Systematic Data Monitoring and Analysis of Cardiovascular Off-label Prescriptions in Pediatrics: Focus on Angiotensin-Converting Enzyme Inhibitors (ACE-I) and Beta Blockers
ConclusionOff-label in pediatrics is largely widespread in Europe and US and our results show it is also present in Italy. Molecules selected are usedoff-label for therapeutic areas such as oncologic, hematological and rare diseases. Results of pharmacovigilance suggests underreporting. The analysis carried out in this study could be an open track for a systematic monitoring activity and of interest for prescribers, pediatricians and other healthcare professionals during the clinical practice.
Source: High Blood Pressure and Cardiovascular Prevention - Category: Cardiology Source Type: research
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