Comprehensive analysis of spliceosome genes and their mutants across 27 cancer types in 9070 patients: clinically relevant outcomes in the context of 3P medicine

ConclusionsThis study provided the first landscape of spliceosome changes across 27 cancer types in 9070 patients and revealed that spliceosome was related to tumor progression. Spliceosome may play important an important role in cancer biological processes. These findings are the important scientific data to demonstrate the common and specific changes of spliceosome genes across 27 cancer types, which is a valuable biomarker resource to under the common or specific molecular mechanisms among different cancer types and establish biomarkers and therapeutic targets for the common or specific management of different types of cancer patients to benefit the research and practice of 3P medicine in cancers.
Source: EPMA Journal - Category: International Medicine & Public Health Source Type: research