P –357 The risk factors for early pregnancy loss based on a logistic model following 13,977 infertile patients after in vitro fertilization

AbstractStudy questionWhat are the risk factors for early pregnancy loss (EPL) after in vitro fertilization-embryo transfer (IVF-ET)?Summary answerThe maternal age, gestational sac diameter, embryonic length, yolk sac diameter, heart rate of day 27 –29 and endometrium thickness on transfer day were risk factors. What is known already: The first routine ultrasound scan is commonly arranged on day 27–29 after IVF-ET in most reproductive centers in China to determine the location and viability of the embryo. Individual maternal factors, such as a high maternal age (MA) and abnormal ultrasound parameters such as embryonic bradycardia and excessively large or small yolk sac diameter (YSD) have been shown to be associated with pregnancy failures. However, few studies focused on the risk factors of the IVF population, and little is known ab out the clinical meaning of ultrasound indicators of 27–29 days after transplantation.Study design, size, durationThis was a retrospective study in a single reproductive centre. The infertile patients included in this study underwent IVF treatment between June 2016 to December 2017. Participants/materials, setting, methods: During this period, 13,977 women were identified with a singleton pregnancy by TVS at day 27 –29 after IVF-ET. The gestational sac diameter (GSD), embryonic length (EL), embryonic heart rate (EHR) and YSD and the presence of intrauterine hematoma (IUH) were measured. The clinical characteristics were also collected. Th...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research