Predictive factors for recurrence of serious arrhythmias in patients with acute digoxin poisoning - El-Sarnagawy GN, El Sharkawy SI, Helal NE.
Although digoxin poisoning has declined in the past decades, it still has deleterious outcomes. The hallmark of serious life-threatening arrhythmias remains challenging due to its non-specific initial presentation. Therefore, this study aimed to evaluate t... (Source: SafetyLit)
Source: SafetyLit - July 17, 2021 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

More Evidence Epilepsy Tied to Risk for Major CV Events More Evidence Epilepsy Tied to Risk for Major CV Events
Patients with epilepsy are at greater risk for major cardiovascular events, including stroke and clinically significant arrhythmia, new research suggests.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - July 7, 2021 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Traumatic injury and atrial fibrillation among deployed service members - Alcover KC, Ambardar SR, Poltavskiy E, Nasir JM, Janak JC, Howard JT, Walker LE, Haigney MC, Stewart IJ.
In this study, we investigated the impact of traumatic injury on AF/AFL among service members with deployment ... (Source: SafetyLit)
Source: SafetyLit - July 5, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

First case of acute poisoning with amiodarone and flecainide in attempted suicide successfully managed with lipid emulsion therapy in the emergency department: case report and literature review - Bologa C, Lionte C, Popescu A, Sorodoc V, Sorodoc L.
We report a 47-year-old patient admitted to the ED 5 h after... (Source: SafetyLit)
Source: SafetyLit - July 5, 2021 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Polymyositis-Dermatomyositis Tied to Arrhythmias in Young, Middle-Aged Adults Polymyositis-Dermatomyositis Tied to Arrhythmias in Young, Middle-Aged Adults
Young and middle-aged adults with polymyositis-dermatomyositis are more likely to have arrhythmias than matched controls without these rare rheumatic conditions, a US study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 18, 2021 Category: Consumer Health News Tags: Rheumatology News Source Type: news

New Phase 3 Study Results Show IMBRUVICA ® (ibrutinib)-Based Combination Regimen as an All-Oral Fixed-Duration Treatment Demonstrated Superior Progression-Free Survival in Adult Patients with Previously Untreated Chronic Lymphocytic Leukemia
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced primary results from the pivotal Phase 3 GLOW study (NCT03462719) evaluating fixed-duration IMBRUVICA® plus venetoclax (I+V) compared to chlorambucil plus obinutuzumab (Clb+O) for first-line treatment of elderly or unfit patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study demonstrated superior progression-free survival (PFS) of a once-daily, all-oral, fixed-duration regimen of I+V versus Clb+O as first-line treatment of CLL; the study also showed improved duration of re...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

High voltage electrical injuries: outcomes & 1-year follow-up from a level 1 trauma centre - Goyal D, Jagne N, Dhiman A, Patil V, Rattan A.
BACKGROUND: High voltage (>1000 V) electric injuries (HVEI) are rare, and dreaded due to profound myonecrosis and fatal arrhythmias. Trauma Centres are well equipped for acute and definitive treatment of injuries. Paucity of burn centres in Himalayan belt ... (Source: SafetyLit)
Source: SafetyLit - June 9, 2021 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Space travel weakens our immune systems: Now scientists may know why
(University of California - San Francisco) Microgravity in space perturbs human physiology and is detrimental for astronaut health, a fact first realized during early Apollo missions when astronauts experienced inner ear disturbances, heart arrhythmia, low blood pressure, dehydration, and loss of calcium from their bones after their missions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 7, 2021 Category: International Medicine & Public Health Source Type: news

What Are Some Indications for Using Dexamethasone?
Discussion Corticosteroids are a group of drugs which can be naturally or synthetically produced. Naturally occurring substances are produced in the adrenal gland, and are protein-bound (primarily corticosteroid-binding globulin and albumin). In the target tissues, they may need to be converted to an active substance. They are then reduced, oxidized, hydroxylated or conjugated as measures to inactivate them. Synthetic steroids have less protein binding and depending on their structure are more or less resistant to inactivation. Prednisone is the glucocorticoid most often used for treatment, especially as it has a short hal...
Source: PediatricEducation.org - June 7, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A comp...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Childhood abuse and social anxiety symptoms among young adults: moderating role of respiratory sinus arrhythmia suppression to social stress - Ji H, Lu W.
BACKGROUND: Childhood abuse (CA) has been considered as an environmental risk factor for the development of social anxiety symptoms. Respiratory sinus arrhythmia (RSA) is a biomarker that has been found to interact with environmental stressors to affect ps... (Source: SafetyLit)
Source: SafetyLit - May 24, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

IMBRUVICA ® (ibrutinib)-Based Combination Regimen as a Fixed-Duration, First-Line Treatment for Chronic Lymphocytic Leukemia Demonstrates High Rates of Disease Control
May 19, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the fixed-duration cohort of the investigational Phase 2 CAPTIVATE study, showing that 95 percent of patients treated with combined IMBRUVICA® plus venetoclax were alive and progression-free at two years.[1] Deep remissions were seen across all subgroups, including patients with high-risk chronic lymphocytic leukemia (CLL).1 In addition, long-term data from the RESONATE-2 (PCYC-1115/1116) study will be presented, providing the longest follow-up Phase 3 data for any BTK inhibitor to date. These data ...
Source: Johnson and Johnson - May 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Compound may prevent risk of a form of arrhythmia from common medications
(Washington University in St. Louis) The team discovered a compound that prevents and even reverses the underlying physiological change that can lead some drugs to cause heart problems. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 14, 2021 Category: International Medicine & Public Health Source Type: news

Death Risk Up for Hospitalized Cannabis Users With Arrhythmias
THURSDAY, May 13, 2021 -- Hospitalized patients who use cannabis and have an arrhythmia have worse outcome than cannabis users without arrhythmias, according to a study presented at EHRA 2021, an online scientific congress hosted by the European... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 13, 2021 Category: Pharmaceuticals Source Type: news

Greater effectiveness in the treatment of arrhythmia with radio frequency energy and catheterization
(Universitat Pompeu Fabra - Barcelona) An article published in International Journal of Hyperthermia proposes a more effective protocol for the treatment of cardiac arrhythmias when applying radiofrequency energy at the site of the arrhythmia by catheterization. The research results from the final year project on the bachelor's degree in Biomedical Engineering by Sergi Coderch Navarro, supervised by Ana Gonz á lez Su á rez and Oscar Camara, researchers with the PhySense group of the BCN MedTech Research Unit. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 6, 2021 Category: International Medicine & Public Health Source Type: news