Parametric Optimization of 3D Printed Hydrogel-Based Cardiovascular Stent

ConclusionThe printed stents had sufficient mechanical strength and were stable against pseudo-physiological wall shear stress. An addition of nanofibers to alginate hydrogel significantly enhanced the biodegradation rates of the stents.In vitro cell culture studies revealed that stents had no cytotoxic effects on human umbilical vein endothelial cells (HUVECs) and Raw 264.7 cells (i.e., Monocyte/macrophage-like cells), supporting that stents are biocompatible and can be explored for future clinical applications.
Source: Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research