Cardiac Remodeling in Hypertension: Clinical Impact on Brain, Heart, and Kidney Function
Horm Metab Res DOI: 10.1055/a-1793-6134Hypertension is the most common causative factor of cardiac remodeling, which, in
turn, has been associated with changes in brain and kidney function. Currently,
the role of blood biomarkers as indices of cardiac remodeling remains unclear.
In contrast, cardiac imaging, including echocardiography and cardiovascular
magnetic resonance (CMR), has been a valuable noninvasive tool to assess cardiac
remodeling. Cardiac remodeling during the course of systemic hypertension is not
the sole effect of the latter. “Remodeling” of other vital
organs, such as brain and kidney, also takes place. Therefore, it will be more
accurate if we discuss about “hypertensive remodeling” involving
the heart, the brain, and the kidneys, rather than isolated cardiac remodeling.
This supports the idea of their simultaneous assessment to identify the early,
silent lesions of total “hypertensive remodeling”. In this
context, magnetic resonance imaging is the ideal modality to provide useful
information about these organs in a noninvasive fashion and without radiation.
For this purpose, we propose a combined protocol to employ MRI in the
simultaneous assessment of the heart, brain and kidneys. This protocol should
include all necessary indices for the evaluation of “hypertensive
remodeli...
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Mavrogeni, Sophie Piaditis, George Bacopoulou, Flora Chrousos, George P. Tags: Review Source Type: research
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