Natural and synthetic naphthoquinones as potential anti-infective agents

CONCLUSION: In this review, natural and synthetic naphthoquinone showed antiparasitic activity, in the most cases with improved results than current drugs currently used in clinical trials. A modification of their structure with different functional groups can enhance their biological effects, improve solubility, and reduce undesirable side effects. Therefore, naphthoquinones are important molecules in the development of new chemotherapeutic agents against parasitic diseases.PMID:34525920 | DOI:10.2174/1568026621666210915121348

Source: Current Topics in Medicinal Chemistry - September 16, 2021 Category: Chemistry Authors: Eyra Ortiz-P érez Karina V ázquez Gildardo Rivera Cristian O Salas J Jos é Zarate-Ramos Oleksandra S Trofymchuk Lucio Hernandez-Soberanis Juanita Deniss Perales-Flores Source Type: research