6%), but it can occur in the form of invasive disease.PMID:35590116 | DOI:10.1245/s10434-022-11893-7 (Source: Ann Oncol)
Source: Ann Oncol - May 19, 2022 Category: Cancer & Oncology Authors: Giulio Ricotta Amandine Maulard Massimo Candiani Stephanie Scherrier Catherine Genestie Patricia Pautier Alexandra Leary Cyrus Chargari Giorgia Mangili Philippe Morice S ébastien Gouy Source Type: research

The cytokeratin 17 expression in primary ovarian tumors has diagnostic but not prognostic significance
AbstractWe assessed the value of cytokeratin 17 (CK17) expression for the differential diagnosis between primary ovarian mucinous tumors and metastases from the gastrointestinal tract (GIT) and the significance of CK17 expression in a broad spectrum of primary ovarian tumors with respect to their prognosis. The sample set consisted of 554 primary ovarian tumors and 255 GIT tumors. In the primary ovarian tumors, a higher CK17 expression (in > 10% of tumors cells) was present only in 0–11.4% of all tumors (including mucinous tumors, micropapillary serous borderline tumors, clear cell, endometrioid, and high-grade ...
Source: Virchows Archiv - May 13, 2022 Category: Pathology Source Type: research

WT1 Positive Ovarian Endometrioid Tumors: Observations From Consult Cases and Strategies for Distinguishing From Serous Neoplasms
We report our experience with 23 ovarian endometrioid neoplasms (4 borderline tumors, 19 carcinomas), mainly received in consultation, which were WT1 positive (diffuse in 11 cases) which often contributed to misdiagnosis. Endometriosis was identified in the same ovary in 6 cases and squamous elements in 7. We describe strategies for distinguishing such neoplasms, which may exhibit morphologic overlap with serous tumors, from low-grade and high-grade serous carcinomas and stress that a diagnosis of HGSC is unlikely with two grossly and histologically normal fallopian tubes. We also stress that a panel of markers should alwa...
Source: International Journal of Gynecological Pathology - March 1, 2022 Category: Pathology Tags: Pathology of the Upper Tract: Original Articles Source Type: research

Müllerian Mucinous Cystadenomas of the Ovary: A Report of 25 Cases of an Unheralded Benign Ovarian Neoplasm Often Associated With Endometriosis and a Brief Consideration of Neoplasms Arising From the Latter
A subset of ovarian mucinous tumors demonstrates müllerian-type epithelium, with such lesions variably designated “endocervical-like” and seromucinous since their popularization based on a report of borderline examples in 1989. While müllerian mucinous borderline tumors and carcinomas have been highlighted in the literature, there has been minimal attention given to benign müllerian mucinous tumors, particularly müllerian mucinous cystadenomas. Given the paucity of literature describing the features of müllerian mucinous cystadenomas/cystadenofibromas, diagnostic difficulties may arise when papillary features are ...
Source: International Journal of Gynecological Pathology - December 17, 2021 Category: Pathology Tags: Pathology of the Upper Tract: Original Articles Source Type: research

Extrauterine Mesonephric-like Neoplasms: Expanding the Morphologic Spectrum
We describe the clinical, pathologic, immunohistochemical, and molecular features of 5 cases of extrauterine mesonephric-like proliferations (4 ovary, 1 extraovarian), all with novel and hitherto unreported features. These include an origin of MLA in extraovarian endometriosis, an association of ovarian MLA with high-grade serous carcinoma, mixed germ cell tumor and mature teratoma, and a borderline ovarian endometrioid tumor exhibiting mesonephric differentiation. Four of the cases exhibited a KRAS variant and 3 also a PIK3CA variant. In reporting these cases, we expand on the published tumor types associated with MLA and...
Source: The American Journal of Surgical Pathology - December 13, 2021 Category: Pathology Tags: Original Articles Source Type: research

Cancers, Vol. 13, Pages 5713: Targeted Selected Reaction Monitoring Verifies Histology Specific Peptide Signatures in Epithelial Ovarian Cancer
ndfeldt Epithelial ovarian cancer (OC) is a disease with high mortality due to vague early clinical symptoms. Benign ovarian cysts are common and accurate diagnosis remains a challenge because of the molecular heterogeneity of OC. We set out to investigate whether the disease diversity seen in ovarian cyst fluids and tumor tissue could be detected in plasma. Using existing mass spectrometry (MS)-based proteomics data, we constructed a selected reaction monitoring (SRM) assay targeting peptides from 177 cancer-related and classical proteins associated with OC. Plasma from benign, borderline, and malignant ovarian tumors...
Source: Cancers - November 15, 2021 Category: Cancer & Oncology Authors: Leena Liljedahl Johan Malmstr öm Bj örg Kristjansdottir Sofia Waldemarson Karin Sundfeldt Tags: Article Source Type: research

Fertility-Sparing Surgery for Ovarian Cancer
J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published in English ...
Source: Clinical Genitourinary Cancer - September 28, 2021 Category: Cancer & Oncology Authors: Geoffroy Canlorbe Nathalie Chabbert-Buffet Catherine Uzan Source Type: research

Fertility-Sparing Surgery for Ovarian Cancer
J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published in English ...
Source: Clinical Breast Cancer - September 28, 2021 Category: Cancer & Oncology Authors: Geoffroy Canlorbe Nathalie Chabbert-Buffet Catherine Uzan Source Type: research

Endometriosis-associated cancer
Climacteric. 2021 Jul 16:1-6. doi: 10.1080/13697137.2021.1948994. Online ahead of print.ABSTRACTEndometriosis will affect about 10% of the female population and not only can it significantly impact adversely on quality of life and result in infertility, but data are accumulating that malignant transformation is an important consideration. Endometriosis can be histologically typical or atypical, ovarian, superficial peritoneal or deep infiltrating. The precursor for malignant transformation appears to be the ovarian atypical endometriosis component. Ovarian cancer is the most important associated cancer, primarily endometri...
Source: Climacteric - July 16, 2021 Category: Geriatrics Authors: F Guidozzi Source Type: research