Elevated Lipoprotein(a) and Risk of Atrial  Fibrillation: An Observational and Mendelian Randomization Study

CONCLUSIONS: Our findings implicate Lp(a) as a potential causal mediator in the development of AF which show that the effects of Lp(a) extend across myocardial tissues. Ongoing clinical trials for Lp(a)-lowering therapies should evaluate effects on AF prevention.PMID:35450575 | DOI:10.1016/j.jacc.2022.02.018

Source: Atherosclerosis - April 22, 2022 Category: Cardiology Authors: Pedrum Mohammadi-Shemirani Michael Chong Sukrit Narula Nicolas Perrot David Conen Jason D Roberts S ébastien Thériault Yohan Boss é Matthew B Lanktree Marie Pigeyre Guillaume Par é Source Type: research