Cryptococcal Meningitis Reported With Fingolimod Treatment: Case Series

Discussion
The causal relationship between fingolimod treatment and CM is not yet fully understood. The CM mortality rate in fingolimod-treated patients is similar to that reported in HIV-negative patients. Vigilance for signs and symptoms of CM in patients receiving fingolimod, particularly the new onset of headaches and altered mental status, is essential. Early diagnosis and treatment are critical to reducing CM-associated mortality.

Source: Neurology Neuroimmunology and Neuroinflammation - March 22, 2022 Category: Neurology Authors: Del Poeta, M., Ward, B. J., Greenberg, B., Hemmer, B., Cree, B. A. C., Komatireddy, S., Mishra, J., Sullivan, R., Kilaru, A., Moore, A., Hach, T., Berger, J. R. Tags: Autoimmune diseases, Fungal infections, Multiple sclerosis Research Article Source Type: research