Mitotane Not Needed With Low- to Intermediate-Risk Adrenocortical Carcinoma
TUESDAY, Sept. 5, 2023 -- Mitotane does not show a significant improvement in the relapse rate and is associated with adverse events in patients with adrenocortical carcinoma considered to be at low-to-intermediate risk for recurrence, according to... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 5, 2023 Category: Pharmaceuticals Source Type: news
Janssen to Highlight Robust Solid Tumor Portfolio and Pipeline at 2021 ASCO GU
February 2, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it will highlight the depth of its solid tumor portfolio at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium with 12 data presentations, including three company-sponsored oral presentations from the ERLEADA® (apalutamide) clinical development program. The virtual meeting will take place February 11-13, 2021. “We are committed to the development of innovative therapies for patients with genitourinary cancers for whom there remains a high unmet need,” said Craig Tendler, M...
Source: Johnson and Johnson - February 2, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news
Oncotarget: GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma
(Impact Journals LLC) The cover for issue 36 of Oncotarget features Figure 7, 'Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model,' by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 8, 2020 Category: Cancer & Oncology Source Type: news
Leptomeningeal Metastasis from Adrenocortical Carcinoma Leptomeningeal Metastasis from Adrenocortical Carcinoma
Here the authors discuss a case of adrenocortical carcinoma with metastatic spread that rapidly progressed.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 22, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Adrenocortical Carcinoma in Children
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 8, 2017 Category: General Medicine Source Type: news
Adrenocortical Carcinoma
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 14, 2017 Category: General Medicine Source Type: news
[Research Article] Dosage-dependent regulation of VAV2 expression by Steroidogenic Factor-1 drives adrenocortical carcinoma cell invasion
Inhibiting the guanine nucleotide exchange factor VAV2 may prevent metastatic progression of adrenocortical carcinoma. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - March 7, 2017 Category: Science Authors: Carmen Ruggiero, Mabrouka Doghman-Bouguerra, Silviu Sbiera, Iuliu Sbiera, Maddy Parsons, Bruno Ragazzon, Aur é lie Morin, Estelle Robidel, Judith Favier, J é r ô me Bertherat, Martin Fassnacht, Enzo Lalli Source Type: news
St. Jude Children's Research Hospital research being presented at ASCO Annual Meeting
(St. Jude Children's Research Hospital) St. Jude Children's Research Hospital research related to survivorship and the pediatric solid tumors neuroblastoma, adrenocortical carcinoma and nasopharyngeal carcinoma will be presented at the 2016 American Society of Clinical Oncology Annual Meeting. The five-day event begins June 3 in Chicago. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 3, 2016 Category: Cancer & Oncology Source Type: news
Resection of recurrence shows survival benefit for adrenocortical carcinoma
BALTIMORE – Patients who have recurrent adrenocortical carcinoma appear to have one option to increase their survival: surgery that includes complete tumor resection – but it may a viable path only... (Source: Clinical Endocrinology News)
Source: Clinical Endocrinology News - May 25, 2016 Category: Endocrinology Source Type: news
Study shows possible 'key' to improved therapy for adrenocortical carcinoma
A study by researchers in Texas and published in Cancer Cell has revealed significant new findings about adrenocortical carcinoma.
EurekAlert (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 10, 2016 Category: Endocrinology Source Type: news
Study shows possible 'key' to improved therapy for adrenocortical carcinoma
Significant new findings about adrenocortical carcinoma, a rare cancer with an often poor prognosis, have been revealed by a new study comprised of 39 international institutions. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 9, 2016 Category: Science Source Type: news
TGen and international team find new avenues of precision medicine for treating cancer
(The Translational Genomics Research Institute) An international team of scientists, including those at the Translational Genomic Research Institute, have discovered new avenues of potential treatments for a rare and deadly cancer known as adrenocortical carcinoma (ACC). In a study published today in the scientific journal Cancer Cell, researchers conducted an extensive genomic profile of ACC, a cancer of the adrenal glands, located above the kidneys. Current treatment options for ACC have not changed in decades and are not curative. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 9, 2016 Category: Cancer & Oncology Source Type: news
Study shows possible 'key' to improved therapy for adrenocortical carcinoma
(University of Texas M. D. Anderson Cancer Center) A study comprised of 39 international institutions revealed significant new findings about adrenocortical carcinoma, a rare cancer with an often poor prognosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 9, 2016 Category: Global & Universal Source Type: news
TERT promoter mutations in adrenal tumours
The telomerase reverse transcriptase gene (TERT) is essential for telomere stabilization and cell immortalization. A role for TERT promoter mutations C228T and C250T has been demonstrated in aggressive human cancer. The underlying mechanisms of telomerase activation is not known in adrenal tumors. Liu and colleagues assessed C228T and C250T TERT mutations, finding that TERT promoter mutation C228T is a recurrent event associated with adrenocortical carcinoma, but rarely occurs in paraganglioma or pheochromocytoma. The involvement of the TERT gene in adrenocortical carcinoma is a new finding.
Read the full article at Liu e...
Source: Society for Endocrinology - June 26, 2014 Category: Endocrinology Source Type: news
Monday's pick of the day
The first day of BES 2014 kicks off with a host of varied, topical symposia, clinical management workshops, and an applied physiology workshop. Look out for our first education workshop at 15.45, room 3B Teaching and learning in endocrinology.
Make sure you catch Peter Taylor’s talk at 13.45, room 1A on the link between low thyroid hormone levels and a genetic variant, and the development of low IQ. The work is covered today in news stories in the Telegraph, BBC and Mail online. The abstract is the Clinical Endocrinology Trust top-scoring clinical abstract.
We are grateful to our industry supporters who have en...
Source: Society for Endocrinology - March 23, 2014 Category: Endocrinology Source Type: news
