Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis

CONCLUSION: A weighted GRS for SLE was associated with an increased risk of several autoimmune-related phenotypes including type I diabetes but not with cardiometabolic disorders.PMID:33977795 | DOI:10.1177/09612033211014952

Source: Lupus - May 12, 2021 Category: Rheumatology Authors: Vivian K Kawai Mingjian Shi Ge Liu QiPing Feng WeiQi Wei Cecilia P Chung Theresa L Walunas Adam S Gordon James G Linneman Scott J Hebbring John B Harley Nancy J Cox Dan M Roden C Michael Stein Jonathan D Mosley Source Type: research