Erythema elevatum diutinum in a patient with rheumatoid arthritis
We report a 65-year-old woman with painful and itchy lesions on her elbows, hands, knees, and foot for a year. Histopathologic examination confirmed the diagnosis of erythema elevatum diutinum and treatment with dapsone produced significant clinical improvement within few weeks. Erythema elevatum diutinum is a rare disease that should be considered in patients with violaceous nodular plaques located over the extensor regions of the limbs. Knowledge of this unusual pathology and its association helps to avoid misdiagnosis and late treatment.PMID:38478644 | DOI:10.5070/D329562408 (Source: Dermatol Online J)
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Maraya Semblano Bittencourt Tally Serruya Luana De Oliveira Loureiro Aline Dias Coelho De Souza Camilla Correa Neri Ana Thais Machado Moutinho Caren Dos Santos Lima Source Type: research
Linear IgA bullous dermatosis associated with immunotherapy
We present the case of a 67-year-old woman with metastatic ovarian cancer receiving anti-PD1 and anti-CTLA4 with new onset pruritic tense bullae to the trunk, hands, elbows (in annular distribution) that occurred after immunotherapy. Skin biopsy showed subepidermal blister with abundant neutrophils on H&E histology, and linear IgA staining at the basement membrane on direct immunofluorescence consistent with the diagnosis of LABD. The condition did not improve on initial prednisone taper, but blisters rapidly resolved a few days after initiation of dapsone therapy. We favor that our patient's LABD is secondary to h...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Bahar Momin Tue F Nguyen Daniel Glade Alison Messer Source Type: research
Red crusty plaques in a young man
Dermatol Online J. 2023 Oct 15;29(5). doi: 10.5070/D329562411.ABSTRACTPemphigus foliaceus is a superficial blistering disorder characterized by erosions and scaling in a seborrheic distribution. The condition typically occurs in healthy individuals but issues arise from delayed diagnosis. Many cases remain undiagnosed or misdiagnosed due to the lack of awareness of the condition. With use of common diagnostic tools, pemphigus foliaceus can be easily identified and monitored. Histological analysis exhibits "chicken wire" patterning along keratinocytes in the upper epidermis, whereas immunofluorescence study displays subcorn...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Mishma Farsi Cassandra M Johnson Kelly Segars Jonathan Rhim Source Type: research
Erythema elevatum diutinum in a patient with rheumatoid arthritis
We report a 65-year-old woman with painful and itchy lesions on her elbows, hands, knees, and foot for a year. Histopathologic examination confirmed the diagnosis of erythema elevatum diutinum and treatment with dapsone produced significant clinical improvement within few weeks. Erythema elevatum diutinum is a rare disease that should be considered in patients with violaceous nodular plaques located over the extensor regions of the limbs. Knowledge of this unusual pathology and its association helps to avoid misdiagnosis and late treatment.PMID:38478644 | DOI:10.5070/D329562408 (Source: Dermatol Online J)
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Maraya Semblano Bittencourt Tally Serruya Luana De Oliveira Loureiro Aline Dias Coelho De Souza Camilla Correa Neri Ana Thais Machado Moutinho Caren Dos Santos Lima Source Type: research
Linear IgA bullous dermatosis associated with immunotherapy
We present the case of a 67-year-old woman with metastatic ovarian cancer receiving anti-PD1 and anti-CTLA4 with new onset pruritic tense bullae to the trunk, hands, elbows (in annular distribution) that occurred after immunotherapy. Skin biopsy showed subepidermal blister with abundant neutrophils on H&E histology, and linear IgA staining at the basement membrane on direct immunofluorescence consistent with the diagnosis of LABD. The condition did not improve on initial prednisone taper, but blisters rapidly resolved a few days after initiation of dapsone therapy. We favor that our patient's LABD is secondary to h...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Bahar Momin Tue F Nguyen Daniel Glade Alison Messer Source Type: research
Red crusty plaques in a young man
Dermatol Online J. 2023 Oct 15;29(5). doi: 10.5070/D329562411.ABSTRACTPemphigus foliaceus is a superficial blistering disorder characterized by erosions and scaling in a seborrheic distribution. The condition typically occurs in healthy individuals but issues arise from delayed diagnosis. Many cases remain undiagnosed or misdiagnosed due to the lack of awareness of the condition. With use of common diagnostic tools, pemphigus foliaceus can be easily identified and monitored. Histological analysis exhibits "chicken wire" patterning along keratinocytes in the upper epidermis, whereas immunofluorescence study displays subcorn...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Mishma Farsi Cassandra M Johnson Kelly Segars Jonathan Rhim Source Type: research
Erythema elevatum diutinum in a patient with rheumatoid arthritis
We report a 65-year-old woman with painful and itchy lesions on her elbows, hands, knees, and foot for a year. Histopathologic examination confirmed the diagnosis of erythema elevatum diutinum and treatment with dapsone produced significant clinical improvement within few weeks. Erythema elevatum diutinum is a rare disease that should be considered in patients with violaceous nodular plaques located over the extensor regions of the limbs. Knowledge of this unusual pathology and its association helps to avoid misdiagnosis and late treatment.PMID:38478644 | DOI:10.5070/D329562408 (Source: Dermatol Online J)
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Maraya Semblano Bittencourt Tally Serruya Luana De Oliveira Loureiro Aline Dias Coelho De Souza Camilla Correa Neri Ana Thais Machado Moutinho Caren Dos Santos Lima Source Type: research
Linear IgA bullous dermatosis associated with immunotherapy
We present the case of a 67-year-old woman with metastatic ovarian cancer receiving anti-PD1 and anti-CTLA4 with new onset pruritic tense bullae to the trunk, hands, elbows (in annular distribution) that occurred after immunotherapy. Skin biopsy showed subepidermal blister with abundant neutrophils on H&E histology, and linear IgA staining at the basement membrane on direct immunofluorescence consistent with the diagnosis of LABD. The condition did not improve on initial prednisone taper, but blisters rapidly resolved a few days after initiation of dapsone therapy. We favor that our patient's LABD is secondary to h...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Bahar Momin Tue F Nguyen Daniel Glade Alison Messer Source Type: research
Red crusty plaques in a young man
Dermatol Online J. 2023 Oct 15;29(5). doi: 10.5070/D329562411.ABSTRACTPemphigus foliaceus is a superficial blistering disorder characterized by erosions and scaling in a seborrheic distribution. The condition typically occurs in healthy individuals but issues arise from delayed diagnosis. Many cases remain undiagnosed or misdiagnosed due to the lack of awareness of the condition. With use of common diagnostic tools, pemphigus foliaceus can be easily identified and monitored. Histological analysis exhibits "chicken wire" patterning along keratinocytes in the upper epidermis, whereas immunofluorescence study displays subcorn...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Mishma Farsi Cassandra M Johnson Kelly Segars Jonathan Rhim Source Type: research
Erythema elevatum diutinum in a patient with rheumatoid arthritis
We report a 65-year-old woman with painful and itchy lesions on her elbows, hands, knees, and foot for a year. Histopathologic examination confirmed the diagnosis of erythema elevatum diutinum and treatment with dapsone produced significant clinical improvement within few weeks. Erythema elevatum diutinum is a rare disease that should be considered in patients with violaceous nodular plaques located over the extensor regions of the limbs. Knowledge of this unusual pathology and its association helps to avoid misdiagnosis and late treatment.PMID:38478644 | DOI:10.5070/D329562408 (Source: Dermatol Online J)
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Maraya Semblano Bittencourt Tally Serruya Luana De Oliveira Loureiro Aline Dias Coelho De Souza Camilla Correa Neri Ana Thais Machado Moutinho Caren Dos Santos Lima Source Type: research
Linear IgA bullous dermatosis associated with immunotherapy
We present the case of a 67-year-old woman with metastatic ovarian cancer receiving anti-PD1 and anti-CTLA4 with new onset pruritic tense bullae to the trunk, hands, elbows (in annular distribution) that occurred after immunotherapy. Skin biopsy showed subepidermal blister with abundant neutrophils on H&E histology, and linear IgA staining at the basement membrane on direct immunofluorescence consistent with the diagnosis of LABD. The condition did not improve on initial prednisone taper, but blisters rapidly resolved a few days after initiation of dapsone therapy. We favor that our patient's LABD is secondary to h...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Bahar Momin Tue F Nguyen Daniel Glade Alison Messer Source Type: research
Red crusty plaques in a young man
Dermatol Online J. 2023 Oct 15;29(5). doi: 10.5070/D329562411.ABSTRACTPemphigus foliaceus is a superficial blistering disorder characterized by erosions and scaling in a seborrheic distribution. The condition typically occurs in healthy individuals but issues arise from delayed diagnosis. Many cases remain undiagnosed or misdiagnosed due to the lack of awareness of the condition. With use of common diagnostic tools, pemphigus foliaceus can be easily identified and monitored. Histological analysis exhibits "chicken wire" patterning along keratinocytes in the upper epidermis, whereas immunofluorescence study displays subcorn...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Mishma Farsi Cassandra M Johnson Kelly Segars Jonathan Rhim Source Type: research
Erythema elevatum diutinum in a patient with rheumatoid arthritis
We report a 65-year-old woman with painful and itchy lesions on her elbows, hands, knees, and foot for a year. Histopathologic examination confirmed the diagnosis of erythema elevatum diutinum and treatment with dapsone produced significant clinical improvement within few weeks. Erythema elevatum diutinum is a rare disease that should be considered in patients with violaceous nodular plaques located over the extensor regions of the limbs. Knowledge of this unusual pathology and its association helps to avoid misdiagnosis and late treatment.PMID:38478644 | DOI:10.5070/D329562408 (Source: Dermatol Online J)
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Maraya Semblano Bittencourt Tally Serruya Luana De Oliveira Loureiro Aline Dias Coelho De Souza Camilla Correa Neri Ana Thais Machado Moutinho Caren Dos Santos Lima Source Type: research
Linear IgA bullous dermatosis associated with immunotherapy
We present the case of a 67-year-old woman with metastatic ovarian cancer receiving anti-PD1 and anti-CTLA4 with new onset pruritic tense bullae to the trunk, hands, elbows (in annular distribution) that occurred after immunotherapy. Skin biopsy showed subepidermal blister with abundant neutrophils on H&E histology, and linear IgA staining at the basement membrane on direct immunofluorescence consistent with the diagnosis of LABD. The condition did not improve on initial prednisone taper, but blisters rapidly resolved a few days after initiation of dapsone therapy. We favor that our patient's LABD is secondary to h...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Bahar Momin Tue F Nguyen Daniel Glade Alison Messer Source Type: research
Red crusty plaques in a young man
Dermatol Online J. 2023 Oct 15;29(5). doi: 10.5070/D329562411.ABSTRACTPemphigus foliaceus is a superficial blistering disorder characterized by erosions and scaling in a seborrheic distribution. The condition typically occurs in healthy individuals but issues arise from delayed diagnosis. Many cases remain undiagnosed or misdiagnosed due to the lack of awareness of the condition. With use of common diagnostic tools, pemphigus foliaceus can be easily identified and monitored. Histological analysis exhibits "chicken wire" patterning along keratinocytes in the upper epidermis, whereas immunofluorescence study displays subcorn...
Source: Dermatol Online J - March 13, 2024 Category: Dermatology Authors: Mishma Farsi Cassandra M Johnson Kelly Segars Jonathan Rhim Source Type: research
