Reporting of R 2 Statistics for Mixed-Effects Regression Models
To the Editor We read with interest the article by Andorra et al that evaluated the dynamics of brain volume loss in multiple sclerosis and modeled these variables in mixed-effects regression models as functions of disease duration. The authors report various goodness-of-fit measures of their models, focusing on the coefficient of determination (R2), which ranges from 0 to 1 and represents the proportion of variance in the dependent variable explained by the model. For a model such as ordinary least squares regression, which includes only fixed-effects components, the interpretation of theR2 is intuitive and represents the...
Source: JAMA Neurology - February 4, 2019 Category: Neurology Source Type: research
Laparoscopic Transduodenal Ampullectomy for Ampullary Tumor
Publication date: Available online 20 December 2018Source: Cirugía Española (English Edition)Author(s): Esteban Cugat Andorrà, Eric Herrero Fonollosa, Maria Isabel García Domingo, Judith Camps Lasa (Source: Cirugia Espanola)
Source: Cirugia Espanola - December 21, 2018 Category: Surgery Source Type: research
Autologous Falciform Ligament Graft for Vascular Reconstruction in Pancreatic Cancer Surgery
Publication date: Available online 10 December 2018Source: Cirugía Española (English Edition)Author(s): María Galofré-Recasens, Eric Herrero Fonollosa, Judith Camps Lasa, María Isabel García-Domingo, Esteban Cugat Andorrà (Source: Cirugia Espanola)
Source: Cirugia Espanola - December 11, 2018 Category: Surgery Source Type: research
Laparoscopic transduodenal ampullectomy for ampullary tumor.
PMID: 30482393 [PubMed - as supplied by publisher] (Source: Cirugia eEspanola)
Source: Cirugia eEspanola - November 24, 2018 Category: Surgery Authors: Cugat Andorrà E, Herrero Fonollosa E, García Domingo MI, Camps Lasa J Tags: Cir Esp Source Type: research
[The design of a population register on cerebral palsy: its application and analysis in Andorra and Navarre].
CONCLUSIONS: The use of population registers allows a better knowledge of cerebral palsy as well as the evaluation and development of prevention strategies and optimization of care resources with objective data. It is necessary to generalize the use of this type of records in our environment.
PMID: 30047119 [PubMed - in process] (Source: Revista de Neurologia)
Source: Revista de Neurologia - July 27, 2018 Category: Neurology Authors: Avellanet M, Mena A, Aisa-Pardo E Tags: Rev Neurol Source Type: research
Magnetic resonance markers of tissue damage related to connectivity disruption in multiple sclerosis
In conclusion, patients with MS exhibit decreased structural network efficiency driven by diffuse microstructural impairment of the WM, probably related to demyelination, astroglial and neuroaxonal damage. The accumulation of neuroaxonal pathological burden seems to magnify the risk of global network collapse, while demyelination may contribute to the regional disorganization. These network modifications have negative consequences on cognition. (Source: NeuroImage: Clinical)
Source: NeuroImage: Clinical - July 13, 2018 Category: Radiology Source Type: research
Autologous falciform ligament graft for vascular reconstruction in pancreatic cancer surgery.
PMID: 30007580 [PubMed - as supplied by publisher] (Source: Cirugia eEspanola)
Source: Cirugia eEspanola - July 12, 2018 Category: Surgery Authors: Galofré-Recasens M, Herrero Fonollosa E, Camps Lasa J, García-Domingo MI, Cugat Andorrà E Tags: Cir Esp Source Type: research
Analyzing the Local Epidemiological Profile of Malaria Transmission in the Brazilian Amazon Between 2010 and 2015
CONCLUSION
Notwithstanding the little attention given recently to malaria epidemiology, to understand the local epidemiology in population, time and space in a greatly heterogeneous territory is of vital importance for malaria prevention, control and elimination in the region of the Americas. The use of malaria stratification is a relevant tool and should be used as a key strategy to plan malaria programs more efficiently and effectively. These plans are set at the national level but with the flexibility to lower levels to articulate interventions based on their needs. Therefore, this study adds a value when assessing the ...
Source: PLOS Currents Outbreaks - March 27, 2018 Category: Epidemiology Authors: Tiago Canelas Source Type: research
Dynamics and heterogeneity of brain damage in multiple sclerosis
by Ekaterina Kotelnikova, Narsis A. Kiani, Elena Abad, Elena H. Martinez-Lapiscina, Magi Andorra, Irati Zubizarreta, Irene Pulido-Valdeolivas, Inna Pertsovskaya, Leonidas G. Alexopoulos, Tomas Olsson, Roland Martin, Friedemann Paul, Jesper Tegn ér, Jordi Garcia-Ojalvo, Pablo Villoslada
Multiple Sclerosis (MS) is an autoimmune disease driving inflammatory and degenerative processes that damage the central nervous system (CNS). However, it is not well understood how these events interact and evolve to evoke such a highly dynamic and heterogeneous disease. We established a hypothes is whereby the variability in the course o...
Source: PLoS Computational Biology - October 26, 2017 Category: Biology Authors: Ekaterina Kotelnikova Source Type: research
High-fidelity simulation: Who has the most impressive laboratory?
Authors: Raurell-Torredà M, Gómez-Ibañez R, Miembros grupo GRISCA (Grup Recerca en Simulació a Catalunya i Andorra)
PMID: 28457502 [PubMed - in process] (Source: Enfermeria Intensiva)
Source: Enfermeria Intensiva - May 3, 2017 Category: Nursing Tags: Enferm Intensiva Source Type: research
Pancreatic neuroendocrine tumors.
Authors: Varas Lorenzo M, Cugat Andorra E, Capdevila Castillón J
Abstract
From Editor: Our serie of 70 cases with pancreatic neuroendocrine tumors compared with 79 cases of serie Cienfuegos et al.
PMID: 28253729 [PubMed - as supplied by publisher] (Source: Revista Espanola de Enfermedades Digestivas)
Source: Revista Espanola de Enfermedades Digestivas - March 4, 2017 Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
Structural networks involved in attention and executive functions in multiple sclerosis
In conclusion, structural brain connectivity is disturbed in MS due to widespread impairment of WM connections and gray matter structures. The increased edge connectivity suggests the presence of reorganization mechanisms at the structural level. Importantly, attention and executive performance relates to frontoparietal networks, deep gray nuclei and insula. These results support the relevance of network integrity to maintain optimal cognitive skills. (Source: NeuroImage: Clinical)
Source: NeuroImage: Clinical - December 4, 2016 Category: Radiology Source Type: research
Short-term predictive capacity of two different triage systems in patients with acute heart failure: TRICA-EAHFE study
Conclusion: The prediction of the outcome of patients with AHF determined with the MAT/SET or MTS showed scarce differences between the two systems, and their discriminative capacity does not seem to be clinically relevant. (Source: European Journal of Emergency Medicine)
Source: European Journal of Emergency Medicine - October 20, 2016 Category: Emergency Medicine Tags: Original Articles Source Type: research
[Sociodemographic and mental health risk factors: Global and local conditions according to the Survey results "mental health in the general population" in 18 international locations].
CONCLUSIONS: The impact of sociodemographic risk factors on mental health is confirmed regardless of World region. However, the implementation of action plans for the prevention of mental disorders requires a detailed understanding of people's needs in terms of the disorder's prevalence, nature and strength of risk factors, at regional and local levels. This observation provides incentives to develop this research axis in world francophone and Latin speaking areas. These epidemiological results can be refined thanks to the data collected in the MHGP surveys about each mental disorder and comorbid conditions, the recourse o...
Source: L Encephale - September 26, 2016 Category: Psychiatry Tags: Encephale Source Type: research
[Correspondence] Phenytoin for neuroprotection
Rhian Raftopoulos and colleagues1 reported that, compared with placebo, patients allocated to phenytoin treatment displayed a 30% reduction in thinning of the retinal nerve fibre layer (RNFL) evaluated with optical coherence tomography at 6 months in eyes with acute optic neuritis relative to baseline values of unaffected eyes. The study has methodological issues as discussed in the Comment,2 but here we raise the relevant question of whether the issue is an absence of demonstrated clinical benefit or of appropriate outcomes to measure thisbenefit. (Source: Lancet Neurology)
Source: Lancet Neurology - July 12, 2016 Category: Neurology Authors: Elena H Martinez-Lapiscina, Magi Andorra, Bernardo Sanchez-Dalmau, Pablo Villoslada Tags: Correspondence Source Type: research
