The Effect of Verapamil on TXNIP Gene Expression, GLP1R mRNA, FBS, HbA1c, and Lipid Profile in T2DM Patients Receiving Metformin and Sitagliptin

ConclusionVerapamil can lead to better control of T2DM by reducing TXNIP gene expression and increasing beta cell survival and, possibly, by other mechanisms.Clinical Trial RegistrationIRCT registration no.: IRCT20180417039339N1 (https://www.IRCT.ir).
Source: Diabetes Therapy - Category: Endocrinology Source Type: research