Oncolytic virotherapy reverses chemoresistance in osteosarcoma by suppressing MDR1 expression

ConclusionOur results suggest that MDR1 is an attractive therapeutic target for chemoresistant OS. Tumor-specific virotherapy is thus a promising strategy for reversing chemoresistance in OS patients via suppression of MDR1 expression.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research