Neurological adverse events of mitotane in adrenocortical carcinoma: results of a pilot study
ConclusionThe results of our study highlighted the presence of neurophysiological and neuropsychological abnormalities associated with mitotane values above 18 mg/L. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 14, 2023 Category: Cancer & Oncology Source Type: research
SLC17A9 expression levels in a pan ‑cancer panel and validation of the role of SLC17A9 as a novel prognostic biomarker for osteosarcoma
Oncol Lett. 2023 Jul 20;26(3):383. doi: 10.3892/ol.2023.13969. eCollection 2023 Sep.ABSTRACTPrevious studies have demonstrated the involvement of the solute carrier family 17 member 9 (SLC17A9) in certain types of cancer; however, the precise role of SLC17A9 is not well defined. In the present study, a comprehensive analysis was performed to determine the involvement of SLC17A9 in a pan-cancer panel. First, data on SLC17A9 expression levels from publicly available databases were obtained to determine SLC17A9 expression profiles in various types of cancer. Next, the involvement of SLC17A9 in the prognosis of patients, stemn...
Source: Oncology Letters - August 10, 2023 Category: Cancer & Oncology Authors: Junqing Li Feiran Wu Li Su Huimin Zhu Jie Yao Meng Zhang Source Type: research
Elucidating the clinical and immunological value of m6A regulator-mediated methylation modification patterns in adrenocortical carcinoma
Oncol Res. 2023 Jul 21;31(5):819-831. doi: 10.32604/or.2023.029414. eCollection 2023.ABSTRACTN6-methyladenosine methylation (m6A) is a common type of epigenetic alteration that prominently affects the prognosis of tumor patients. However, it is unknown how the m6A regulator affects the tumor microenvironment (TME) cell infiltration in adrenocortical carcinoma (ACC) and how it affects the prognosis of ACC patients yet. The m6A alteration patterns of 112 ACC patients were evaluated, furthermore, the association with immune infiltration cell features was investigated. The unsupervised clustering method was applied to typify t...
Source: Oncology Research - August 7, 2023 Category: Cancer & Oncology Authors: Wenhao Xu Haoming Li Yasir Hameed Mostafa A Abdel-Maksoud Saeedah Musaed Almutairi Ayman Mubarak Mohammed Aufy Wael Alturaiki Abdulaziz J Alshalani Ayman M Mahmoud Chen Li Source Type: research
