Bilateral Adult-Onset Orbital Xanthogranuloma: A Case Report
In this report, we present a compelling case of bilateral periorbital AOX. Initially, the patient received a diagnosis of necrotizing xanthogranuloma (NBX) and underwent treatment with dapsone, which yielded a poor response. Subsequently, through repeated biopsy, immunoprotein electrophoresis, and high-throughput sequencing, the diagnosis was revised to AOX. Subsequently, the patient's treatment was modified to include oral hormone therapy, and no further progression of the periorbital plaque was observed. Notably, the patient's sister was diagnosed with xanthelasma palpebrarum (XP), suggesting a potential genetic associat...
Source: Clinical, Cosmetic and Investigational Dermatology - December 19, 2023 Category: Dermatology Authors: Yue Chen Aili Gao Xin Tian Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
Unusual direct immunofluorescence (DIF) pattern in pemphigus herpetiformis- A case report
Indian J Pathol Microbiol. 2023 Oct-Dec;66(4):852-854. doi: 10.4103/IJPM.IJPM_879_20.ABSTRACTPemphigus herpetiformis (PH) is an autoimmune intraepithelial bullous skin disorder. A 61-year-old female presented with history of multiple pruritic erosions, ulcers all over body, and diffuse loss of hair over scalp. Oral and genital mucosas were uninvolved. Subcorneal separation with suprapapillary thinning of epidermis, neutrophilic spongiosis, and elongation of rete ridges were seen on histopathology. Direct immunofluorescence (DIF) revealed IgG deposits in intercellular zone in fish net like pattern and focal linear IgA depos...
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Rawat Kavita Azad Sheenam Bahal Neelima Bisht S Jitender Source Type: research
