Molecules, Vol. 29, Pages 1732: Effect of the Drying Method and Storage Conditions on the Quality and Content of Selected Bioactive Compounds of Green Legume Vegetables
This study aimed to determine the effect of the drying method (freeze-drying, air-drying), storage period (12 months), and storage conditions (2–4 °C, 18–22 °C) applied to two legume species: green beans and green peas. The raw and dried materials were determined for selected physical parameters typical of dried vegetables, contents of bioactive components (vitamin C and E, total chlorophyll, total carotenoids, β-carotene, and total polyphenols), antioxidative activity against the DPPH radical, and sensory attributes (overall quality and profiles of color, te...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Piotr G ębczyński Ma łgorzata Tabaszewska Katarzyna Kur Maria Zbylut-G órska Jacek S łupski Tags: Article Source Type: research

Kidney-tonifying blood-activating decoction delays ventricular remodeling in rats with chronic heart failure by regulating gut microbiota and metabolites and p38 mitogen-activated protein kinase/p65 nuclear factor kappa-B/aquaporin-4 signaling pathway
CONCLUSIONS: KTBA decoction manipulates the expression of several key proteins in the p38MAPK/p65NF-κB/AQP4 signaling pathway, modulates gut microbiota and metabolites toward a more favorable profile, improves gut barrier function, delays cardiomyocyte hypertrophy and fibrosis,and improves cardiac function.PMID:38580189 | DOI:10.1016/j.jep.2024.118110 (Source: Cancer Control)
Source: Cancer Control - April 5, 2024 Category: Cancer & Oncology Authors: Rui Xu Yanping Bi Xiaoteng He Yan Zhang Xin Zhao Source Type: research

Molecules, Vol. 29, Pages 1585: A Scoping Review on Carotenoid Profiling in Passiflora spp.: A Vast Avenue for Expanding the Knowledge on the Species
e Oliveira The Passiflora genus is recognised for its ethnopharmacological, sensorial, and nutritional significance. Yet, the screening of its dietary and bioactive molecules has mainly targeted hydrophilic metabolites. Following the PRISMA-P protocol, this review assessed the current knowledge on carotenoid composition and analysis within Passiflora, examining 968 records from seven databases and including 17 studies focusing on carotenoid separation and identification in plant parts. Those publications originated in America and Asia. P. edulis was the most frequently examined species of a total of ten, while pulp was...
Source: Molecules - April 2, 2024 Category: Chemistry Authors: Marina de Macedo Rodrigues Leite Daniele Bobrowski Rodrigues Raquel Brison Fernanda Nepomuceno Maria Lua Bento L ívia de Lacerda de Oliveira Tags: Review Source Type: research

A prospective study of smoking-related white blood cell DNA methylation markers and risk of bladder cancer
Eur J Epidemiol. 2024 Mar 30. doi: 10.1007/s10654-024-01110-y. Online ahead of print.ABSTRACTBladder cancer, a common neoplasm, is primarily caused by tobacco smoking. Epigenetic alterations including DNA methylation have the potential to be used as prospective markers of increased risk, particularly in at-risk populations such as smokers. We aimed to investigate the potential of smoking-related white blood cell (WBC) methylation markers to contribute to an increase in bladder cancer risk prediction over classical questionnaire-based smoking metrics (i.e., duration, intensity, packyears) in a nested case-control study with...
Source: Cancer Control - March 30, 2024 Category: Cancer & Oncology Authors: Roel Vermeulen Barbara Bodinier Sonia Dagnino Rin Wada Xuting Wang Debra Silverman Demetrius Albanes Neal Freedman Mohammad Rahman Douglas Bell Marc Chadeau-Hyam Nathaniel Rothman Source Type: research

A prospective study of smoking-related white blood cell DNA methylation markers and risk of bladder cancer
AbstractBladder cancer, a common neoplasm, is primarily caused by tobacco smoking. Epigenetic alterations including DNA methylation have the potential to be used as prospective markers of increased risk, particularly in at-risk populations such as smokers. We aimed to investigate the potential of smoking-related white blood cell (WBC) methylation markers to contribute to an increase in bladder cancer risk prediction over classical questionnaire-based smoking metrics (i.e., duration, intensity, packyears) in a nested case –control study within the prospective prostate, lung, colorectal, and ovarian (PLCO) Cancer Screening...
Source: European Journal of Epidemiology - March 30, 2024 Category: Epidemiology Source Type: research

Polycystic Ovary Syndrome and Oxidative Stress. Natural Treatments
Curr Med Chem. 2024 Feb 16. doi: 10.2174/0109298673270372231130071320. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is one of the most frequent endocrinopathology affecting women in their reproductive ages. However, PCOS is also related to metabolic abnormalities such as metabolic syndrome (MS), insulin resistance (IR), and type 2 diabetes, among others. Consequently, an inflammatory and pro-oxidative status is also present in these patients, aggravating the syndrome's symptoms. This work aims to discuss some late treatments that focus on oxidative stress (OS) as a central feature related to primary PCOS ...
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Alicia Beatriz Motta Source Type: research

Polycystic Ovary Syndrome and Oxidative Stress. Natural Treatments
Curr Med Chem. 2024 Feb 16. doi: 10.2174/0109298673270372231130071320. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is one of the most frequent endocrinopathology affecting women in their reproductive ages. However, PCOS is also related to metabolic abnormalities such as metabolic syndrome (MS), insulin resistance (IR), and type 2 diabetes, among others. Consequently, an inflammatory and pro-oxidative status is also present in these patients, aggravating the syndrome's symptoms. This work aims to discuss some late treatments that focus on oxidative stress (OS) as a central feature related to primary PCOS ...
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Alicia Beatriz Motta Source Type: research

Polycystic Ovary Syndrome and Oxidative Stress. Natural Treatments
Curr Med Chem. 2024 Feb 16. doi: 10.2174/0109298673270372231130071320. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is one of the most frequent endocrinopathology affecting women in their reproductive ages. However, PCOS is also related to metabolic abnormalities such as metabolic syndrome (MS), insulin resistance (IR), and type 2 diabetes, among others. Consequently, an inflammatory and pro-oxidative status is also present in these patients, aggravating the syndrome's symptoms. This work aims to discuss some late treatments that focus on oxidative stress (OS) as a central feature related to primary PCOS ...
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Alicia Beatriz Motta Source Type: research

Polycystic Ovary Syndrome and Oxidative Stress. Natural Treatments
Curr Med Chem. 2024 Feb 16. doi: 10.2174/0109298673270372231130071320. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is one of the most frequent endocrinopathology affecting women in their reproductive ages. However, PCOS is also related to metabolic abnormalities such as metabolic syndrome (MS), insulin resistance (IR), and type 2 diabetes, among others. Consequently, an inflammatory and pro-oxidative status is also present in these patients, aggravating the syndrome's symptoms. This work aims to discuss some late treatments that focus on oxidative stress (OS) as a central feature related to primary PCOS ...
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Alicia Beatriz Motta Source Type: research

Longitudinal analysis of carotenoid content in preterm human milk
Conclusion Carotenoid content of HM was dynamic and varied between mothers and as lactation progressed. Infant plasma displayed a distinct distribution of carotenoids from HM. (Source: European Journal of Pediatrics)
Source: European Journal of Pediatrics - March 21, 2024 Category: Pediatrics Source Type: research

Molecules, Vol. 29, Pages 1377: Unveiling the Chemical Composition, Bioactive Profile and Antioxidant Capacity of Dried Egyptian Jew & rsquo;s Mallow Stems as a Promising Anticancer Agent
Molecules, Vol. 29, Pages 1377: Unveiling the Chemical Composition, Bioactive Profile and Antioxidant Capacity of Dried Egyptian Jew’s Mallow Stems as a Promising Anticancer Agent Molecules doi: 10.3390/molecules29061377 Authors: Marwa Rashad Ali Huda Hassan Ibrahim Aziza Ali Salah-Eldin Phytochemicals from waste materials generated by agricultural and industrial processes have become globally significant due to their accessibility and potential effectiveness with few side effects. These compounds have essential implications in both medicine and the economy. Therefore, a quantitative analysis of the p...
Source: Molecules - March 20, 2024 Category: Chemistry Authors: Marwa Rashad Ali Huda Hassan Ibrahim Aziza Ali Salah-Eldin Tags: Article Source Type: research

Vitamins C, E, and beta-carotene and risk of type 2 diabetes: a systematic review and meta-analysis
In conclusion, moderate intakes of vitamins C, E, and beta-carotene may lower the risk of T2D by reducing insulin resistance. Lack of protection with supplementation in RCTs suggests that adequate rather than high intakes may play a role in T2D prevention. REGISTRY AND REGISTRY NUMBER FOR SYSTEMATIC REVIEWS OR META-ANALYSES: PROSPERO(CRD42022343482).PMID:38493875 | DOI:10.1016/j.advnut.2024.100211 (Source: Adv Data)
Source: Adv Data - March 17, 2024 Category: Epidemiology Authors: Anna-Maria Lampousi Therese Lundberg Josefin E L öfvenborg Sofia Carlsson Source Type: research

Molecules, Vol. 29, Pages 1259: High-Pressure Processing of Fruit Smoothies Enriched with Dietary Fiber from Carrot Discards: Effects on the Contents and Bioaccessibilities of Carotenoids and Vitamin E
r Böhm The effects of high-pressure processing (HPP) (450 MPa/600 MPa/3 min) on the carotenoid and vitamin E contents of smoothies made from strawberry, orange juice, banana and apple, and the same smoothies enriched with dietary fiber from discarded carrots were compared. The contents and bioaccessibilities of these compounds were also evaluated over the course of 28 days at 4 °C. The application of HPP in the formulations significantly increased the contents of β-cryptoxanthin, α-carotene and β-carotene and retained the contents of lutein, zeaxanthin and vitamin E ...
Source: Molecules - March 12, 2024 Category: Chemistry Authors: Melisa Donda Zbinden Mario Schmidt Charito Ivana Vignatti Mar ía Élida Pirovani Volker B öhm Tags: Article Source Type: research

Cross-cultural adaptation and reproducibility of the EPIC-Norfolk food frequency questionnaire in young people living in Croatia
CONCLUSION: The Croatian version of the EPIC-Norfolk FFQ can be a useful tool for assessing dietary intakes in young people in Croatia and possibly in neighboring countries with similar languages and dietary habits.PMID:38433509 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - March 4, 2024 Category: General Medicine Authors: Erna Davidovi ć Cvetko Ines Drenjan čević Ivana Juki ć Ana Stupin Petar Šušnjara Martina Vulin Martina Kos Matea Luki ć Lorena Stanojevi ć Source Type: research