Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may ...
Source: Presse Medicale - March 22, 2023 Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research

Efficacy of oral amantadine among patients hospitalised with COVID-19: A randomised, double-blind, placebo-controlled, multicentre study
Respir Med. 2023 Mar 15:107198. doi: 10.1016/j.rmed.2023.107198. Online ahead of print.ABSTRACTBACKGROUND: Amantadine has been proposed as a treatment for COVID-19 because it shows anti-SARS-CoV-2 activity in vitro. However, to date, no controlled study has assessed the safety and efficacy of amantadine in COVID-19.RESEARCH QUESTION: Whether amantadine is effective and safe among patients with different COVID-19 severity classifications.STUDY DESIGN: and Methods: This was multi-centre, randomised, placebo-controlled study.Patients with oxygen saturation ≤94% and no need for high-flow oxygen or ventilatory support were ra...
Source: Respiratory Care - March 17, 2023 Category: Respiratory Medicine Authors: Adam Barczyk Ma łgorzata Czajkowska-Malinowska Ma łgorzata Farnik Marek Barczyk Łukasz Boda Szczepan Cofta Jan Du ława Maciej Dyrbu ś Rafa ł Harat Maciej Huk Sylwia Kotecka Artur Nahorecki Jacek Nasi łowski Wojciech Naumnik Grzegorz Przybylski Moni Source Type: research

Efficacy of oral amantadine among patients hospitalised with COVID-19: A randomised, double-blind, placebo-controlled, multicentre study
Adding amantadine to standard care in patients hospitalised with COVID-19 did not increase the likelihood of recovery. (Source: Respiratory Medicine)
Source: Respiratory Medicine - March 14, 2023 Category: Respiratory Medicine Authors: Adam Barczyk, Ma łgorzata Czajkowska-Malinowska, Małgorzata Farnik, Marek Barczyk, Łukasz Boda, Szczepan Cofta, Jan Duława, Maciej Dyrbuś, Rafał Harat, Maciej Huk, Sylwia Kotecka, Artur Nahorecki, Jacek Nasiłowski, Wojciech Naumnik, Grzegorz Przyby Tags: Original Research Source Type: research