Optimising recovery of consciousness after coma. From bench to bedside and vice versa
DISCUSSION: Personalised sensory stimulation, median nerve stimulation, transcranial direct current stimulation (tDCS), amantadine and zolpidem all have favourable risk-benefit ratios and are easy to implement in clinical practice. These treatments should be proposed to every patient with chronic DoC. Comprehensive patient management should also include regular lifting, pain assessment and treatment, attempts to restore sleep and circadian rhythms, implementation of rest periods, comfort and nursing care, and a rehabilitation program with a multi-disciplinary team with expertise in this field. More invasive treatments may cause adverse effects and require further investigation to confirm preliminary, encouraging results and to better define responders' intervention parameters. Scientific studies are essential and given the severity of the disability and handicap that results from DoC, research in this area should aim to develop new therapeutic approaches.PMID:36948412 | DOI:10.1016/j.lpm.2023.104165
Source: Presse Medicale - Category: General Medicine Authors: Jacques Luaut é Maude Beaudoin-Gobert Source Type: research
More News: Amantadine | Ambien | Chronic Pain | Disability | General Medicine | Nurses | Nursing | Pain | Pain Management | Rehabilitation | Sleep Disorders | Sleep Medicine | Study | Symmetrel