Autologous Falciform Ligament Graft for Vascular Reconstruction in Pancreatic Cancer Surgery

Publication date: Available online 10 December 2018Source: Cirugía Española (English Edition)Author(s): María Galofré-Recasens, Eric Herrero Fonollosa, Judith Camps Lasa, María Isabel García-Domingo, Esteban Cugat Andorrà
Source: Cirugia Espanola - Category: Surgery Source Type: research

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Authors: Capula M, Mantini G, Funel N, Giovannetti E Abstract Introduction. Most pancreatic cancer patients are diagnosed at advanced-stages and first-line regimens (FOLFIRINOX and gemcitabine/nab-paclitaxel) provide limited survival advantage and are associated with considerable toxicities. In this grim scenario, novel treatments and biomarkers are warranted.Areas covered. MicroRNAs (miRNAs) emerged as biomarkers for cancer prognosis and chemoresistance and blood-based miRNAs are being evaluated as indicators of therapeutic activity. Moreover, aberrant metabolism, such as aerobic glycolysis, has been correlated to...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
Authors: Kim DU PMID: 31724388 [PubMed - in process]
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
Publication date: Available online 14 November 2019Source: Acta Pharmaceutica Sinica BAuthor(s): Puvanesswaray Ramakrishnan, Wei Mee Loh, Subash C.B. Gopinath, Srinivasa Reddy Bonam, Ismail M. Fareez, Rhanye Mac Guad, Maw Shin Sim, Yuan Seng WuAbstractActivated pancreatic stellate cells (PSCs) have been widely accepted as a key precursor of excessive pancreatic fibrosis, which is a crucial hallmark of chronic pancreatitis (CP) and its formidable associated disease, pancreatic cancer (PC). Hence, anti-fibrotic therapy has been identified as a novel therapeutic strategy for treating CP and PC by targeting PSCs. Most of the a...
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Publication date: 14 November 2019Source: Cell, Volume 179, Issue 5Author(s): Avnish Kapoor, Wantong Yao, Haoqiang Ying, Sujun Hua, Alison Liewen, Qiuyun Wang, Yi Zhong, Chang-Jiun Wu, Anguraj Sadanandam, Baoli Hu, Qing Chang, Gerald C. Chu, Ramsey Al-Khalil, Shan Jiang, Hongai Xia, Eliot Fletcher-Sananikone, Carol Lim, Gillian I. Horwitz, Andrea Viale, Piergiorgio Pettazzoni
Source: Cell - Category: Cytology Source Type: research
Condition:   Pancreatic Ductal Adenocarcinoma Intervention:   Device: EUSRA electrode needle connected to a radiofrequency generator (VIVA RF generator; STARmed, Seoul, S. Korea) Sponsor:   Campus Bio-Medico University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Diabetes Mellitus;   Diabetes;   Diabetes Mellitus, Type 2;   Diabetes type2;   Cancer of Pancreas;   Pancreas Neoplasm;   Pancreas Adenocarcinoma;   Pancreatic Cancer Intervention:   Sponsors:   University of Pecs;   Hungarian Pancreatic Study Group (HPSG) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
Public awareness needs to increase to make sure the disease is picked up early and curb rise in cases, says Oral Health Foundation Related items fromOnMedica NHS must improve access to screening to save lives Third of emergency cancer presenters never saw GP Smartphone apps miss a third of melanomas Public urged to know what pancreatic cancer symptoms to look out for Parents urged to take toddlers for dental check
Source: OnMedica Latest News - Category: UK Health Source Type: news
THURSDAY, Nov. 14, 2019 -- Global burdens of colorectal cancer, pancreatic cancer, inflammatory bowel disease (IBD), and stomach cancer increased from 1990 to 2017, according to four studies published online Oct. 21 in The Lancet Gastroenterology...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
This study aimed to derive different fractions from the saponin-enriched extract of H. hirsuta stem using RP-HPLC and examine the in vitro anti-pancreatic cancer activity of the derived fractions (F0-F5). With the exception of F0, the five fractions (F1-F5) possessed strong inhibitory activity against PC cells at IC50 values of 3.11-17.12 μg/mL. The flow cytometry assays revealed the active fractions caused cell cycle arrest at S phase and promoted apoptosis in MIAPaCa-2 PC cells. The LC/MS analysis revealed that the isolated fractions contained bioactive compounds, such as caffeic acid, rosmarinic acid, sagerinic acid,...
Source: Molecular Biology Reports - Category: Molecular Biology Authors: Tags: Mol Biol Rep Source Type: research
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