IL-19 Regulates Atherosclerotic Plaque Progression via Lymphangiogenesis
CONCLUSION & SUMMARY: These data suggest that IL-19 increases lymphatic vessel formation, potentially allowing RCT to take place to decrease plaque burden in atherosclerosis. Further studies will confirm IL-19's mechanistic pathway in LECs. We will also determine RCT and inflammatory cell trafficking by intravital microscopy. These results have the potential to shift our understanding toward a positive view of the association between the lymphatic system and atherosclerosis.PMID:35554476 | DOI:10.1096/fasebj.2022.36.S1.R5435
Source: Atherosclerosis - Category: Cardiology Authors: Amanda Peluzzo Kyle Preston Tani Leigh Sheri Kelemen Michael Autieri Source Type: research
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