IJERPH, Vol. 18, Pages 10012: Burden of Mortality from Asbestos-Related Diseases in Italy

IJERPH, Vol. 18, Pages 10012: Burden of Mortality from Asbestos-Related Diseases in Italy International Journal of Environmental Research and Public Health doi: 10.3390/ijerph181910012 Authors: Lucia Fazzo Alessandra Binazzi Daniela Ferrante Giada Minelli Dario Consonni Lisa Bauleo Caterina Bruno Marcella Bugani Marco De Santis Ivano Iavarone Corrado Magnani Elisa Romeo Amerigo Zona Mariano Alessi Pietro Comba Alessandro Marinaccio Asbestos is one of the major worldwide occupational carcinogens. The global burden of asbestos-related diseases (ARDs) was estimated around 231,000 cases/year. Italy was one of the main European asbestos producers until the 1992 ban. The WHO recommended national programs, including epidemiological surveillance, to eliminate ARDs. The present paper shows the estimate of the burden of mortality from ARDs in Italy, established for the first time. National standardized rates of mortality from mesothelioma and asbestosis and their temporal trends, based on the National Institute of Statistics database, were computed. Deaths from lung cancer attributable to asbestos exposure were estimated using population-based case-control studies. Asbestos-related lung and ovarian cancer deaths attributable to occupational exposure were estimated, considering the Italian occupational cohort studies. In the 2010–2016 period, 4400 deaths/year attributable to asbestos were estimated: 1515 from mesothelioma, 58 from asbestosis, ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research

Related Links:

Imagine a world in which physicians can confidently cure cancer. Two Bay Area life sciences companies are working together to make this vision a reality. Atara Biotherapeutics Inc., founded in 2012, is developing a pipeline of cell therapies to treat various types of cancer and autoimmune diseases. Bayer is licensing Atara’s cutting-edge cell therapies that t arget certain types of aggressive tumors including mesothelioma, pancreatic, ovarian and non-small-cell lung cancer. “With cancer therapies,…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Canada may soon become the first country to legally restrict the use of popular talc-based products, stemming from an extensive, recently completed human health assessment of the naturally occurring mineral. Health Canada, the governmental agency responsible for national health policy, issued an official advisory in April, concluding that loose talc products – such as body powder, baby powder and genital deodorants – can cause serious lung problems and ovarian cancer. The agency has proposed expanded restrictions on the use of talc in cosmetics, natural health products and nonprescription drugs that can b...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
The number of mesothelioma lawsuits filed in 2020 dropped significantly, while cases involving lung cancer continued to increase, according to a recent study reflecting the changing face of asbestos litigation. KCIC, a well-respected consulting firm in Washington, D.C., that manages asbestos product liabilities, released its industry report Thursday. Asbestos legal filings, covering both malignant and nonmalignant disease in the United States, dropped 11% from 2019 to 2020, from 4,137 to 3,685 cases, respectively. Most prominently, there was a 9% increase in asbestos-related lung cancer filings, but a 14% decrease...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
The U.S. Environmental Protection Agency released Part 1 of its Final Risk Evaluation for Asbestos, reaffirming preliminary findings from March that were roundly criticized for underestimating the dangers of exposure to this toxic mineral. Six ongoing use categories of asbestos were evaluated by the EPA, which found 16 conditions of use that presented unreasonable risk to human health through either occupational exposures or consumer uses. Part 1 of the evaluation, released in late December 2020, involved the chrysotile type of asbestos. Chrysotile is the only type of asbestos being imported, processed or distributed for u...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
CONCLUSION: Our findings unravel several un-explored avenues related to the role of TC2N in tumourigenesis of several cancers, suggesting TC2N as an important player and a potential candidate for tumour-therapy. PMID: 33247676 [PubMed - as supplied by publisher]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
While the incidence of malignant mesothelioma in the United States continued its gradual decline, the tendency to sue for damages drastically increased in recent years, according to a KCIC study. Lawsuits filed by those stricken with the deadly asbestos-related cancer increased 65.7% from 2007 to 2017. Meanwhile, the overall incidence rate of mesothelioma dropped 16.2% during the same period. KCIC, a well-regarded consulting firm in Washington, D.C., that manages asbestos product liabilities, published the study of mesothelioma and asbestos litigation last week. Study author Megan Shockley, senior manager at KCIC, was unav...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
The Science Advisory Committee on Chemicals found considerable failings and an underestimation of danger to the general public in a draft risk evaluation of asbestos submitted earlier this year by the U.S. Environmental Protection Agency. SACC, which serves as a scientific, peer-review mechanism for the EPA, released its recommendations last week in the ongoing governmental reevaluation of asbestos. This is the latest step in the amended Toxic Substances Control Act that requires the EPA to conduct evaluations on specific chemicals to determine whether they present unreasonable risk under conditions of use. The committee w...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
A mesothelioma clinical trial involving genetically modified T cells has opened to considerable acclaim, shrinking tumors in the first five patients who were treated. The phase I portion of the clinical trial is designed to define the safety profile and optimal dosage level of TC-210, a novel immunotherapy targeting mesothelin, a cell-surface protein often overexpressed in several cancers. While T cell modifications in the laboratory are proving safe and well tolerated, the initial signs of consistent efficacy became an early bonus in phase I. Four of the patients treated had mesothelioma. The fifth had ovarian cancer. All...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
ConclusionsRadiolabeled anti-mesothelin antibodies could be crucial as a treatment tool and for predicting the eligibility and the response of the patient to radioimmunotherapy through the study of the expression grade of mesothelin. They can be a relevant tool for pancreatic adenocarcinoma, lung cancer, human epidermoid carcinoma, ovarian cancer, malignant mesothelioma in which mesothelin is widely expressed.
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research
A recent rise in litigation linking cosmetic talc with mesothelioma and lung cancer will continue throughout 2020, despite companies abandoning the product in the hope of avoiding costly verdicts. The number of legal cases is expected to increase by 10% this year, building on an 11% rise in 2019, according to KCIC, a well-regarded consulting firm based in Washington, D.C., that manages asbestos product liabilities. “A new trend we have started to see is talc allegations showing up in traditional asbestos complaints,” said KCIC Vice President Michelle Potter during a recent webinar that looked at past litigation...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
More News: Asbestosis | Cancer | Cancer & Oncology | Databases & Libraries | Environmental Health | Epidemiology | Health Management | International Medicine & Public Health | Italy Health | Lung Cancer | Mesothelioma | Occupational Health | Ovarian Cancer | Ovaries | Statistics | Study