Cardiac Remodeling in Hypertension: Clinical Impact on Brain, Heart, and Kidney Function

Horm Metab Res DOI: 10.1055/a-1793-6134Hypertension is the most common causative factor of cardiac remodeling, which, in turn, has been associated with changes in brain and kidney function. Currently, the role of blood biomarkers as indices of cardiac remodeling remains unclear. In contrast, cardiac imaging, including echocardiography and cardiovascular magnetic resonance (CMR), has been a valuable noninvasive tool to assess cardiac remodeling. Cardiac remodeling during the course of systemic hypertension is not the sole effect of the latter. “Remodeling” of other vital organs, such as brain and kidney, also takes place. Therefore, it will be more accurate if we discuss about “hypertensive remodeling” involving the heart, the brain, and the kidneys, rather than isolated cardiac remodeling. This supports the idea of their simultaneous assessment to identify the early, silent lesions of total “hypertensive remodeling”. In this context, magnetic resonance imaging is the ideal modality to provide useful information about these organs in a noninvasive fashion and without radiation. For this purpose, we propose a combined protocol to employ MRI in the simultaneous assessment of the heart, brain and kidneys. This protocol should include all necessary indices for the evaluation of “hypertensive remodeli...
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Tags: Review Source Type: research