Transcriptional and post-transcriptional regulation of CCN genes in failing heart.

CONCLUSION: CCN genes are activated in heart failure. Their regulation is multidimensional both transcriptional and posttranscriptional. The involved pathways include angiotensin II and IL-6. PMID: 25712640 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25712640?dopt=Abstract

Source: Pharmacological Reports - February 26, 2015 Category: Drugs & Pharmacology Authors: Bonda TA, Kożuch M, Litvinovich S, Bialuk I, Taranta A, Lipiec P, Szymczyk E, Musiał WJ, Winnicka MM, Kamiński KA Tags: Pharmacol Rep Source Type: research