Mental Health Conditions, Including Depression and Stress, Are Associated with Increased Odds of Gastric Cancer-Insights into the Role of Diet: A Case-Control Study
Nutrients. 2023 Nov 30;15(23):4981. doi: 10.3390/nu15234981.ABSTRACTSeveral risk factors, including nutritional/lifestyle ones, play a role in gastric cancer etiology. Further interactions with mental health have also been emphasized. We hypothesized that individuals with mental disorders would exhibit compromised nutrient intake, increasing their risk of gastric cancer. The state of mental health was evaluated in 82 patients with gastric cancer and 95 healthy controls using the 21-item Depression-Anxiety-Stress Scale. The participants' dietary intakes were evaluated by a 168-item food frequency questionnaire. Based on ful...
Source: Cancer Control - December 9, 2023 Category: Cancer & Oncology Authors: Farhad Vahid Wena Rahmani Sayed Hossein Davoodi Torsten Bohn Source Type: research

Molecules, Vol. 28, Pages 7540: Study of the Anti-Inflammatory Mechanism of & beta;-Carotene Based on Network Pharmacology
In this study, component target prediction was performed by using literature retrieval and the SwissTargetPrediction database. Disease targets were collected from various databases, including DisGeNET, OMIM, Drug Bank, and GeneCards. A protein–protein interaction (PPI) network was constructed, and enrichment analysis of gene ontology and biological pathways was carried out for important targets. The analysis showed that there were 191 unique targets of β-carotene after removing repeat sites. A total of 2067 targets from the three databases were integrated, 58 duplicate targets were removed, and 2...
Source: Molecules - November 11, 2023 Category: Chemistry Authors: Shilin Wu Ran Chen Jingyun Chen Ning Yang Kun Li Zhen Zhang Rongqing Zhang Tags: Article Source Type: research

Network pharmacology-based and molecular docking-based analysis of You-Gui-Yin for the treatment of osteonecrosis of the femoral head
This study is aimed at exploring the possible mechanisms of action of the YGY in the treatment of ONFH based on network pharmacology and molecular docking. TCMSP was used to screen the active components and targets of YGY. The disease targets of ONFH were collected in several public databases. The protein-protein interaction (PPI) Network was constructed using the STRING platform. The Metascape database platform was used for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. The key active components and core target proteins of YGY in the treatment of ONFH were verified by the molecular docking...
Source: Atherosclerosis - October 31, 2023 Category: Cardiology Authors: Zhi-Yuan Yao Shu-Yao Fan Zhou-Feng Song Zhan-Chun Li Source Type: research

Network pharmacology-based and molecular docking-based analysis of You-Gui-Yin for the treatment of osteonecrosis of the femoral head
This study is aimed at exploring the possible mechanisms of action of the YGY in the treatment of ONFH based on network pharmacology and molecular docking. TCMSP was used to screen the active components and targets of YGY. The disease targets of ONFH were collected in several public databases. The protein-protein interaction (PPI) Network was constructed using the STRING platform. The Metascape database platform was used for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. The key active components and core target proteins of YGY in the treatment of ONFH were verified by the molecular docking...
Source: Atherosclerosis - October 31, 2023 Category: Cardiology Authors: Zhi-Yuan Yao Shu-Yao Fan Zhou-Feng Song Zhan-Chun Li Source Type: research

Molecules, Vol. 28, Pages 7177: Antimicrobial and Antioxidant Efficacy of the Lipophilic Extract of Cirsium vulgare
This study discloses the potential antioxidant and antimicrobial activities, including some bioactive components, of Cirsium vulgare and implies that Cirsium vulgare holds possible applications in the food and pharmaceutical industries as an antioxidant, antibacterial, and antifungal agent. (Source: Molecules)
Source: Molecules - October 19, 2023 Category: Chemistry Authors: Mine Ayd ın Kurç Hakime H ülya Orak Dumrul G ülen Hilmican Caliskan Merve Argon Temine Sabudak Tags: Article Source Type: research

Molecules, Vol. 28, Pages 7025: Cytotoxic and Antioxidant Potential of Launaea mucronata Forssk Essential Oil Growing in Northern Saudi Arabia
uk Arafa Musa Essential oils are naturally occurring multicomponent combinations of isoprenoids with distinctive odors that are produced by aromatic plants from mevalonic acid. They are extensively applied in aromatherapy for the treatment of various ailments. To investigate the potential therapeutic value of the ingredients in Launaea mucronata essential oil (EO), gas chromatography–mass spectrometry (GC-MS) analysis was used for essential oil characterization. Then, 2,2-diphenyl-1-picrylhydrazyl (DPPH), β-carotene/linoleic acid, and 2,2′-azino-bis(3-ethylbenzothiazoline-6-su...
Source: Molecules - October 11, 2023 Category: Chemistry Authors: Ehab M. Mostafa Ahmed H. El-Ghorab Mohammed M. Ghoneim Hasnaa Ali Ebrahim Moaz Abulfaraj Mohamed A. Abdelgawad Amr Farouk Arafa Musa Tags: Article Source Type: research

Molecules, Vol. 28, Pages 6873: Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula
oa Supawadee Daodee Supercritical fluid extraction (SFE) is an innovative green technology for the extraction of phytochemicals from plants. Therefore, this study aimed to evaluate the application of SFE and to optimize the extraction conditions of the Thai herbal formula, Kleeb Bua Daeng (KBD). A Box–Behnken design (BBD) with response surface methodology (RMS) was used to determine the effect of the extraction time (30–90 min), temperature (30–60 °C), and pressure (200–300 bar) on response variables including the extraction yield, total phenolic con...
Source: Molecules - September 29, 2023 Category: Chemistry Authors: Nittaya Ngamkhae Orawan Monthakantirat Yaowared Chulikhit Juthamart Maneenet Charinya Khamphukdee Yutthana Chotritthirong Suphatson Limsakul Chantana Boonyarat Supaporn Pitiporn Pakakrong Kwankhao Anake Kijjoa Supawadee Daodee Tags: Article Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research

Immunomodulatory and Antioxidant Properties of < em > Ipomoea batatas < /em > Flour and Extracts Obtained by Green Extraction
In this study, we therefore explored its phytochemistry and its associated bioactivity potential for human health. We analyzed the nutritional composition of orange flesh sweet potato (OFSP) flour and assessed the antioxidant (free radical scavenging) and immunomodulatory (on inflammatory murine macrophages) properties of the extract. More specifically, we measured the impact of OFSP flour extract on mediators such as Nitric Oxide (NO) and the production of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-...
Source: Current Issues in Molecular Biology - September 27, 2023 Category: Molecular Biology Authors: Imane Boukhers Sylvie Morel Joelle Kongolo Romain Domingo Adrien Servent Lea Ollier Hippolyte Kodja Thomas Petit Patrick Poucheret Source Type: research