Celiac disease presenting as a jejunal adenocarcinoma with severe iron deficiency anemia

A 60-year-old male presented to the emergency department with severe anemia (hemoglobin 6.3  g/dL) on routine follow-up. The patient reported no visible gastrointestinal blood loss. His past medical condition was unremarkable and was not taking any medication. Laboratory studies revealed a microcytic (VGM 61.6 fL) and hypochromic (CHGM 26.4 g/dL) anemia, with iron deficiency. The patient subsequently underwent upper endoscopy and colonoscopy, the latter one unremarkable. A diffuse nodular mucosa with scalloping was found in the second part of the duodenum on esophagogastroduodenoscopy, and biopsies revealed increased intraepithelial lymphocytes, villous atrophy and signs of cryptit is.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Image of the Month Source Type: research