Poster abstracts
The objective of the current analysis is to report pooled safety data from the two pivotal phase 3 studies (AMPOWER and AMP001). (Source: Contraception)
Source: Contraception - September 7, 2021 Category: OBGYN Authors: T Lee, K Culwell, C Dart, B Howard Source Type: research
Efficacy and safety of prolonged-release hyaluronic acid derivative vaginal application in the postpartum period: a prospective randomised clinical trial
CONCLUSIONS: The results of our study demonstrated that hyaluronic acid derivative vaginal gel (Hydeal-D) was able to improve sexual function of puerperal women in the short-term treatment.KEY MESSAGEIn the puerperium, the hypoestrogenic state induced by delivery and subsequently sustained by lactation may lead to vaginal dryness, burning, and itching sensation, contributing to the onset of sexual dysfunction.Hydeal-D is a prolonged-release hyaluronic acid derivative characterised by elevated resistance to enzymatic breakdown. During puerperium, its local application may improve the vaginal microenvironment by ensuring a b...
Source: Annals of Medicine - September 3, 2021 Category: Internal Medicine Authors: Claudio Gustavino Paolo Sala Nadia Cusini Brunella Gravina Cecilia Ronzini Diletta Marcolin Valerio Gaetano Vellone Michele Paudice Rossella Nappi Sergio Costantini Simone Ferrero Fabio Barra Source Type: research
SIDE EFFECTS BY FREQUENCY OF USE WITH EVO100 VAGINAL GEL: Results FROM THE PHASE 2B/3 AMPREVENCE TRIAL
The objective of the current analysis is to report on side effects by frequency of study drug use. (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2021 Category: Reproduction Medicine Authors: Ronald Z. Surowitz, Kelly R. Culwell, Scott G. Mollan, Brandon Howard Source Type: research
TIMING OF ON-STUDY PREGNANCIES WITH A VAGINAL pH MODULATOR IN THE PHASE 3 AMPOWER TRIAL
The objective of this post-hoc analysis was to analyze timing of on-study pregnancies. (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2021 Category: Reproduction Medicine Authors: B. Todd Chappell, Kelly R. Culwell, Clint Dart, Brandon Howard Source Type: research
Phexxi —A Nonhormonal Contraceptive Gel
This Medical Letter review summarizes the use of Phexxi (Evofem), a nonhormonal vaginal gel containing lactic acid, citric acid, and potassium bitartrate, for prevention of pregnancy. (Source: JAMA)
Source: JAMA - August 24, 2021 Category: General Medicine Source Type: research
Chlorhexidine, clotrimazole, metronidazole and combination therapy in the treatment of vaginal infections
J Med Life. 2021 Mar-Apr;14(2):250-256. doi: 10.25122/jml-2019-0160.ABSTRACTThis was a clinical trial study that aimed to investigate the efficacy of vaginal chlorhexidine gel in the treatment of vulvovaginal candidiasis, bacterial vaginosis, and nonspecific vaginitis. The study population included patients who complained of vaginal discharge and presented to our University Gynecology Clinic. The data were analyzed using the Statistical Package for the Social Sciences (SPSS) software. The student t-test and Mann-Whitney U test were used to analyze the quantitative and ordinal data, respectively. In order to analyze the qua...
Source: Journal of Medicine and Life - June 9, 2021 Category: General Medicine Authors: Shahla Mirzaeei Maryam Zangeneh Firoozeh Veisi Somayeh Parsa Maryam Hematti Source Type: research
